Protein phase separation: a new phase in cell biology S Boeynaems, S Alberti, NL Fawzi, T Mittag, M Polymenidou, F Rousseau, ... Trends in cell biology 28 (6), 420-435, 2018 | 1693 | 2018 |
Residue-by-residue view of in vitro FUS granules that bind the C-terminal domain of RNA polymerase II KA Burke, AM Janke, CL Rhine, NL Fawzi Molecular cell 60 (2), 231-241, 2015 | 829 | 2015 |
ALS mutations disrupt phase separation mediated by α-helical structure in the TDP-43 low-complexity C-terminal domain AE Conicella, GH Zerze, J Mittal, NL Fawzi Structure 24 (9), 1537-1549, 2016 | 739 | 2016 |
Phosphorylation of the FUS low‐complexity domain disrupts phase separation, aggregation, and toxicity Z Monahan, VH Ryan, AM Janke, KA Burke, SN Rhoads, GH Zerze, ... The EMBO journal 36 (20), 2951-2967, 2017 | 603 | 2017 |
Phase separation of C9orf72 dipeptide repeats perturbs stress granule dynamics S Boeynaems, E Bogaert, D Kovacs, A Konijnenberg, E Timmerman, ... Molecular cell 65 (6), 1044-1055. e5, 2017 | 507 | 2017 |
Molecular interactions underlying liquid− liquid phase separation of the FUS low-complexity domain AC Murthy, GL Dignon, Y Kan, GH Zerze, SH Parekh, J Mittal, NL Fawzi Nature structural & molecular biology 26 (7), 637-648, 2019 | 501 | 2019 |
Atomic-resolution dynamics on the surface of amyloid-β protofibrils probed by solution NMR NL Fawzi, J Ying, R Ghirlando, DA Torchia, GM Clore Nature 480 (7376), 268-272, 2011 | 435 | 2011 |
A single N‐terminal phosphomimic disrupts TDP‐43 polymerization, phase separation, and RNA splicing A Wang, AE Conicella, HB Schmidt, EW Martin, SN Rhoads, AN Reeb, ... The EMBO journal 37 (5), e97452, 2018 | 344 | 2018 |
Mechanistic view of hnRNPA2 low-complexity domain structure, interactions, and phase separation altered by mutation and arginine methylation VH Ryan, GL Dignon, GH Zerze, CV Chabata, R Silva, AE Conicella, ... Molecular cell 69 (3), 465-479. e7, 2018 | 344 | 2018 |
Nuclear import receptor inhibits phase separation of FUS through binding to multiple sites T Yoshizawa, R Ali, J Jiou, HYJ Fung, KA Burke, SJ Kim, Y Lin, ... Cell 173 (3), 693-705. e22, 2018 | 293 | 2018 |
TDP-43 α-helical structure tunes liquid–liquid phase separation and function AE Conicella, GL Dignon, GH Zerze, HB Schmidt, AM D’Ordine, YC Kim, ... Proceedings of the National Academy of Sciences 117 (11), 5883-5894, 2020 | 281 | 2020 |
SARS‐CoV‐2 nucleocapsid protein phase‐separates with RNA and with human hnRNPs TM Perdikari, AC Murthy, VH Ryan, S Watters, MT Naik, NL Fawzi The EMBO journal 39 (24), e106478, 2020 | 256* | 2020 |
Kinetics of amyloid β monomer-to-oligomer exchange by NMR relaxation NL Fawzi, J Ying, DA Torchia, GM Clore Journal of the American Chemical Society 132 (29), 9948-9951, 2010 | 207 | 2010 |
Structure and Dynamics of the Aβ21–30 Peptide from the Interplay of NMR Experiments and Molecular Simulations N L. Fawzi, AH Phillips, JZ Ruscio, M Doucleff, DE Wemmer, ... Journal of the American Chemical Society 130 (19), 6145-6158, 2008 | 183 | 2008 |
Homogeneous and heterogeneous tertiary structure ensembles of amyloid-β peptides KA Ball, AH Phillips, PS Nerenberg, NL Fawzi, DE Wemmer, ... Biochemistry 50 (35), 7612-7628, 2011 | 163 | 2011 |
Membrane bending by protein phase separation F Yuan, H Alimohamadi, B Bakka, AN Trementozzi, KJ Day, NL Fawzi, ... Proceedings of the National Academy of Sciences 118 (11), e2017435118, 2021 | 161 | 2021 |
Mice with endogenous TDP‐43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis P Fratta, P Sivakumar, J Humphrey, K Lo, T Ricketts, H Oliveira, ... The EMBO journal 37 (11), e98684, 2018 | 159 | 2018 |
Coarse-grained sequences for protein folding and design S Brown, NJ Fawzi, T Head-Gordon Proceedings of the National Academy of Sciences 100 (19), 10712-10717, 2003 | 146 | 2003 |
TDP-43 condensation properties specify its RNA-binding and regulatory repertoire M Hallegger, AM Chakrabarti, FCY Lee, BL Lee, AG Amalietti, HM Odeh, ... Cell 184 (18), 4680-4696. e22, 2021 | 143 | 2021 |
Molecular details of protein condensates probed by microsecond long atomistic simulations W Zheng, GL Dignon, N Jovic, X Xu, RM Regy, NL Fawzi, YC Kim, ... The Journal of Physical Chemistry B 124 (51), 11671-11679, 2020 | 125 | 2020 |