A dominant-negative GFI1B mutation in the gray platelet syndrome D Monteferrario, NA Bolar, AE Marneth, KM Hebeda, SM Bergevoet, ... New England Journal of Medicine 370 (3), 245-253, 2014 | 177 | 2014 |
Functional inhibition of mesenchymal stromal cells in acute myeloid leukemia S Geyh, M Rodriguez-Paredes, P Jäger, C Khandanpour, RP Cadeddu, ... Leukemia 30 (3), 683-691, 2016 | 162 | 2016 |
Origin of the brush cell lineage in the mouse intestinal epithelium M Bjerknes, C Khandanpour, T Möröy, T Fujiyama, M Hoshino, TJ Klisch, ... Developmental biology 362 (2), 194-218, 2012 | 133 | 2012 |
Acute myeloid leukemia cells polarize macrophages towards a leukemia supporting state in a Growth factor independence 1 dependent manner YS Al-Matary, L Botezatu, B Opalka, JM Hönes, RF Lams, A Thivakaran, ... Haematologica 101 (10), 1216, 2016 | 129 | 2016 |
The multiple myeloma microenvironment is defined by an inflammatory stromal cell landscape MME de Jong, Z Kellermayer, N Papazian, S Tahri, D Hofste Op Bruinink, ... Nature immunology 22 (6), 769-780, 2021 | 117 | 2021 |
From cytopenia to leukemia: the role of Gfi1 and Gfi1b in blood formation T Möröy, L Vassen, B Wilkes, C Khandanpour Blood, The Journal of the American Society of Hematology 126 (24), 2561-2569, 2015 | 111 | 2015 |
Evidence that growth factor independence 1b regulates dormancy and peripheral blood mobilization of hematopoietic stem cells C Khandanpour, E Sharif-Askari, L Vassen, MC Gaudreau, J Zhu, ... Blood, The Journal of the American Society of Hematology 116 (24), 5149-5161, 2010 | 87 | 2010 |
Growth factor independence 1 antagonizes a p53-induced DNA damage response pathway in lymphoblastic leukemia C Khandanpour, JD Phelan, L Vassen, J Schütte, R Chen, SR Horman, ... Cancer cell 23 (2), 200-214, 2013 | 82 | 2013 |
Growth factor independence 1 (Gfi1) as a regulator of lymphocyte development and activation T Möröy, C Khandanpour Seminars in immunology 23 (5), 368-378, 2011 | 72 | 2011 |
LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU. 1 target genes and induces differentiation in AML J Barth, K Abou-El-Ardat, D Dalic, N Kurrle, AM Maier, S Mohr, J Schütte, ... Leukemia 33 (6), 1411-1426, 2019 | 64 | 2019 |
Growth factor independent 1b (Gfi1b) and a new splice variant of Gfi1b are highly expressed in patients with acute and chronic leukemia L Vassen, C Khandanpour, P Ebeling, BA van der Reijden, JH Jansen, ... International journal of hematology 89, 422-430, 2009 | 61 | 2009 |
Addition of isatuximab to lenalidomide, bortezomib, and dexamethasone as induction therapy for newly diagnosed, transplantation-eligible patients with multiple myeloma (GMMG … H Goldschmidt, EK Mai, U Bertsch, R Fenk, E Nievergall, D Tichy, ... The Lancet Haematology 9 (11), e810-e821, 2022 | 59 | 2022 |
A variant allele of Growth Factor Independence 1 (GFI1) is associated with acute myeloid leukemia C Khandanpour, C Thiede, PJM Valk, E Sharif-Askari, H Nückel, ... Blood, The Journal of the American Society of Hematology 115 (12), 2462-2472, 2010 | 58 | 2010 |
GFI1 facilitates efficient DNA repair by regulating PRMT1 dependent methylation of MRE11 and 53BP1 C Vadnais, R Chen, J Fraszczak, Z Yu, J Boulais, J Pinder, D Frank, ... Nature communications 9 (1), 1418, 2018 | 57 | 2018 |
Growth factor independence 1 protects hematopoietic stem cells against apoptosis but also prevents the development of a myeloproliferative-like disease C Khandanpour, C Kosan, MC Gaudreau, U Dührsen, J Hébert, H Zeng, ... Stem cells 29 (2), 376-385, 2011 | 46 | 2011 |
The human GFI136N variant induces epigenetic changes at the Hoxa9 locus and accelerates K-RAS driven myeloproliferative disorder in mice C Khandanpour, J Krongold, J Schütte, F Bouwman, L Vassen, ... Blood, The Journal of the American Society of Hematology 120 (19), 4006-4017, 2012 | 45 | 2012 |
Zinc finger protein Gfi1 controls the endotoxin-mediated Toll-like receptor inflammatory response by antagonizing NF-κB p65 E Sharif-Askari, L Vassen, C Kosan, C Khandanpour, MC Gaudreau, ... Molecular and cellular biology 30 (16), 3929-3942, 2010 | 40 | 2010 |
Addition of isatuximab to lenalidomide, bortezomib and dexamethasone as induction therapy for newly-diagnosed, transplant-eligible multiple myeloma patients: the phase III GMMG … H Goldschmidt, EK Mai, E Nievergall, R Fenk, U Bertsch, D Tichy, ... Blood 138, 463, 2021 | 32 | 2021 |
Myelodysplastic syndromes and bone loss in mice and men H Weidner, M Rauner, F Trautmann, J Schmitt, E Balaian, A Mies, S Helas, ... Leukemia 31 (4), 1003-1007, 2017 | 31 | 2017 |
A 6-Base Pair in Frame Germline Deletion in Exon 7 Of RET Leads to Increased RET Phosphorylation, ERK Activation, and MEN2A S Latteyer, L Klein-Hitpass, C Khandanpour, D Zwanziger, TD Poeppel, ... The Journal of Clinical Endocrinology & Metabolism 101 (3), 1016-1022, 2016 | 29 | 2016 |