| Mechanism of action for leflunomide in rheumatoid arthritis RI Fox, ML Herrmann, CG Frangou, GM Wahl, RE Morris, V Strand, ... Clinical Immunology 93 (3), 198-208, 1999 | 424 | 1999 |
| PRAK is essential for ras-induced senescence and tumor suppression P Sun, N Yoshizuka, L New, BA Moser, Y Li, R Liao, C Xie, J Chen, ... Cell 128 (2), 295-308, 2007 | 388 | 2007 |
| Leflunomide: an immunomodulatory drug for the treatment of rheumatoid arthritis and other autoimmune diseases ML Herrmann, R Schleyerbach, BJ Kirschbaum Immunopharmacology 47 (2-3), 273-289, 2000 | 328 | 2000 |
| p53 cooperates with DNA methylation and a suicidal interferon response to maintain epigenetic silencing of repeats and noncoding RNAs KI Leonova, L Brodsky, B Lipchick, M Pal, L Novototskaya, AA Chenchik, ... Proceedings of the National Academy of Sciences 110 (1), E89-E98, 2013 | 272 | 2013 |
| Bivalent domains enforce transcriptional memory of DNA methylated genes in cancer cells J Rodriguez, M Muñoz, L Vives, CG Frangou, M Groudine, MA Peinado Proceedings of the National Academy of Sciences 105 (50), 19809-19814, 2008 | 126 | 2008 |
| VGLL4 selectively represses YAP-dependent gene induction and tumorigenic phenotypes in breast cancer Y Zhang, H Shen, HG Withers, N Yang, KE Denson, AL Mussell, ... Scientific reports 7 (1), 6190, 2017 | 68 | 2017 |
| Characterization of TAZ domains important for the induction of breast cancer stem cell properties and tumorigenesis YW Li, H Shen, C Frangou, N Yang, J Guo, B Xu, W Bshara, L Shepherd, ... Cell cycle 14 (1), 146-156, 2015 | 56 | 2015 |
| How does leflunomide modulate the immune response in rheumatoid arthritis? RI Fox, ML Herrmann, CG Frangou, GM Wahl, RE Morris, BJ Kirschbaum BioDrugs 12 (4), 301-315, 1999 | 53 | 1999 |
| TRAIN (Transcription of Repeats Activates INterferon) in response to chromatin destabilization induced by small molecules in mammalian cells K Leonova, A Safina, E Nesher, P Sandlesh, R Pratt, C Burkhart, ... Elife 7, e30842, 2018 | 50 | 2018 |
| Sox4 expression confers bladder cancer stem cell properties and predicts for poor patient outcome H Shen, M Blijlevens, N Yang, C Frangou, KE Wilson, B Xu, Y Zhang, ... International journal of biological sciences 11 (12), 1363, 2015 | 46 | 2015 |
| The ULT1 and ULT2 trxG genes play overlapping roles in Arabidopsis development and gene regulation MM Monfared, CC Carles, P Rossignol, HR Pires, JC Fletcher Molecular Plant 6 (5), 1564-1579, 2013 | 45 | 2013 |
| USP1 regulates TAZ protein stability through ubiquitin modifications in breast cancer A Mussell, H Shen, Y Chen, M Mastri, KH Eng, W Bshara, C Frangou, ... Cancers 12 (11), 3090, 2020 | 40 | 2020 |
| Identification of MALT1 feedback mechanisms enables rational design of potent antilymphoma regimens for ABC-DLBCL L Fontan, R Goldstein, G Casalena, M Durant, MR Teater, J Wilson, ... Blood, The Journal of the American Society of Hematology 137 (6), 788-800, 2021 | 33 | 2021 |
| Molecular profiling and computational network analysis of TAZ-mediated mammary tumorigenesis identifies actionable therapeutic targets C Frangou, YW Li, H Shen, N Yang, KE Wilson, M Blijlevens, J Guo, ... Oncotarget 5 (23), 12166, 2014 | 32 | 2014 |
| 6p22. 3 amplification as a biomarker and potential therapeutic target of advanced stage bladder cancer H Shen, CD Morrison, J Zhang, W Underwood III, N Yang, C Frangou, ... Oncotarget 4 (11), 2124, 2013 | 31 | 2013 |
| Tumor-derived CTF1 (cardiotrophin 1) is a critical mediator of stroma-assisted and autophagy-dependent breast cancer cell migration, invasion and metastasis Y Akkoc, K Dalci, HE Karakas, S Erbil-Bilir, O Yalav, G Sakman, F Celik, ... Autophagy 19 (1), 306-323, 2023 | 24 | 2023 |
| NTRK1 is a positive regulator of YAP oncogenic function X Yang, H Shen, B Buckley, Y Chen, N Yang, AL Mussell, M Chernov, ... Oncogene 38 (15), 2778-2787, 2019 | 24 | 2019 |
| Phosphorylation of Tyr188 in the WW domain of YAP1 plays an essential role in YAP1-induced cellular transformation YW Li, J Guo, H Shen, J Li, N Yang, C Frangou, KE Wilson, Y Zhang, ... Cell cycle 15 (18), 2497-2505, 2016 | 18 | 2016 |
| Vascular priming enhances chemotherapeutic efficacy against head and neck cancer M Folaron, J Kalmuk, J Lockwood, C Frangou, J Vokes, SG Turowski, ... Oral oncology 49 (9), 893-902, 2013 | 16 | 2013 |
| Targeting TAZ-driven human breast cancer by inhibiting a SKP2-p27 signaling axis H Shen, N Yang, A Truskinovsky, Y Chen, AL Mussell, NJ Nowak, ... Molecular Cancer Research 17 (1), 250-262, 2019 | 15 | 2019 |
