Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism SB Prusiner, AL Woerman, DA Mordes, JC Watts, R Rampersaud, ... Proceedings of the National Academy of Sciences 112 (38), E5308-E5317, 2015 | 746 | 2015 |
Propagation of prions causing synucleinopathies in cultured cells AL Woerman, J Stöhr, A Aoyagi, R Rampersaud, Z Krejciova, JC Watts, ... Proceedings of the National Academy of Sciences 112 (35), E4949-E4958, 2015 | 248 | 2015 |
Tau prions from Alzheimer’s disease and chronic traumatic encephalopathy patients propagate in cultured cells AL Woerman, A Aoyagi, S Patel, SA Kazmi, I Lobach, LT Grinberg, ... Proceedings of the National Academy of Sciences 113 (50), E8187-E8196, 2016 | 171 | 2016 |
Tau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components E Lester, FK Ooi, N Bakkar, J Ayers, AL Woerman, J Wheeler, R Bowser, ... Neuron 109 (10), 1675-1691. e9, 2021 | 129 | 2021 |
Aβ and tau prion-like activities decline with longevity in the Alzheimer’s disease human brain A Aoyagi, C Condello, J Stöhr, W Yue, BM Rivera, JC Lee, AL Woerman, ... Science translational medicine 11 (490), eaat8462, 2019 | 126 | 2019 |
MSA prions exhibit remarkable stability and resistance to inactivation AL Woerman, SA Kazmi, S Patel, Y Freyman, A Oehler, A Aoyagi, ... Acta neuropathologica 135 (1), 49-63, 2018 | 84 | 2018 |
α-Synuclein: multiple system atrophy prions AL Woerman, JC Watts, A Aoyagi, K Giles, LT Middleton, SB Prusiner Cold Spring Harbor perspectives in medicine 8 (7), a024588, 2018 | 82 | 2018 |
Multiple system atrophy prions retain strain specificity after serial propagation in two different Tg(SNCA*A53T) mouse lines AL Woerman, A Oehler, SA Kazmi, J Lee, GM Halliday, LT Middleton, ... Acta neuropathologica 137, 437-454, 2019 | 75 | 2019 |
Evidence of distinct α-synuclein strains underlying disease heterogeneity SAM Holec, AL Woerman Acta neuropathologica 142, 73-86, 2021 | 67 | 2021 |
Different α-synuclein prion strains cause dementia with Lewy bodies and multiple system atrophy JI Ayers, J Lee, O Monteiro, AL Woerman, AA Lazar, C Condello, ... Proceedings of the National Academy of Sciences 119 (6), e2113489119, 2022 | 48 | 2022 |
Familial Parkinson’s point mutation abolishes multiple system atrophy prion replication AL Woerman, SA Kazmi, S Patel, A Aoyagi, A Oehler, K Widjaja, ... Proceedings of the National Academy of Sciences 115 (2), 409-414, 2018 | 41 | 2018 |
Bioassays and inactivation of prions K Giles, AL Woerman, DB Berry, SB Prusiner Cold Spring Harbor perspectives in biology 9 (8), a023499, 2017 | 39 | 2017 |
Kinetics of human mutant tau prion formation in the brains of 2 transgenic mouse lines AL Woerman, S Patel, SA Kazmi, A Oehler, Y Freyman, L Espiritu, ... JAMA neurology 74 (12), 1464-1472, 2017 | 33 | 2017 |
Mouse closed head traumatic brain injury replicates the histological tau pathology pattern of human disease: characterization of a novel model and systematic review of the … A Kahriman, J Bouley, TW Smith, DA Bosco, AL Woerman, N Henninger Acta Neuropathologica Communications 9 (1), 118, 2021 | 32 | 2021 |
Tau interactome analyses in CRISPR-Cas9 engineered neuronal cells reveal ATPase-dependent binding of wild-type but not P301L tau to non-muscle myosins X Wang, D Williams, I Müller, M Lemieux, R Dukart, IBL Maia, H Wang, ... Scientific reports 9 (1), 1-21, 2019 | 28 | 2019 |
Kinetics of α-synuclein prions preceding neuropathological inclusions in multiple system atrophy AL Woerman, S Patel, SA Kazmi, A Oehler, J Lee, DA Mordes, SH Olson, ... PLoS Pathogens 16 (2), e1008222, 2020 | 26 | 2020 |
Consequences of variability in α-synuclein fibril structure on strain biology SAM Holec, SL Liu, AL Woerman Acta Neuropathologica 143 (3), 311-330, 2022 | 21 | 2022 |
Modulation of bulbospinal rostral ventral lateral medulla neurons by hypoxia/hypercapnia but not medullary respiratory activity CR Boychuk, AL Woerman, D Mendelowitz Hypertension 60 (6), 1491-1497, 2012 | 21 | 2012 |
Multiple system atrophy prions transmit neurological disease to mice expressing wild-type human α-synuclein SAM Holec, J Lee, A Oehler, FK Ooi, DA Mordes, SH Olson, SB Prusiner, ... Acta neuropathologica 144 (4), 677-690, 2022 | 12 | 2022 |
Prenatal nicotine exposure enhances the trigeminocardiac reflex via serotonin receptor facilitation in brainstem pathways C Gorini, H Jameson, AL Woerman, DC Perry, D Mendelowitz Journal of Applied Physiology 115 (4), 415-421, 2013 | 12 | 2013 |