| Advances in targeting cyclic nucleotide phosphodiesterases DH Maurice, H Ke, F Ahmad, Y Wang, J Chung, VC Manganiello Nature reviews Drug discovery 13 (4), 290-314, 2014 | 820 | 2014 |
| Molecular basis of the synergistic inhibition of platelet function by nitrovasodilators and activators of adenylate cyclase: inhibition of cyclic AMP breakdown by cyclic GMP. DH Maurice, RJ Haslam Molecular pharmacology 37 (5), 671-681, 1990 | 427 | 1990 |
| Cyclic nucleotide phosphodiesterase activity, expression, and targeting in cells of the cardiovascular system DH Maurice, D Palmer, DG Tilley, HA Dunkerley, SJ Netherton, ... Molecular pharmacology 64 (3), 533-546, 2003 | 410 | 2003 |
| cAMP-Specific phosphodiesterase-4 enzymes in the cardiovascular system: a molecular toolbox for generating compartmentalized cAMP signaling MD Houslay, GS Baillie, DH Maurice Circulation research 100 (7), 950-966, 2007 | 367 | 2007 |
| Selective inhibition of heme oxygenase, without inhibition of nitric oxide synthase or soluble guanylyl cyclase, by metalloporphyrins at low concentrations SD Appleton, ML Chretien, BE McLaughlin, HJ Vreman, DK Stevenson, ... Drug metabolism and disposition 27 (10), 1214-1219, 1999 | 231 | 1999 |
| Cleavage of the matricellular protein SPARC by matrix metalloproteinase 3 produces polypeptides that influence angiogenesis EH Sage, M Reed, SE Funk, T Truong, M Steadele, P Puolakkainen, ... Journal of Biological Chemistry 278 (39), 37849-37857, 2003 | 204 | 2003 |
| Cyclic nucleotide phosphodiesterases: important signaling modulators and therapeutic targets F Ahmad, T Murata, K Shimizu, E Degerman, D Maurice, V Manganiello Oral diseases 21 (1), e25-e50, 2015 | 169 | 2015 |
| Vascular endothelial cell cyclic nucleotide phosphodiesterases and regulated cell migration: implications in angiogenesis SJ Netherton, DH Maurice Molecular pharmacology 67 (1), 263-272, 2005 | 153 | 2005 |
| Expression of cyclic GMP‐inhibited phosphodiesterases 3A and 3B (PDE3A and PDE3B) in rat tissues: differential subcellular localization and regulated expression by cyclic AMP H Liu, DH Maurice British journal of pharmacology 125 (7), 1501-1510, 1998 | 137 | 1998 |
| PI3Kγ is required for PDE4, not PDE3, activity in subcellular microdomains containing the sarcoplasmic reticular calcium ATPase in cardiomyocytes BG Kerfant, D Zhao, I Lorenzen-Schmidt, LS Wilson, S Cai, SRW Chen, ... Circulation research 101 (4), 400-408, 2007 | 126 | 2007 |
| Synergistic inhibition of vascular smooth muscle cell migration by phosphodiesterase 3 and phosphodiesterase 4 inhibitors D Palmer, K Tsoi, DH Maurice Circulation research 82 (8), 852-861, 1998 | 116 | 1998 |
| Phosphorylation-mediated activation and translocation of the cyclic AMP-specific phosphodiesterase PDE4D3 by cyclic AMP-dependent protein kinase and mitogen-activated protein … H Liu, DH Maurice Journal of Biological Chemistry 274 (15), 10557-10565, 1999 | 113 | 1999 |
| Cyclic AMP phosphodiesterase 4D (PDE4D) Tethers EPAC1 in a vascular endothelial cadherin (VE-Cad)-based signaling complex and controls cAMP-mediated vascular permeability SN Rampersad, JD Ovens, E Huston, MB Umana, LS Wilson, ... Journal of Biological Chemistry 285 (44), 33614-33622, 2010 | 109 | 2010 |
| Expression of phosphodiesterase 4D (PDE4D) is regulated by both the cyclic AMP-dependent protein kinase and mitogen-activated protein kinase signaling pathways: a potential … H Liu, D Palmer, SL Jimmo, DG Tilley, HA Dunkerley, SC Pang, ... Journal of Biological Chemistry 275 (34), 26615-26624, 2000 | 108 | 2000 |
| Phosphodiesterase 4D Regulates Baseline Sarcoplasmic Reticulum Ca2+ Release and Cardiac Contractility, Independently of L-Type Ca2+ Current S Beca, PB Helli, JA Simpson, D Zhao, GP Farman, PP Jones, X Tian, ... Circulation research 109 (9), 1024-1030, 2011 | 104 | 2011 |
| Leptin-mediated activation of human platelets: involvement of a leptin receptor and phosphodiesterase 3A-containing cellular signaling complex HS Elbatarny, DH Maurice American Journal of Physiology-Endocrinology and Metabolism 289 (4), E695-E702, 2005 | 95 | 2005 |
| Compartmentation and compartment-specific regulation of PDE5 by protein kinase G allows selective cGMP-mediated regulation of platelet functions LS Wilson, HS Elbatarny, SW Crawley, BM Bennett, DH Maurice Proceedings of the National Academy of Sciences 105 (36), 13650-13655, 2008 | 93 | 2008 |
| Synergistic actions of nitrovasodilators and isoprenaline on rat aortic smooth muscle DH Maurice, D Crankshaw, RJ Haslam European journal of pharmacology 192 (2), 235-242, 1991 | 93 | 1991 |
| Nitroprusside enhances isoprenaline-induced increases in cAMP in rat aortic smooth muscle DH Maurice, RJ Haslam European journal of pharmacology 191 (3), 471-475, 1990 | 90 | 1990 |
| Adiponectin, ghrelin, and leptin differentially influence human platelet and human vascular endothelial cell functions: implication in obesity-associated cardiovascular diseases HS Elbatarny, SJ Netherton, JD Ovens, AV Ferguson, DH Maurice European Journal of Pharmacology 558 (1-3), 7-13, 2007 | 84 | 2007 |
Douglas TilleyAging + Cardiovascular Discovery Center, Lewis Katz School of Medicine at Temple University在 temple.edu 的电子邮件经过验证
