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Graeme Sullivan
Graeme Sullivan
在 tcd.ie 的电子邮件经过验证
标题
引用次数
引用次数
年份
Neutrophil-derived proteases escalate inflammation through activation of IL-36 family cytokines
CM Henry, GP Sullivan, DM Clancy, IS Afonina, D Kulms, SJ Martin
Cell reports 14 (4), 708-722, 2016
3322016
Extracellular neutrophil proteases are efficient regulators of IL-1, IL-33, and IL-36 cytokine activity but poor effectors of microbial killing
DM Clancy, GP Sullivan, HBT Moran, CM Henry, EP Reeves, ...
Cell reports 22 (11), 2937-2950, 2018
1962018
Neutrophil extracellular traps can serve as platforms for processing and activation of IL‐1 family cytokines
DM Clancy, CM Henry, GP Sullivan, SJ Martin
The FEBS journal 284 (11), 1712-1725, 2017
1212017
iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE
I Oikonomidi, E Burbridge, M Cavadas, G Sullivan, B Collis, H Naegele, ...
Elife 7, e35032, 2018
642018
TRAIL receptors serve as stress-associated molecular patterns to promote ER-stress-induced inflammation
GP Sullivan, H O’Connor, CM Henry, P Davidovich, DM Clancy, ML Albert, ...
Developmental Cell 52 (6), 714-730. e5, 2020
532020
Suppressing IL-36-driven inflammation using peptide pseudosubstrates for neutrophil proteases
GP Sullivan, CM Henry, DM Clancy, T Mametnabiev, E Belotcerkovskaya, ...
Cell death & disease 9 (3), 378, 2018
482018
Identification of small‐molecule elastase inhibitors as antagonists of IL‐36 cytokine activation
GP Sullivan, PB Davidovich, S Sura‐Trueba, E Belotcerkovskaya, ...
FEBS open bio 8 (5), 751-763, 2018
212018
Production of biologically active IL‐36 family cytokines through insertion of N‐terminal caspase cleavage motifs
DM Clancy, CM Henry, PB Davidovich, GP Sullivan, E Belotcerkovskaya, ...
FEBS Open Bio 6 (4), 338-348, 2016
192016
The path to venetoclax resistance is paved with mutations, metabolism, and more
GP Sullivan, L Flanagan, DA Rodrigues, T Ní Chonghaile
Science Translational Medicine 14 (674), eabo6891, 2022
142022
Myeloid cell–derived proteases produce a proinflammatory form of IL-37 that signals via IL-36 receptor engagement
GP Sullivan, P Davidovich, N Muñoz-Wolf, RW Ward, ...
Science Immunology 7 (78), eade5728, 2022
62022
Extracellular neutrophil proteases are efficient regulators of IL-1, IL-33, and IL-36 cytokine activity but poor effectors of microbial killing. Cell Rep 2018; 22: 2937-50
DM Clancy, GP Sullivan, HBT Moran, CM Henry, EP Reeves, ...
52018
IL-1α and IL-36 family cytokines can undergo processing and activation by diverse allergen-associated proteases
V Frezza, Z Najda, P Davidovich, GP Sullivan, SJ Martin
Frontiers in Immunology 13, 879029, 2022
42022
Use of inhibitors of il-36 proteolytic processing for the treatment and/or reduction of inflammation
SJ Martin, C Henry, G Sullivan
US Patent App. 15/512,139, 2017
22017
First-in-class metallo-PROTAC as an effective degrader of select Pt-binding proteins
PD O’Dowd, GP Sullivan, DA Rodrigues, TN Chonghaile, DM Griffith
Chemical Communications 59 (84), 12641-12644, 2023
12023
Method for treatment of inflammatory skin disorders with inhibitors of IL-36 proteolytic processing
SJ Martin, C Henry, G Sullivan
US Patent 10,744,179, 2020
2020
Inflammatory Outcomes of Diverse Forms of Homeostatic Perturbation
G Sullivan
Trinity College Dublin, 2018
2018
Use of inhibitors of il-36 proteolytic processing for the treatment and/or reduction of inflammation
SJ Martin, C Henry, G Sullivan
2016
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