The codon 72 polymorphic variants of p53 have markedly different apoptotic potential P Dumont, JL Leu, AC Della Pietra, DL George, M Murphy Nature genetics 33 (3), 357-365, 2003 | 1564 | 2003 |
Mitochondrial p53 activates Bak and causes disruption of a Bak–Mcl1 complex JIJ Leu, P Dumont, M Hafey, ME Murphy, DL George Nature cell biology 6 (5), 443-450, 2004 | 1015 | 2004 |
Induction of replicative senescence biomarkers by sublethal oxidative stresses in normal human fibroblast P Dumont, M Burton, QM Chen, ES Gonos, C Frippiat, JB Mazarati, ... Free Radical Biology and Medicine 28 (3), 361-373, 2000 | 465 | 2000 |
The Amaryllidaceae isocarbostyril narciclasine induces apoptosis by activation of the death receptor and/or mitochondrial pathways in cancer cells but not in normal fibroblasts P Dumont, L Ingrassia, S Rouzeau, F Ribaucour, S Thomas, I Roland, ... Neoplasia 9 (9), 766-776, 2007 | 207 | 2007 |
Cardenolide-induced lysosomal membrane permeabilization demonstrates therapeutic benefits in experimental human non-small cell lung cancers T Mijatovic, V Mathieu, JF Gaussin, N De Néve, F Ribaucour, ... Neoplasia 8 (5), 402-412, 2006 | 169 | 2006 |
2,2,2-Trichloro-N-({2-[2-(dimethylamino)ethyl]-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin- 5-yl}carbamoyl)acetamide (UNBS3157), a Novel Nonhematotoxic … E Van Quaquebeke, T Mahieu, P Dumont, J Dewelle, F Ribaucour, ... Journal of medicinal chemistry 50 (17), 4122-4134, 2007 | 158 | 2007 |
The codon 47 polymorphism in p53 is functionally significant X Li, P Dumont, A Della Pietra, C Shetler, ME Murphy Journal of Biological Chemistry 280 (25), 24245-24251, 2005 | 140 | 2005 |
Stress‐Induced Premature Senescence: Essence of Life, Evolution, Stress, and Aging O Toussaint, P Dumont, JF DIERICK, T Pascal, C Frippiat, F Chainiaux, ... Annals of the New York Academy of Sciences 908 (1), 85-98, 2000 | 134 | 2000 |
Overexpression of apolipoprotein J in human fibroblasts protects against cytotoxicity and premature senescence induced by ethanol and tert-butylhydroperoxide P Dumont, F Chainiaux, F Eliaers, C Petropoulou, J Remacle, ... Cell stress & chaperones 7 (1), 23, 2002 | 108 | 2002 |
Stress‐Induced Premature Senescence or Stress‐Induced Senescence‐Like Phenotype: One In Vivo Reality, Two Possible Definitions? O Toussaint, P Dumont, J Remacle, JF Dierick, T Pascal, C Frippiat, ... The Scientific World JOURNAL 2 (1), 230-247, 2002 | 106 | 2002 |
Resveratrol induces DNA damage in colon cancer cells by poisoning topoisomerase II and activates the ATM kinase to trigger p53-dependent apoptosis B Demoulin, M Hermant, C Castrogiovanni, C Staudt, P Dumont Toxicology in vitro 29 (5), 1156-1165, 2015 | 98 | 2015 |
Serine 392 phosphorylation modulates p53 mitochondrial translocation and transcription-independent apoptosis C Castrogiovanni, B Waterschoot, O De Backer, P Dumont Cell Death & Differentiation 25 (1), 190-203, 2018 | 87 | 2018 |
Appearance of biomarkers of in vitro ageing after successive stimulation of WI‐38 fibroblasts with IL‐1α and TNF‐α: senescence associated β‐galactosidase activity and … P Dumont, L Balbeur, J Remacle, O Toussaint Journal of anatomy 197 (4), 529-537, 2000 | 67 | 2000 |
Growth kinetics rather than stress accelerate telomere shortening in cultures of human diploid fibroblasts in oxidative stress‐induced premature senescence P Dumont, V Royer, T Pascal, JF Dierick, F Chainiaux, C Frippiat, ... FEBS letters 502 (3), 109-112, 2001 | 66 | 2001 |
Wild-type and mutant p53 proteins interact with mitochondrial caspase-3 AK Frank, EC Pietsch, P Dumont, J Tao, ME Murphy Cancer biology & therapy 11 (8), 740-745, 2011 | 64 | 2011 |
Expression of galectin-3 in the tumor immune response in colon cancer P Dumont, A Berton, N Nagy, F Sandras, S Tinton, P Demetter, F Mascart, ... Laboratory investigation 88 (8), 896-906, 2008 | 59 | 2008 |
The galectin family and digestive disease P Demetter, N Nagy, B Martin, A Mathieu, P Dumont, C Decaestecker, ... The Journal of Pathology: A Journal of the Pathological Society of Great …, 2008 | 57 | 2008 |
The tetramerization domain of p53 is required for efficient BAK oligomerization EC Pietsch, JIJ Leu, AK Frank, P Dumont, DL George, ME Murphy Cancer biology & therapy 6 (10), 1576-1583, 2007 | 40 | 2007 |
Stress-induced premature senescence as alternativetoxicological method for testing the long-term effectsof molecules under development in the industry O Toussaint, P Dumont, JF Dierick, T Pascal, C Frippiat, F Chainiaux, ... Biogerontology 1, 179-183, 2000 | 38 | 2000 |
Reciprocal Relationships between the Resistance to Stresses and Cellular Aginga O Toussaint, SY Fuchs, ZA Ronai, S Isoyama, N Yuko, V Petronilli, ... Annals of the New York Academy of Sciences 851 (1), 450-465, 1998 | 30 | 1998 |