A molecular mechanism for eflornithine resistance in African trypanosomes IM Vincent, D Creek, DG Watson, MA Kamleh, DJ Woods, PE Wong, ... PLoS pathogens 6 (11), e1001204, 2010 | 224 | 2010 |
Drug resistance in human African trypanosomiasis MP Barrett, IM Vincent, RJS Burchmore, AJN Kazibwe, E Matovu Future microbiology 6 (9), 1037-1047, 2011 | 181 | 2011 |
Untargeted Metabolomics Reveals a Lack Of Synergy between Nifurtimox and Eflornithine against Trypanosoma brucei IM Vincent, DJ Creek, K Burgess, DJ Woods, RJS Burchmore, MP Barrett PLoS neglected tropical diseases 6 (5), e1618, 2012 | 120 | 2012 |
Untargeted metabolomics to ascertain antibiotic modes of action IM Vincent, DE Ehmann, SD Mills, M Perros, MP Barrett Antimicrobial agents and chemotherapy 60 (4), 2281-2291, 2016 | 94 | 2016 |
The threonine degradation pathway of the Trypanosoma brucei procyclic form: the main carbon source for lipid biosynthesis is under metabolic control Y Millerioux, C Ebikeme, M Biran, P Morand, G Bouyssou, IM Vincent, ... Molecular microbiology 90 (1), 114-129, 2013 | 81 | 2013 |
Untargeted metabolomic analysis of miltefosine action in Leishmania infantum reveals changes to the internal lipid metabolism IM Vincent, S Weidt, L Rivas, K Burgess, TK Smith, M Ouellette International Journal for Parasitology: Drugs and Drug Resistance 4 (1), 20-27, 2014 | 80 | 2014 |
Metabolomic-based strategies for anti-parasite drug discovery IM Vincent, MP Barrett Journal of biomolecular screening 20 (1), 44-55, 2015 | 67 | 2015 |
The trypanocidal benzoxaborole AN7973 inhibits trypanosome mRNA processing D Begolo, IM Vincent, F Giordani, I Pöhner, MJ Witty, TG Rowan, ... PLoS pathogens 14 (9), e1007315, 2018 | 63 | 2018 |
Different Mutations in a P-type ATPase Transporter in Leishmania Parasites are Associated with Cross-resistance to Two Leading Drugs by Distinct Mechanisms C Fernandez-Prada, IM Vincent, MC Brotherton, M Roberts, G Roy, ... PLoS neglected tropical diseases 10 (12), e0005171, 2016 | 63 | 2016 |
Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana R Mwenechanya, J Kovářová, NJ Dickens, M Mudaliar, P Herzyk, ... PLoS neglected tropical diseases 11 (6), e0005649, 2017 | 60 | 2017 |
Metabolomic profiling of macrophages determines the discrete metabolomic signature and metabolomic interactome triggered by polarising immune stimuli KM Rattigan, AW Pountain, C Regnault, F Achcar, IM Vincent, ... PloS one 13 (3), e0194126, 2018 | 47 | 2018 |
Benzoxaborole treatment perturbs S-adenosyl-L-methionine metabolism in Trypanosoma brucei PC Steketee, IM Vincent, F Achcar, F Giordani, DH Kim, DJ Creek, ... PLoS neglected tropical diseases 12 (5), e0006450, 2018 | 44 | 2018 |
Metabolomics identifies multiple candidate biomarkers to diagnose and stage human African trypanosomiasis IM Vincent, R Daly, B Courtioux, AM Cattanach, S Biéler, JM Ndung’u, ... PLoS neglected tropical diseases 10 (12), e0005140, 2016 | 43 | 2016 |
TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei S Shameer, FJ Logan-Klumpler, F Vinson, L Cottret, B Merlet, F Achcar, ... Nucleic acids research 43 (D1), D637-D644, 2015 | 39 | 2015 |
Host-parasite co-metabolic activation of antitrypanosomal aminomethyl-benzoxaboroles N Zhang, M Zoltner, KF Leung, P Scullion, S Hutchinson, RC Del Pino, ... Plos Pathogens 14 (2), e1006850, 2018 | 33 | 2018 |
Mitochondrial Proteomics of Antimony and Miltefosine Resistant Leishmania infantum IM Vincent, G Racine, D Légaré, M Ouellette Proteomes 3 (4), 328-346, 2015 | 30 | 2015 |
Ranking metabolite sets by their activity levels K McLuskey, J Wandy, I Vincent, JJJ Van Der Hooft, S Rogers, K Burgess, ... Metabolites 11 (2), 103, 2021 | 21 | 2021 |
Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs F Giordani, D Paape, IM Vincent, AW Pountain, F Fernández-Cortés, ... PLoS pathogens 16 (11), e1008932, 2020 | 21 | 2020 |
Inhibition of glycolysis and mitochondrial respiration promotes radiosensitisation of neuroblastoma and glioma cells DL Nile, C Rae, DJ Walker, JC Waddington, I Vincent, K Burgess, ... Cancer & Metabolism 9 (1), 24, 2021 | 19 | 2021 |
Polymeric hydrophilic interaction liquid chromatography coupled with Orbitrap mass spectrometry and chemometric analysis for untargeted metabolite profiling of natural rice … MI Akram, IM Vincent, AJ Siddiqui, SG Musharraf Journal of Cereal Science 73, 165-173, 2017 | 10 | 2017 |