| Towards an understanding of amyloid-β oligomers: characterization, toxicity mechanisms, and inhibitors SJC Lee, E Nam, HJ Lee, MG Savelieff, MH Lim Chemical Society Reviews 46 (2), 310-323, 2017 | 504 | 2017 |
| Development of multifunctional molecules as potential therapeutic candidates for Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis in the last decade MG Savelieff, G Nam, J Kang, HJ Lee, M Lee, MH Lim Chemical reviews 119 (2), 1221-1322, 2018 | 449 | 2018 |
| Rational design of a structural framework with potential use to develop chemical reagents that target and modulate multiple facets of Alzheimer’s disease S Lee, X Zheng, J Krishnamoorthy, MG Savelieff, HM Park, JR Brender, ... Journal of the American Chemical Society 136 (1), 299-310, 2014 | 205 | 2014 |
| Cholesterol and metal ions in Alzheimer's disease HJ Lee, KJ Korshavn, A Kochi, JS Derrick, MH Lim Chemical Society Reviews 43 (19), 6672-6682, 2014 | 95 | 2014 |
| A rationally designed small molecule for identifying an in vivo link between metal–amyloid-β complexes and the pathogenesis of Alzheimer's disease MW Beck, SB Oh, RA Kerr, HJ Lee, SH Kim, S Kim, M Jang, BT Ruotolo, ... Chemical Science 6 (3), 1879-1886, 2015 | 75 | 2015 |
| Molecular insights into human serum albumin as a receptor of amyloid-β in the extracellular region TS Choi, HJ Lee, JY Han, MH Lim, HI Kim Journal of the American Chemical Society 139 (43), 15437-15445, 2017 | 70 | 2017 |
| A redox-active, compact molecule for cross-linking amyloidogenic peptides into nontoxic, off-pathway aggregates: in vitro and in vivo efficacy and molecular mechanisms JS Derrick, RA Kerr, Y Nam, SB Oh, HJ Lee, KG Earnest, N Suh, KL Peck, ... Journal of the American Chemical Society 137 (46), 14785-14797, 2015 | 69 | 2015 |
| A small molecule that displays marked reactivity toward copper–versus zinc–amyloid-β implicated in Alzheimer's disease MG Savelieff, Y Liu, RRP Senthamarai, KJ Korshavn, HJ Lee, ... Chemical Communications 50 (40), 5301-5303, 2014 | 60 | 2014 |
| Structure and assembly mechanisms of toxic human islet amyloid polypeptide oligomers associated with copper SJC Lee, TS Choi, JW Lee, HJ Lee, DG Mun, S Akashi, SW Lee, MH Lim, ... Chemical Science 7 (8), 5398-5406, 2016 | 45 | 2016 |
| Inhibitory activity of curcumin derivatives towards metal-free and metal-induced amyloid-β aggregation A Kochi, H Jin Lee, S M Vithanarachchi, V Padmini, M J Allen, M Hee Lim Current Alzheimer Research 12 (5), 415-423, 2015 | 42 | 2015 |
| An iridium (III) complex as a photoactivatable tool for oxidation of amyloidogenic peptides with subsequent modulation of peptide aggregation J Kang, SJC Lee, JS Nam, HJ Lee, MG Kang, KJ Korshavn, HT Kim, ... Chemistry–A European Journal 23 (7), 1645-1653, 2017 | 40 | 2017 |
| Synthetic flavonoids, aminoisoflavones: interaction and reactivity with metal-free and metal-associated amyloid-β species AS DeToma, J Krishnamoorthy, Y Nam, HJ Lee, JR Brender, A Kochi, ... Chemical science (Royal Society of Chemistry: 2010) 5 (12), 4851, 2014 | 39 | 2014 |
| Redox-active metal ions and amyloid-degrading enzymes in Alzheimer’s disease N Kim, HJ Lee International Journal of Molecular Sciences 22 (14), 7697, 2021 | 33 | 2021 |
| Effects of hydroxyl group variations on a flavonoid backbone toward modulation of metal-free and metal-induced amyloid-β aggregation HJ Lee, RA Kerr, KJ Korshavn, J Lee, J Kang, A Ramamoorthy, ... Inorganic Chemistry Frontiers 3 (3), 381-392, 2016 | 32 | 2016 |
| Structural and Mechanistic Insights into Development of Chemical Tools to Control Individual and Inter‐Related Pathological Features in Alzheimer's Disease HJ Lee, KJ Korshavn, Y Nam, J Kang, TJ Paul, RA Kerr, IS Youn, M Ozbil, ... Chemistry–A European Journal 23 (11), 2706-2715, 2017 | 31 | 2017 |
| Multiple reactivities of flavonoids towards pathological elements in Alzheimer's disease: structure–activity relationship G Nam, M Hong, J Lee, HJ Lee, Y Ji, J Kang, MH Baik, MH Lim Chemical Science 11 (37), 10243-10254, 2020 | 29 | 2020 |
| Tuning structures and properties for developing novel chemical tools toward distinct pathogenic elements in Alzheimer’s disease J Han, HJ Lee, KY Kim, SJC Lee, JM Suh, J Cho, J Chae, MH Lim ACS Chemical Neuroscience 9 (4), 800-808, 2017 | 29 | 2017 |
| Minimalistic principles for designing small molecules with multiple reactivities against pathological factors in dementia M Kim, J Kang, M Lee, J Han, G Nam, E Tak, MS Kim, HJ Lee, E Nam, ... Journal of the American Chemical Society 142 (18), 8183-8193, 2020 | 28 | 2020 |
| Mechanistic approaches for chemically modifying the coordination sphere of copper–amyloid-β complexes J Han, HJ Lee, KY Kim, G Nam, J Chae, MH Lim Proceedings of the National Academy of Sciences 117 (10), 5160-5167, 2020 | 28 | 2020 |
| Chemical strategies to modify amyloidogenic peptides using iridium (iii) complexes: Coordination and photo-induced oxidation J Kang, JS Nam, HJ Lee, G Nam, HW Rhee, TH Kwon, MH Lim Chemical science 10 (28), 6855-6862, 2019 | 26 | 2019 |
