| Crystal structures of cyclohexanone monooxygenase reveal complex domain movements and a sliding cofactor IA Mirza, BJ Yachnin, S Wang, S Grosse, H Bergeron, A Imura, H Iwaki, ... Journal of the American Chemical Society 131 (25), 8848-8854, 2009 | 210 | 2009 |
| The substrate-bound crystal structure of a Baeyer–Villiger monooxygenase exhibits a Criegee-like conformation BJ Yachnin, T Sprules, MB McEvoy, PCK Lau, AM Berghuis Journal of the American Chemical Society 134 (18), 7788-7795, 2012 | 113 | 2012 |
| Lactone-bound structures of cyclohexanone monooxygenase provide insight into the stereochemistry of catalysis BJ Yachnin, MB McEvoy, RJD MacCuish, KL Morley, PCK Lau, ... ACS chemical biology 9 (12), 2843-2851, 2014 | 53 | 2014 |
| Multiple conformers in active site of human dihydrofolate reductase F31R/Q35E double mutant suggest structural basis for methotrexate resistance JP Volpato, BJ Yachnin, J Blanchet, V Guerrero, L Poulin, E Fossati, ... Journal of Biological Chemistry 284 (30), 20079-20089, 2009 | 48 | 2009 |
| Characterization of the Redox and Metal Binding Activity of BsSco, a Protein Implicated in the Assembly of Cytochrome c Oxidase I Imriskova-Sosova, D Andrews, K Yam, D Davidson, B Yachnin, BC Hill Biochemistry 44 (51), 16949-16956, 2005 | 38 | 2005 |
| Computational design of a photocontrolled cytosine deaminase KM Blacklock, BJ Yachnin, GA Woolley, SD Khare Journal of the American Chemical Society 140 (1), 14-17, 2018 | 32 | 2018 |
| The role of conformational flexibility in Baeyer-Villiger monooxygenase catalysis and structure BJ Yachnin, PCK Lau, AM Berghuis Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1864 (12), 1641-1648, 2016 | 29 | 2016 |
| Identification and characterization of hippuristanol-resistant mutants reveals eIF4A1 dependencies within mRNA 5′ leader regions J Steinberger, L Shen, S J. Kiniry, SK Naineni, R Cencic, M Amiri, ... Nucleic Acids Research 48 (17), 9521-9537, 2020 | 27 | 2020 |
| Ensuring scientific reproducibility in bio-macromolecular modeling via extensive, automated benchmarks J Koehler Leman, S Lyskov, SM Lewis, J Adolf-Bryfogle, RF Alford, ... Nature communications 12 (1), 6947, 2021 | 17 | 2021 |
| MHCEpitopeEnergy, a flexible Rosetta-based biotherapeutic deimmunization platform BJ Yachnin, VK Mulligan, SD Khare, C Bailey-Kellogg Journal of chemical information and modeling 61 (5), 2368-2382, 2021 | 14 | 2021 |
| Structure-based design of dimeric bisbenzimidazole inhibitors to an emergent trimethoprim-resistant type II dihydrofolate reductase guides the design of monomeric analogues JL Toulouse, BJ Yachnin, EH Ruediger, D Deon, M Gagnon, ... ACS omega 4 (6), 10056-10069, 2019 | 10 | 2019 |
| In Green Polymer Chemistry: Biocatalysis and Biomaterials; Cheng HN, Gross RA, Eds PCK Lau, H Leisch, BJ Yachnin, IA Mirza, AM Berghuis, H Iwaki, ... ACS Symposium Series 1043, 87, 2010 | 10 | 2010 |
| Novel crystallization conditions for tandem variant R67 DHFR yield a wild-type crystal structure BJ Yachnin, DY Colin, JP Volpato, M Ebert, JN Pelletier, AM Berghuis Acta Crystallographica Section F: Structural Biology and Crystallization …, 2011 | 9 | 2011 |
| Sustained development in Baeyer-Villiger biooxidation technology PCK Lau, H Leisch, BJ Yachnin, IA Mirza, AM Berghuis, H Iwaki, ... Green polymer chemistry: biocatalysis and biomaterials, 343-372, 2010 | 8 | 2010 |
| Engineering carboxypeptidase G2 circular permutations for the design of an autoinhibited enzyme BJ Yachnin, SD Khare Protein Engineering, Design and Selection 30 (4), 321-331, 2017 | 7 | 2017 |
| Massively parallel, computationally guided design of a proenzyme BJ Yachnin, LR Azouz, RE White III, CASA Minetti, DP Remeta, VM Tan, ... Proceedings of the National Academy of Sciences 119 (15), e2116097119, 2022 | 6 | 2022 |
| Comprehensive characterization of ligand‐induced plasticity changes in a dimeric enzyme OM Baettig, K Shi, BJ Yachnin, DL Burk, AM Berghuis The FEBS Journal 283 (16), 3029-3038, 2016 | 3 | 2016 |
| A Bis (imidazole)-based cysteine labeling tool for metalloprotein assembly R Ahmad, AM Tyryshkin, L Xie, WA Hansen, BJ Yachnin, TJ Emge, ... Journal of Inorganic Biochemistry 244, 112206, 2023 | | 2023 |
| Massively Parallel Protein Design to Develop Enzymes for Next‐Generation Chemotherapy BJ Yachnin, R White, L Azouz, JM Drake, SD Khare The FASEB Journal 33 (S1), 472.13-472.13, 2019 | | 2019 |
| Computational Design of a Photosensitized Yeast Cytosine Deaminase for Directed Enzyme-Prodrug Therapy K Blacklock, B Yachnin, GA Woolley, S Khare PROTEIN SCIENCE 27, 122-122, 2018 | | 2018 |
