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David T. Paik
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Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis
RC Wirka, D Wagh, DT Paik, M Pjanic, T Nguyen, CL Miller, R Kundu, ...
Nature Medicine 25 (8), 1280–1289, 2019
5942019
Single-cell RNA sequencing in cardiovascular development, disease and medicine
DT Paik, S Cho, L Tian, HY Chang, JC Wu
Nature Reviews Cardiology 17 (8), 457–473, 2020
2192020
Single-Cell RNA-seq Unveils Unique Transcriptomic Signatures of Organ-Specific Endothelial Cells
DT Paik, L Tian, IM Williams, S Rhee, H Zhang, C Liu, R Mishra, SM Wu, ...
Circulation 142 (19), 1848–1862, 2020
1912020
Patient and Disease–Specific Induced Pluripotent Stem Cells for Discovery of Personalized Cardiovascular Drugs and Therapeutics
DT Paik, M Chandy, JC Wu
Pharmacological Reviews 72 (1), 320-342, 2020
1642020
Autologous iPSC-based vaccines elicit anti-tumor responses in vivo
NG Kooreman, Y Kim, PE de Almeida, V Termglinchan, S Diecke, ...
Cell Stem Cell 22 (4), 501-513. e7, 2018
1642018
Wnt activation and reduced cell-cell contact synergistically induce massive expansion of functional human iPSC-derived cardiomyocytes
JW Buikema, S Lee, WR Goodyer, RG Maas, O Chirikian, G Li, Y Miao, ...
Cell stem cell 27 (1), 50-63. e5, 2020
1532020
Transcriptomic Profiling of the Developing Cardiac Conduction System at Single-Cell Resolution
WR Goodyer, BM Beyersdorf, DT Paik, L Tian, G Li, JW Buikema, ...
Circulation Research 125 (4), 379-397, 2019
1432019
Large-Scale Single-Cell RNA-Seq Reveals Molecular Signatures of Heterogeneous Populations of Human Induced Pluripotent Stem Cell-Derived Endothelial Cells
DT Paik, L Tian, J Lee, N Sayed, IY Chen, S Rhee, JW Rhee, Y Kim, ...
Circulation Research 123 (4), 443-450, 2018
1392018
Generation of quiescent cardiac fibroblasts from human induced pluripotent stem cells for in vitro modeling of cardiac fibrosis
H Zhang, L Tian, M Shen, C Tu, H Wu, M Gu, DT Paik, JC Wu
Circulation Research 125 (5), 552-566, 2019
1292019
Origin of Matrix-Producing Cells That Contribute to Aortic Fibrosis in Hypertension
J Wu, KRC Montaniel, MA Saleh, L Xiao, W Chen, GK Owens, ...
Hypertension 67 (2), 461-468, 2016
882016
Endothelial deletion of Ino80 disrupts coronary angiogenesis and causes congenital heart disease
S Rhee, JI Chung, DA King, G D’amato, DT Paik, A Duan, A Chang, ...
Nature Communications 9 (1), 368, 2018
742018
Wnt10b gain-of-function improves cardiac repair by arteriole formation and attenuation of fibrosis
DT Paik, M Rai, S Ryzhov, LN Sanders, O Aisagbonhi, MJ Funke, ...
Circulation Research 117 (9), 804-816, 2015
732015
Endothelial cells contribute to generation of adult ventricular myocytes during cardiac homeostasis
BA Fioret, JD Heimfeld, DT Paik, AK Hatzopoulos
Cell Reports 8 (1), 229-241, 2014
652014
Single-cell RNA sequencing of human embryonic stem cell differentiation delineates adverse effects of nicotine on embryonic development
H Guo, L Tian, JZ Zhang, T Kitani, DT Paik, WH Lee, JC Wu
Stem Cell Reports 12 (4), 772-786, 2019
572019
SETD7 Drives Cardiac Lineage Commitment through Stage-Specific Transcriptional Activation
J Lee, NY Shao, DT Paik, H Wu, H Guo, V Termglinchan, JM Churko, ...
Cell Stem Cell 22 (3), 428-444. e5, 2018
512018
Endocardial/endothelial angiocrines regulate cardiomyocyte development and maturation and induce features of ventricular non-compaction
S Rhee, DT Paik, JY Yang, D Nagelberg, I Williams, L Tian, R Roth, ...
European Heart Journal 42 (41), 4264-4276, 2021
432021
Modeling secondary iron overload cardiomyopathy with human induced pluripotent stem cell-derived cardiomyocytes
JW Rhee, H Yi, D Thomas, CK Lam, N Belbachir, L Tian, X Qin, J Malisa, ...
Cell reports 32 (2), 2020
332020
Systems-wide approaches in induced pluripotent stem cell models
E Lau, DT Paik, JC Wu
Annual Review of Pathology: Mechanisms of Disease 14 (1), 395-419, 2019
262019
Coordinated Proliferation and Differentiation of Human-Induced Pluripotent Stem Cell-Derived Cardiac Progenitor Cells Depend on Bone Morphogenetic Protein Signaling Regulation …
JB Bylund, LT Trinh, CP Awgulewitsch, DT Paik, C Jetter, R Jha, J Zhang, ...
Stem Cells and Development 26 (9), 678-693, 2017
222017
SGLT2 inhibitor ameliorates endothelial dysfunction associated with the common ALDH2 alcohol flushing variant
H Guo, X Yu, Y Liu, DT Paik, JM Justesen, M Chandy, JWS Jahng, ...
Science translational medicine 15 (680), eabp9952, 2023
202023
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