Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis RC Wirka, D Wagh, DT Paik, M Pjanic, T Nguyen, CL Miller, R Kundu, ... Nature Medicine 25 (8), 1280–1289, 2019 | 594 | 2019 |
Single-cell RNA sequencing in cardiovascular development, disease and medicine DT Paik, S Cho, L Tian, HY Chang, JC Wu Nature Reviews Cardiology 17 (8), 457–473, 2020 | 219 | 2020 |
Single-Cell RNA-seq Unveils Unique Transcriptomic Signatures of Organ-Specific Endothelial Cells DT Paik, L Tian, IM Williams, S Rhee, H Zhang, C Liu, R Mishra, SM Wu, ... Circulation 142 (19), 1848–1862, 2020 | 191 | 2020 |
Patient and Disease–Specific Induced Pluripotent Stem Cells for Discovery of Personalized Cardiovascular Drugs and Therapeutics DT Paik, M Chandy, JC Wu Pharmacological Reviews 72 (1), 320-342, 2020 | 164 | 2020 |
Autologous iPSC-based vaccines elicit anti-tumor responses in vivo NG Kooreman, Y Kim, PE de Almeida, V Termglinchan, S Diecke, ... Cell Stem Cell 22 (4), 501-513. e7, 2018 | 164 | 2018 |
Wnt activation and reduced cell-cell contact synergistically induce massive expansion of functional human iPSC-derived cardiomyocytes JW Buikema, S Lee, WR Goodyer, RG Maas, O Chirikian, G Li, Y Miao, ... Cell stem cell 27 (1), 50-63. e5, 2020 | 153 | 2020 |
Transcriptomic Profiling of the Developing Cardiac Conduction System at Single-Cell Resolution WR Goodyer, BM Beyersdorf, DT Paik, L Tian, G Li, JW Buikema, ... Circulation Research 125 (4), 379-397, 2019 | 143 | 2019 |
Large-Scale Single-Cell RNA-Seq Reveals Molecular Signatures of Heterogeneous Populations of Human Induced Pluripotent Stem Cell-Derived Endothelial Cells DT Paik, L Tian, J Lee, N Sayed, IY Chen, S Rhee, JW Rhee, Y Kim, ... Circulation Research 123 (4), 443-450, 2018 | 139 | 2018 |
Generation of quiescent cardiac fibroblasts from human induced pluripotent stem cells for in vitro modeling of cardiac fibrosis H Zhang, L Tian, M Shen, C Tu, H Wu, M Gu, DT Paik, JC Wu Circulation Research 125 (5), 552-566, 2019 | 129 | 2019 |
Origin of Matrix-Producing Cells That Contribute to Aortic Fibrosis in Hypertension J Wu, KRC Montaniel, MA Saleh, L Xiao, W Chen, GK Owens, ... Hypertension 67 (2), 461-468, 2016 | 88 | 2016 |
Endothelial deletion of Ino80 disrupts coronary angiogenesis and causes congenital heart disease S Rhee, JI Chung, DA King, G D’amato, DT Paik, A Duan, A Chang, ... Nature Communications 9 (1), 368, 2018 | 74 | 2018 |
Wnt10b gain-of-function improves cardiac repair by arteriole formation and attenuation of fibrosis DT Paik, M Rai, S Ryzhov, LN Sanders, O Aisagbonhi, MJ Funke, ... Circulation Research 117 (9), 804-816, 2015 | 73 | 2015 |
Endothelial cells contribute to generation of adult ventricular myocytes during cardiac homeostasis BA Fioret, JD Heimfeld, DT Paik, AK Hatzopoulos Cell Reports 8 (1), 229-241, 2014 | 65 | 2014 |
Single-cell RNA sequencing of human embryonic stem cell differentiation delineates adverse effects of nicotine on embryonic development H Guo, L Tian, JZ Zhang, T Kitani, DT Paik, WH Lee, JC Wu Stem Cell Reports 12 (4), 772-786, 2019 | 57 | 2019 |
SETD7 Drives Cardiac Lineage Commitment through Stage-Specific Transcriptional Activation J Lee, NY Shao, DT Paik, H Wu, H Guo, V Termglinchan, JM Churko, ... Cell Stem Cell 22 (3), 428-444. e5, 2018 | 51 | 2018 |
Endocardial/endothelial angiocrines regulate cardiomyocyte development and maturation and induce features of ventricular non-compaction S Rhee, DT Paik, JY Yang, D Nagelberg, I Williams, L Tian, R Roth, ... European Heart Journal 42 (41), 4264-4276, 2021 | 43 | 2021 |
Modeling secondary iron overload cardiomyopathy with human induced pluripotent stem cell-derived cardiomyocytes JW Rhee, H Yi, D Thomas, CK Lam, N Belbachir, L Tian, X Qin, J Malisa, ... Cell reports 32 (2), 2020 | 33 | 2020 |
Systems-wide approaches in induced pluripotent stem cell models E Lau, DT Paik, JC Wu Annual Review of Pathology: Mechanisms of Disease 14 (1), 395-419, 2019 | 26 | 2019 |
Coordinated Proliferation and Differentiation of Human-Induced Pluripotent Stem Cell-Derived Cardiac Progenitor Cells Depend on Bone Morphogenetic Protein Signaling Regulation … JB Bylund, LT Trinh, CP Awgulewitsch, DT Paik, C Jetter, R Jha, J Zhang, ... Stem Cells and Development 26 (9), 678-693, 2017 | 22 | 2017 |
SGLT2 inhibitor ameliorates endothelial dysfunction associated with the common ALDH2 alcohol flushing variant H Guo, X Yu, Y Liu, DT Paik, JM Justesen, M Chandy, JWS Jahng, ... Science translational medicine 15 (680), eabp9952, 2023 | 20 | 2023 |