Genomic landscape of atypical adenomatous hyperplasia reveals divergent modes to lung adenocarcinoma S Sivakumar, FAS Lucas, TL McDowell, W Lang, L Xu, J Fujimoto, ... Cancer research 77 (22), 6119-6130, 2017 | 101 | 2017 |
Concordance of DNA repair gene mutations in paired primary prostate cancer samples and metastatic tissue or cell-free DNA MT Schweizer, S Sivakumar, H Tukachinsky, I Coleman, N De Sarkar, ... JAMA oncology 7 (9), 1378-1382, 2021 | 61 | 2021 |
Comprehensive pan-cancer genomic landscape of KRAS altered cancers and real-world outcomes in solid tumors JK Lee, S Sivakumar, AB Schrock, R Madison, D Fabrizio, O Gjoerup, ... NPJ Precision Oncology 6 (1), 91, 2022 | 59 | 2022 |
Integrative analysis of a large real-world cohort of small cell lung cancer identifies distinct genetic subtypes and insights into histologic transformation S Sivakumar, JA Moore, M Montesion, R Sharaf, DI Lin, CI Colón, ... Cancer discovery 13 (7), 1572-1591, 2023 | 46 | 2023 |
Large-scale analysis of acquired chromosomal alterations in non-tumor samples from patients with cancer YA Jakubek, K Chang, S Sivakumar, Y Yu, MR Giordano, J Fowler, ... Nature biotechnology 38 (1), 90-96, 2020 | 39 | 2020 |
Histiocytic and dendritic cell sarcomas of hematopoietic origin share targetable genomic alterations distinct from follicular dendritic cell sarcoma LR Massoth, YP Hung, JA Ferry, RP Hasserjian, V Nardi, GP Nielsen, ... The oncologist 26 (7), e1263-e1272, 2021 | 38 | 2021 |
Driver mutations in normal airway epithelium elucidate spatiotemporal resolution of lung cancer H Kadara, S Sivakumar, Y Jakubek, FA San Lucas, W Lang, T McDowell, ... American journal of respiratory and critical care medicine 200 (6), 742-750, 2019 | 27 | 2019 |
Augmented lipocalin-2 is associated with chronic obstructive pulmonary disease and counteracts lung adenocarcinoma development W Treekitkarnmongkol, M Hassane, A Sinjab, K Chang, K Hara, Z Rahal, ... American Journal of Respiratory and Critical Care Medicine 203 (1), 90-101, 2021 | 26 | 2021 |
Strategies for identification of somatic variants using the Ion Torrent deep targeted sequencing platform A Deshpande, W Lang, T McDowell, S Sivakumar, J Zhang, J Wang, ... BMC bioinformatics 19, 1-10, 2018 | 24 | 2018 |
Rapid and powerful detection of subtle allelic imbalance from exome sequencing data with hapLOHseq FA San Lucas, S Sivakumar, S Vattathil, J Fowler, E Vilar, P Scheet Bioinformatics 32 (19), 3015-3017, 2016 | 22 | 2016 |
TBX2 subfamily suppression in lung cancer pathogenesis: a high-potential marker for early detection AA Khalil, S Sivakumar, FA San Lucas, T McDowell, W Lang, K Tabata, ... Oncotarget 8 (40), 68230, 2017 | 21 | 2017 |
Tissue and liquid biopsy profiling reveal convergent tumor evolution and therapy evasion in breast cancer S Sivakumar, DX Jin, H Tukachinsky, K Murugesan, K McGregor, ... Nature Communications 13 (1), 7495, 2022 | 20 | 2022 |
Genome-wide gene expression changes in the normal-appearing airway during the evolution of smoking-associated lung adenocarcinoma J Kantrowitz, A Sinjab, L Xu, TL McDowell, S Sivakumar, W Lang, ... Cancer Prevention Research 11 (4), 237-248, 2018 | 19 | 2018 |
Genomic characterization of thymic epithelial tumors in a real-world dataset K Kurokawa, T Shukuya, RA Greenstein, BG Kaplan, H Wakelee, JS Ross, ... ESMO open 8 (5), 101627, 2023 | 13 | 2023 |
Genomic landscape of allelic imbalance in premalignant atypical adenomatous hyperplasias of the lung S Sivakumar, FA San Lucas, YA Jakubek, TL McDowell, W Lang, ... EBioMedicine 42, 296-303, 2019 | 13 | 2019 |
Biology and Targetability of the Extended Spectrum of PIK3CA Mutations Detected in Breast Carcinoma HS Rugo, K Raskina, AB Schrock, RW Madison, RP Graf, ES Sokol, ... Clinical Cancer Research 29 (6), 1056-1067, 2023 | 12 | 2023 |
Ancestral characterization of the genomic landscape, comprehensive genomic profiling utilization, and treatment patterns may inform disparities in advanced prostate cancer: A … S Sivakumar, JK Lee, JA Moore, J Hopkins, J Newberg, AB Schrock, ... Journal of Clinical Oncology 39 (15_suppl), 5003-5003, 2021 | 12 | 2021 |
Multiple PIK3CA mutation clonality correlates with outcomes in taselisib + fulvestrant-treated ER+/HER2–, PIK3CA-mutated breast cancers KE Hutchinson, JW Chen, HM Savage, TJ Stout, F Schimmoller, J Cortés, ... Genome Medicine 15 (1), 28, 2023 | 11 | 2023 |
Genetic Heterogeneity and Tissue-specific Patterns of Tumors with Multiple PIK3CA Mutations S Sivakumar, DX Jin, R Rathod, J Ross, LC Cantley, M Scaltriti, JW Chen, ... Clinical Cancer Research 29 (6), 1125-1136, 2023 | 11 | 2023 |
Intra-patient stability of tumor mutational burden from tissue biopsies at different time points in advanced cancers TV Pham, AM Goodman, S Sivakumar, G Frampton, R Kurzrock Genome Medicine 13, 1-9, 2021 | 11 | 2021 |