Detection of microcystins, a blue-green algal hepatotoxin, in drinking water sampled in Haimen and Fusui, endemic areas of primary liver cancer in China, by highly sensitive … Y Ueno, S Nagata, T Tsutsumi, A Hasegawa, MF Watanabe, HD Park, ... Oxford University Press 17 (6), 1317-1321, 1996 | 1036 | 1996 |
Two Species of Human CRK cDNA Encode Proteins with Distinct Biological Activities M Matsuda, S Tanaka, S Nagata, A Kojima, T Kurata, M Shibuya Molecular and cellular biology 12 (8), 3482-3489, 1992 | 353 | 1992 |
Site-specific chemical modification with polyethylene glycol of recombinant immunotoxin anti-Tac (Fv)-PE38 (LMB-2) improves antitumor activity and reduces animal toxicity and … Y Tsutsumi, M Onda, S Nagata, B Lee, RJ Kreitman, I Pastan Proceedings of the National Academy of Sciences 97 (15), 8548-8553, 2000 | 323 | 2000 |
Site-specific PEGylation of a lysine-deficient TNF-α with full bioactivity Y Yamamoto, Y Tsutsumi, Y Yoshioka, T Nishibata, K Kobayashi, ... Nature biotechnology 21 (5), 546-552, 2003 | 267 | 2003 |
SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling M Shinohara, Y Terada, A Iwamatsu, A Shinohara, N Mochizuki, ... Nature 416 (6882), 759-763, 2002 | 261 | 2002 |
Isolation of anti-CD22 Fv with high affinity by Fv display on human cells M Ho, S Nagata, I Pastan Proceedings of the National Academy of Sciences 103 (25), 9637-9642, 2006 | 254 | 2006 |
An immunotoxin with greatly reduced immunogenicity by identification and removal of B cell epitopes M Onda, R Beers, L Xiang, S Nagata, Q Wang, I Pastan Proceedings of the National Academy of Sciences 105 (32), 11311-11316, 2008 | 231 | 2008 |
Detection and Identification of Metabolites of Microcystins Formed in Vivo in Mouse and Rat Livers F Kondo, H Matsumoto, S Yamada, N Ishikawa, E Ito, S Nagata, Y Ueno, ... Chemical Research in Toxicology 9 (8), 1355-1359, 1996 | 218 | 1996 |
Acute oral toxicity of microcystin‐LR, a cyanobacterial hepatotoxin, in mice T Yoshida, Y Makita, S Nagata, T Tsutsumi, F Yoshida, M Sekijima, ... Natural toxins 5 (3), 91-95, 1997 | 211 | 1997 |
Induction of apoptosis by T‐2 toxin and other natural toxins in HL‐60 human promyelotic leukemia cells Y Ueno, K Umemori, EC Niimi, SI Tanuma, S Nagata, M Sugamata, ... Natural toxins 3 (3), 129-137, 1995 | 195 | 1995 |
Novel monoclonal antibodies against microcystin and their protective activity for hepatotoxicity S Nagata, H Soutome, T Tsutsumi, A Hasegawa, M Sekijima, M Sugamata, ... Natural toxins 3 (2), 78-86, 1995 | 191 | 1995 |
Dual control of neurite outgrowth by STAT3 and MAP kinase in PC12 cells stimulated with interleukin‐6 S Ihara, K Nakajima, T Fukada, M Hibi, S Nagata, T Hirano, Y Fukui The EMBO journal, 1997 | 175 | 1997 |
Microinjection of activated phosphatidylinositol-3 kinase induces process outgrowth in rat PC12 cells through the Rac-JNK signal transduction pathway Y Kita, KD Kimura, M Kobayashi, S Ihara, K Kaibuchi, S Kuroda, M Ui, ... Journal of cell science 111 (7), 907-915, 1998 | 160 | 1998 |
Synthesis of a poly (vinylpyrrolidone-co-dimethyl maleic anhydride) co-polymer and its application for renal drug targeting H Kamada, Y Tsutsumi, K Sato-Kamada, Y Yamamoto, Y Yoshioka, ... nature biotechnology 21 (4), 399-404, 2003 | 150 | 2003 |
Evidence that a phosphatidylinositol 3, 4, 5-trisphosphate-binding protein can function in nucleus K Tanaka, K Horiguchi, T Yoshida, M Takeda, H Fujisawa, K Takeuchi, ... Journal of Biological Chemistry 274 (7), 3919-3922, 1999 | 150 | 1999 |
Coexpression of TIGIT and FCRL3 identifies Helios+ human memory regulatory T cells K Bin Dhuban, E d’Hennezel, E Nashi, A Bar-Or, S Rieder, EM Shevach, ... The Journal of Immunology 194 (8), 3687-3696, 2015 | 149 | 2015 |
Expression of a constitutively active phosphatidylinositol 3-kinase induces process formation in rat PC12 cells: use of Cre/loxP recombination system M Kobayashi, S Nagata, Y Kita, N Nakatsu, S Ihara, K Kaibuchi, S Kuroda, ... Journal of Biological Chemistry 272 (26), 16089-16092, 1997 | 144 | 1997 |
Characterization of the B cell epitopes associated with a truncated form of Pseudomonas exotoxin (PE38) used to make immunotoxins for the treatment of cancer patients M Onda, S Nagata, DJ FitzGerald, R Beers, RJ Fisher, JJ Vincent, B Lee, ... The Journal of Immunology 177 (12), 8822-8834, 2006 | 135 | 2006 |
Megakaryocyte potentiation factor cleaved from mesothelin precursor is a useful tumor marker in the serum of patients with mesothelioma M Onda, S Nagata, M Ho, TK Bera, R Hassan, RH Alexander, I Pastan Clinical cancer research 12 (14), 4225-4231, 2006 | 129 | 2006 |
Survey of microcystins in environmental water by a highly sensitive immunoassay based on monoclonal antibody Y Ueno, S Nagata, T Tsutsumi, A Hasegawa, F Yoshida, M Suttajit, ... Natural toxins 4 (6), 271-276, 1996 | 127 | 1996 |