Directed evolution of CRISPR-Cas9 to increase its specificity JK Lee, E Jeong, J Lee, M Jung, E Shin, Y Kim, K Lee, I Jung, D Kim, ... Nature communications 9 (1), 3048, 2018 | 530 | 2018 |
Autophagy regulates homeostasis of pluripotency-associated proteins in hESCs YH Cho, KM Han, D Kim, J Lee, SH Lee, KW Choi, J Kim, YM Han Stem Cells 32 (2), 424-435, 2014 | 70 | 2014 |
Sniper2L is a high-fidelity Cas9 variant with high activity Y Kim, N Kim, I Okafor, S Choi, S Min, J Lee, SM Bae, K Choi, J Choi, ... Nature chemical biology 19 (8), 972-980, 2023 | 25 | 2023 |
Using Sniper-Cas9 to minimize off-target effects of CRISPR-Cas9 without the loss of on-target activity via directed evolution J Lee, M Jung, E Jeong, JK Lee JoVE (Journal of Visualized Experiments), e59202, 2019 | 23 | 2019 |
Ascl1 and Ngn2 convert mouse embryonic stem cells to neurons via functionally distinct paths G Vainorius, M Novatchkova, G Michlits, JC Baar, C Raupach, J Lee, ... Nature Communications 14 (1), 5341, 2023 | 13 | 2023 |
Dysregulated ECM remodeling proteins lead to aberrant osteogenesis of Costello syndrome iPSCs JB Choi, J Lee, M Kang, B Kim, Y Ju, HS Do, HW Yoo, BH Lee, YM Han Stem Cell Reports 16 (8), 1985-1998, 2021 | 11 | 2021 |
CRISPR-StAR enables high-resolution genetic screening in complex in vivo models ECH Uijttewaal, J Lee, AC Sell, N Botay, G Vainorius, M Novatchkova, ... Nature Biotechnology, 1-13, 2024 | | 2024 |
Target-specific crispr mutant YH Kim, MH Jung, LEE Joonsun, E Shin, KI Lee, S Kim, LEE JeongJoon US Patent App. 17/880,160, 2023 | | 2023 |
Target-specific CRISPR mutant YH Kim, MH Jung, LEE Joonsun, E Shin, KI Lee, S Kim, LEE JeongJoon US Patent 11,441,135, 2022 | | 2022 |