| The role of DNA methylation in mammalian epigenetics PA Jones, D Takai Science 293 (5532), 1068-1070, 2001 | 2692 | 2001 |
| Comprehensive analysis of CpG islands in human chromosomes 21 and 22 D Takai, PA Jones Proceedings of the national academy of sciences 99 (6), 3740-3745, 2002 | 2073 | 2002 |
| Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome G Liang, JCY Lin, V Wei, C Yoo, JC Cheng, CT Nguyen, DJ Weisenberger, ... Proceedings of the National Academy of Sciences 101 (19), 7357-7362, 2004 | 648 | 2004 |
| The CpG island searcher: a new WWW resource D Takai, PA Jones In silico biology 3 (3), 235-240, 2003 | 429 | 2003 |
| Role of nucleosomal occupancy in the epigenetic silencing of the MLH1 CpG island JC Lin, S Jeong, G Liang, D Takai, M Fatemi, YC Tsai, G Egger, ... Cancer cell 12 (5), 432-444, 2007 | 265 | 2007 |
| Establishment of conditional vectors for hairpin siRNA knockdowns S Matsukura, PA Jones, D Takai Nucleic acids research 31 (15), e77-e77, 2003 | 255 | 2003 |
| Large scale mapping of methylcytosines in CTCF-binding sites in the human H19 promoter and aberrant hypomethylation in human bladder cancer D Takai, FA Gonzales, YC Tsai, MJ Thayer, PA Jones Human molecular genetics 10 (23), 2619-2626, 2001 | 251 | 2001 |
| Hypomethylation of LINE1 retrotransposon in human hepatocellular carcinomas, but not in surrounding liver cirrhosis D Takai, Y Yagi, N Habib, T Sugimura, T Ushijima Japanese journal of clinical oncology 30 (7), 306-309, 2000 | 135 | 2000 |
| Genome structure‐based screening identified epigenetically silenced microRNA associated with invasiveness in non‐small‐cell lung cancer K Watanabe, N Emoto, E Hamano, M Sunohara, M Kawakami, H Kage, ... International journal of cancer 130 (11), 2580-2590, 2012 | 122 | 2012 |
| Origins of bidirectional promoters: computational analyses of intergenic distance in the human genome D Takai, PA Jones Molecular Biology and Evolution 21 (3), 463-467, 2004 | 100 | 2004 |
| Expression of PRMT5 in lung adenocarcinoma and its significance in epithelial-mesenchymal transition R Ibrahim, D Matsubara, W Osman, T Morikawa, A Goto, S Morita, ... Human pathology 45 (7), 1397-1405, 2014 | 97 | 2014 |
| The induction of H3K9 methylation by PIWIL4 at the p16Ink4a locus K Sugimoto, H Kage, N Aki, A Sano, H Kitagawa, T Nagase, Y Yatomi, ... Biochemical and biophysical research communications 359 (3), 497-502, 2007 | 93 | 2007 |
| Identification and characterization of alternatively spliced variants of DNA methyltransferase 3a in mammalian cells DJ Weisenberger, M Velicescu, MA Preciado-Lopez, FA Gonzales, ... Gene 298 (1), 91-99, 2002 | 87 | 2002 |
| High-grade lung adenocarcinoma with fetal lung–like morphology: clinicopathologic, immunohistochemical, and molecular analyses of 17 cases S Morita, A Yoshida, A Goto, S Ota, K Tsuta, K Yokozawa, H Asamura, ... The American journal of surgical pathology 37 (6), 924-932, 2013 | 86 | 2013 |
| MicroRNA-21 in cancer-associated fibroblasts supports lung adenocarcinoma progression A Kunita, S Morita, TU Irisa, A Goto, T Niki, D Takai, J Nakajima, ... Scientific reports 8 (1), 8838, 2018 | 76 | 2018 |
| Alternative polyadenylation is associated with lower expression of PABPN 1 and poor prognosis in non‐small cell lung cancer J Ichinose, K Watanabe, A Sano, T Nagase, J Nakajima, M Fukayama, ... Cancer Science 105 (9), 1135-1141, 2014 | 74 | 2014 |
| Comprehensive assay for the molecular profiling of cancer by target enrichment from formalin‐fixed paraffin‐embedded specimens S Kohsaka, K Tatsuno, T Ueno, M Nagano, A Shinozaki‐Ushiku, T Ushiku, ... Cancer science 110 (4), 1464-1479, 2019 | 69 | 2019 |
| Silencing of HTR1B and reduced expression of EDN1 in human lung cancers, revealed by methylation-sensitive representational difference analysis D Takai, Y Yagi, K Wakazono, N Ohishi, Y Morita, T Sugimura, T Ushijima Oncogene 20 (51), 7505-7513, 2001 | 69 | 2001 |
| Methylation‐Sensitive Representational Difference Analysis and Its Application to Cancer Research A Kaneda, D Takai, M Kaminishi, E Okochi, T Ushijima Annals of the New York Academy of Sciences 983 (1), 131-141, 2003 | 66 | 2003 |
| Identification of G0S2 as a gene frequently methylated in squamous lung cancer by combination of in silico and experimental approaches M Kusakabe, T Kutomi, K Watanabe, N Emoto, N Aki, H Kage, E Hamano, ... International journal of cancer 126 (8), 1895-1902, 2010 | 64 | 2010 |
