| An allosteric modulator to control endogenous G protein-coupled receptors with light S Pittolo, X Gomez-Santacana, K Eckelt, X Rovira, J Dalton, C Goudet, ... Nature chemical biology 10 (10), 813-815, 2014 | 172 | 2014 |
| An evaluation of automated homology modelling methods at low target–template sequence similarity JAR Dalton, RM Jackson Bioinformatics 23 (15), 1901-1908, 2007 | 130 | 2007 |
| New model of cystic fibrosis transmembrane conductance regulator proposes active channel-like conformation J Dalton, O Kalid, M Schushan, N Ben-Tal, J Villà-Freixa Journal of chemical information and modeling 52 (7), 1842-1853, 2012 | 86 | 2012 |
| Illuminating phenylazopyridines to photoswitch metabotropic glutamate receptors: from the flask to the animals X Gómez-Santacana, S Pittolo, X Rovira, M Lopez, C Zussy, JAR Dalton, ... ACS central science 3 (1), 81-91, 2017 | 76 | 2017 |
| Allosteric control of an asymmetric transduction in a G protein-coupled receptor heterodimer J Liu, Z Zhang, D Moreno-Delgado, JAR Dalton, X Rovira, A Trapero, ... Elife 6, e26985, 2017 | 58 | 2017 |
| GNAO1 encephalopathy: further delineation of a severe neurodevelopmental syndrome affecting females A Marcé-Grau, J Dalton, J López-Pisón, MC García-Jiménez, ... Orphanet journal of rare diseases 11, 1-9, 2016 | 48 | 2016 |
| Quantifying conformational changes in GPCRs: glimpse of a common functional mechanism JAR Dalton, I Lans, J Giraldo BMC bioinformatics 16, 1-15, 2015 | 48 | 2015 |
| Artificial intelligence: a novel approach for drug discovery Ó Díaz, JAR Dalton, J Giraldo Trends in pharmacological sciences 40 (8), 550-551, 2019 | 47 | 2019 |
| Structural insights into positive and negative allosteric regulation of a G protein-coupled receptor through protein-lipid interactions A Bruzzese, C Gil, JAR Dalton, J Giraldo Scientific reports 8 (1), 4456, 2018 | 47 | 2018 |
| Structural assessment of agonist efficacy in the μ-opioid receptor: morphine and fentanyl elicit different activation patterns A Ricarte, JAR Dalton, J Giraldo Journal of chemical information and modeling 61 (3), 1251-1274, 2021 | 46 | 2021 |
| Calculation of helix packing angles in protein structures JAR Dalton, I Michalopoulos, DR Westhead Bioinformatics 19 (10), 1298-1299, 2003 | 38 | 2003 |
| Distinct Dopamine D2 Receptor Antagonists Differentially Impact D2 Receptor Oligomerization E Wouters, AR Marín, JAR Dalton, J Giraldo, C Stove International journal of molecular sciences 20 (7), 1686, 2019 | 32 | 2019 |
| Homology-modelling protein–ligand interactions: allowing for ligand-induced conformational change JAR Dalton, RM Jackson Journal of molecular biology 399 (4), 645-661, 2010 | 32 | 2010 |
| Computational analysis of negative and positive allosteric modulator binding and function in metabotropic glutamate receptor 5 (in) activation JAR Dalton, X Gomez-Santacana, A Llebaria, J Giraldo Journal of chemical information and modeling 54 (5), 1476-1487, 2014 | 28 | 2014 |
| Revealing the mechanism of agonist-mediated cannabinoid receptor 1 (CB1) activation and phospholipid-mediated allosteric modulation Ó Díaz, JAR Dalton, J Giraldo Journal of Medicinal Chemistry 62 (11), 5638-5654, 2019 | 25 | 2019 |
| Insights into adenosine A2A receptor activation through cooperative modulation of agonist and allosteric lipid interactions A Bruzzese, JAR Dalton, J Giraldo PLoS computational biology 16 (4), e1007818, 2020 | 24 | 2020 |
| Synthesis toward Bivalent Ligands for the Dopamine D2 and Metabotropic Glutamate 5 Receptors M Qian, E Wouters, JAR Dalton, MDP Risseeuw, RAJ Crans, C Stove, ... Journal of Medicinal Chemistry 61 (18), 8212-8225, 2018 | 23 | 2018 |
| Rational design of a peptide capture agent for CXCL8 based on a model of the CXCL8: CXCR1 complex D Helmer, I Rink, JAR Dalton, K Brahm, M Jöst, TM Nargang, W Blum, ... RSC advances 5 (33), 25657-25668, 2015 | 22 | 2015 |
| Shining light on an mGlu5 photoswitchable NAM: a theoretical perspective J AR Dalton, I Lans, X Rovira, F Malhaire, X Gómez-Santacana, S Pittolo, ... Current neuropharmacology 14 (5), 441-454, 2016 | 20 | 2016 |
| Helix 3 acts as a conformational hinge in Class A GPCR activation: An analysis of interhelical interaction energies in crystal structures I Lans, JAR Dalton, J Giraldo Journal of structural biology 192 (3), 545-553, 2015 | 19 | 2015 |
