| The methionine-aromatic motif plays a unique role in stabilizing protein structure CC Valley, A Cembran, JD Perlmutter, AK Lewis, NP Labello, J Gao, ... Journal of Biological Chemistry 287 (42), 34979-34991, 2012 | 328 | 2012 |
| Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces death receptor 5 networks that are highly organized CC Valley, AK Lewis, DJ Mudaliar, JD Perlmutter, AR Braun, CB Karim, ... Journal of Biological Chemistry 287 (25), 21265-21278, 2012 | 108 | 2012 |
| An innovative high-throughput screening approach for discovery of small molecules that inhibit TNF receptors CH Lo, N Vunnam, AK Lewis, TL Chiu, BE Brummel, TM Schaaf, BD Grant, ... SLAS DISCOVERY: Advancing Life Sciences R&D 22 (8), 950-961, 2017 | 65 | 2017 |
| Oxidation increases the strength of the methionine-aromatic interaction AK Lewis, KM Dunleavy, TL Senkow, C Her, BT Horn, MA Jersett, ... Nature chemical biology 12 (10), 860-866, 2016 | 63 | 2016 |
| TNFR1 signaling is associated with backbone conformational changes of receptor dimers consistent with overactivation in the R92Q TRAPS mutant AK Lewis, CC Valley, JN Sachs Biochemistry 51 (33), 6545-6555, 2012 | 55 | 2012 |
| Modularly assembled porous cell-laden hydrogels B Liu, Y Liu, AK Lewis, W Shen Biomaterials 31 (18), 4918-4925, 2010 | 55 | 2010 |
| Physical hydrogels photo-cross-linked from self-assembled macromers for potential use in tissue engineering B Liu, AK Lewis, W Shen Biomacromolecules 10 (12), 3182-3187, 2009 | 40 | 2009 |
| Open and closed conformations of the isolated transmembrane domain of death receptor 5 support a new model of activation AK Lewis, ZM James, JE McCaffrey, AR Braun, CB Karim, DD Thomas, ... Biophysical journal 106 (6), L21-L24, 2014 | 28 | 2014 |
| Piecing it together: Unraveling the elusive structure-function relationship in single-pass membrane receptors CC Valley, AK Lewis, JN Sachs Biochimica et Biophysica Acta (BBA)-Biomembranes 1859 (9), 1398-1416, 2017 | 24 | 2017 |
| Death receptor 5 networks require membrane cholesterol for proper structure and function AK Lewis, CC Valley, SL Peery, B Brummel, AR Braun, CB Karim, ... Journal of molecular biology 428 (24), 4843-4855, 2016 | 21 | 2016 |
| Minimal Nucleation State of α-Synuclein Is Stabilized by Dynamic Threonine–Water Networks TD Romo, AK Lewis, AR Braun, A Grossfield, JN Sachs ACS chemical neuroscience 8 (9), 1859-1864, 2017 | 15 | 2017 |
| Death receptor 5 activation is energetically coupled to opening of the transmembrane domain dimer N Vunnam, CK Campbell-Bezat, AK Lewis, JN Sachs Biophysical journal 113 (2), 381-392, 2017 | 12 | 2017 |
| Engineered protein-small molecule conjugates empower selective enzyme inhibition AK Lewis, A Harthorn, SM Johnson, RR Lobb, BJ Hackel Cell chemical biology 29 (2), 328-338. e4, 2022 | 11 | 2022 |
| EFFECT OF PARATHYROID HORMONE ON CERTAIN SIGNS AND SYMPTOMS IN TUBERCULOSIS: PRELIMINARY REPORT B Gordon, JL ROARK, AK LEWIS Journal of the American Medical Association 86 (22), 1683-1686, 1926 | 3 | 1926 |
| Inhibition of tumor necrosis factor receptor 1 signaling by small molecules CH Lo, N Vunnam, A Lewis, TL Chiu, B Brummel, T Schaaf, B Grant, ... The FASEB Journal 31, 609.11-609.11, 2017 | 1 | 2017 |
| Oxidation Increases the Strength of the Methionine-Aromatic Interaction AK Lewis, A Cembran, TL Senkow, R Mahling, GT Perell, MR McCarthy, ... Biophysical Journal 108 (2), 17a, 2015 | 1 | 2015 |
| Oxidative Stress Modulates Bioactivity of Lymphotoxin, but not TNF, Through Site-Specific Oxidation of Methionine Residues AK Lewis, JN Sachs Biophysical Journal 106 (2), 251a-252a, 2014 | 1 | 2014 |
| Computational Studies of Alpha-Synuclein Fibril Formation and Stability AH Beaven, TD Romo, AK Lewis, AR Braun, A Grossfield, JN Sachs Biophysical Journal 114 (3), 230a, 2018 | | 2018 |
| Manipulations of the TNF-Receptor Affinity and Oligomerization Characterized by Fluorescence Lifetime Measurements CH Lo, A Lewis, T Schaaf, P Bawaskar, N Vunnam, K Peterson, ... Biophysical Journal 110 (3), 490a, 2016 | | 2016 |
| Investigating the Role of Transmembrane Domain Cysteine Residues in the Organization of TNF Receptors TL Senkow, AK Lewis, JN Sachs Biophysical Journal 110 (3), 227a, 2016 | | 2016 |
Christopher C. ValleyBio-Techne在 bio-techne.com 的电子邮件经过验证
Christopher C. ValleyBio-Techne在 bio-techne.com 的电子邮件经过验证
Alessandro CembranAssistant Professor, University of Minnesota Duluth在 d.umn.edu 的电子邮件经过验证