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Hernan Huerta Castro
Hernan Huerta Castro
Postdoctoral Researcher at Center for Geroscience, Mental Health and Metabolism, GERO
在 mayor.cl 的电子邮件经过验证 - 首页
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Cancer cells with defective oxidative phosphorylation require endoplasmic reticulum–to–mitochondria Ca2+ transfer for survival
C Cardenas, A Lovy, E Silva-Pavez, F Urra, C Mizzoni, ...
Science signaling 13 (640), eaay1212, 2020
622020
Unfolded protein response IRE1/XBP1 signaling is required for healthy mammalian brain aging
F Cabral‐Miranda, G Tamburini, G Martinez, AO Ardiles, DB Medinas, ...
The EMBO Journal 41 (22), e111952, 2022
382022
Enhanced caveolin-1 expression increases migration, anchorage-independent growth and invasion of endometrial adenocarcinoma cells
N Diaz-Valdivia, D Bravo, H Huerta, S Henriquez, F Gabler, M Vega, ...
BMC cancer 15, 1-11, 2015
372015
Colon cancer cell invasion is promoted by protein kinase CK2 through increase of endothelin-converting enzyme-1c protein stability
I Niechi, E Silva, P Cabello, H Huerta, V Carrasco, P Villar, LR Cataldo, ...
Oncotarget 6 (40), 42749, 2015
332015
Upregulation of PIR gene expression induced by human papillomavirus E6 and E7 in epithelial oral and cervical cells
D Carrillo, JP Munoz, H Huerta, G Leal, A Corvalán, O León, GM Calaf, ...
Open biology 7 (11), 170111, 2017
262017
SK channel activation potentiates auranofin-induced cell death in glio-and neuroblastoma cells
IE Krabbendam, B Honrath, L Bothof, E Silva-Pavez, H Huerta, ...
Biochemical Pharmacology 171, 113714, 2020
222020
Endothelin‐converting enzyme‐1c promotes stem cell traits and aggressiveness in colorectal cancer cells
P Pérez‐Moreno, S Indo, I Niechi, H Huerta, P Cabello, L Jara, F Aguayo, ...
Molecular Oncology 14 (2), 347-362, 2020
182020
Control of mammalian brain aging by the unfolded protein response (UPR)
F Cabral-Miranda, G Tamburini, G Martinez, D Medinas, Y Gerakis, ...
Biorxiv, 2020.04. 13.039172, 2020
162020
Necroptosis inhibition counteracts neurodegeneration, memory decline, and key hallmarks of aging, promoting brain rejuvenation
MS Arrázola, M Lira, F Véliz‐Valverde, G Quiroz, S Iqbal, SL Eaton, ...
Aging cell 22 (5), e13814, 2023
132023
Scalable total synthesis, IP3R inhibitory activity of desmethylxestospongin B, and effect on mitochondrial function and cancer cell survival
M Podunavac, AK Mailyan, JJ Jackson, A Lovy, P Farias, H Huerta, ...
Angewandte Chemie 133 (20), 11378-11382, 2021
132021
The Ski protein is involved in the transformation pathway of aurora kinase A
S Rivas, R Armisén, DA Rojas, E Maldonado, H Huerta, JC Tapia, ...
Journal of Cellular Biochemistry 117 (2), 334-343, 2016
72016
Ketogenic diet administration later in life improves memory by modifying the synaptic cortical proteome via the PKA signaling pathway in aging mice
D Acuña-Catalán, S Shah, C Wehrfritz, M Nomura, A Acevedo, C Olmos, ...
Cell Reports Medicine 5 (6), 2024
62024
Transactivation activity and nucleocytoplasmic transport of β-catenin are independently regulated by its C-terminal end
JL Maturana, I Niechi, E Silva, H Huerta, R Cataldo, S Härtel, LF Barros, ...
Gene 573 (1), 115-122, 2015
42015
Necroptosis inhibition counteracts axonal degeneration, cognitive decline and key hallmarks of aging, promoting brain rejuvenation
MS Arrázola, M Lira, G Quiroz, S Iqbal, SL Eaton, RA Kline, DJ Lamont, ...
bioRxiv, 2021.11. 10.468052, 2021
22021
Cancer cells with defective oxidative phosphorylation require endoplasmic reticulum–to–mitochondria Ca 2 transfer for survival
C Cardenas, A Lovy, E Silva-Pavez, F Urra, C Mizzoni, ...
12020
The IP3R inhibitor desmethylxestospongin B reduces tumor cell migration, invasion and metastasis by impairing lysosome acidification and β1-integrin recycling
G Bustos, U Ahumada-Castro, E Silva-Pavez, H Huerta, A Puebla, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1871 (1), 167557, 2025
2025
Calcium (Ca2+) fluxes at Mitochondria-ER Contact Sites (MERCS) are a new target of senolysis in Therapy-Induced Senescence (TIS).
A Puebla-Huerta, H Huerta, C Quezada-Gutierrez, P Morgado-Caceres, ...
bioRxiv, 2024.03. 31.587471, 2024
2024
P296 Copper nanoparticles ameliorates Dysferlinopathy phenotype by promoting mitochondrial homeostasis
H Huerta, C González, P Morgado-Cáceres, E Salas-Huenuleo, ...
Neuromuscular Disorders 33, S117, 2023
2023
Ketogenic diet administration later in life improves memory and regulates the synaptic cortical proteome through the cAMP/PKA signaling pathway in aging mice
D Acuña-Catalán, S Shah, C Wehrfritz, M Nomura, A Acevedo, C Olmos, ...
bioRxiv, 2023.09. 07.556691, 2023
2023
Unfolded protein response IRE1/XBP1 signaling is required for healthy mammalian brain aging
C Ibaceta-Gonzalez, CM Sabusap, F Bermedo-Garcia, P Mujica, ...
The EMBO Journal, e111952, 2022
2022
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