Cancer cells with defective oxidative phosphorylation require endoplasmic reticulum–to–mitochondria Ca2+ transfer for survival C Cardenas, A Lovy, E Silva-Pavez, F Urra, C Mizzoni, ... Science signaling 13 (640), eaay1212, 2020 | 62 | 2020 |
Unfolded protein response IRE1/XBP1 signaling is required for healthy mammalian brain aging F Cabral‐Miranda, G Tamburini, G Martinez, AO Ardiles, DB Medinas, ... The EMBO Journal 41 (22), e111952, 2022 | 38 | 2022 |
Enhanced caveolin-1 expression increases migration, anchorage-independent growth and invasion of endometrial adenocarcinoma cells N Diaz-Valdivia, D Bravo, H Huerta, S Henriquez, F Gabler, M Vega, ... BMC cancer 15, 1-11, 2015 | 37 | 2015 |
Colon cancer cell invasion is promoted by protein kinase CK2 through increase of endothelin-converting enzyme-1c protein stability I Niechi, E Silva, P Cabello, H Huerta, V Carrasco, P Villar, LR Cataldo, ... Oncotarget 6 (40), 42749, 2015 | 33 | 2015 |
Upregulation of PIR gene expression induced by human papillomavirus E6 and E7 in epithelial oral and cervical cells D Carrillo, JP Munoz, H Huerta, G Leal, A Corvalán, O León, GM Calaf, ... Open biology 7 (11), 170111, 2017 | 26 | 2017 |
SK channel activation potentiates auranofin-induced cell death in glio-and neuroblastoma cells IE Krabbendam, B Honrath, L Bothof, E Silva-Pavez, H Huerta, ... Biochemical Pharmacology 171, 113714, 2020 | 22 | 2020 |
Endothelin‐converting enzyme‐1c promotes stem cell traits and aggressiveness in colorectal cancer cells P Pérez‐Moreno, S Indo, I Niechi, H Huerta, P Cabello, L Jara, F Aguayo, ... Molecular Oncology 14 (2), 347-362, 2020 | 18 | 2020 |
Control of mammalian brain aging by the unfolded protein response (UPR) F Cabral-Miranda, G Tamburini, G Martinez, D Medinas, Y Gerakis, ... Biorxiv, 2020.04. 13.039172, 2020 | 16 | 2020 |
Necroptosis inhibition counteracts neurodegeneration, memory decline, and key hallmarks of aging, promoting brain rejuvenation MS Arrázola, M Lira, F Véliz‐Valverde, G Quiroz, S Iqbal, SL Eaton, ... Aging cell 22 (5), e13814, 2023 | 13 | 2023 |
Scalable total synthesis, IP3R inhibitory activity of desmethylxestospongin B, and effect on mitochondrial function and cancer cell survival M Podunavac, AK Mailyan, JJ Jackson, A Lovy, P Farias, H Huerta, ... Angewandte Chemie 133 (20), 11378-11382, 2021 | 13 | 2021 |
The Ski protein is involved in the transformation pathway of aurora kinase A S Rivas, R Armisén, DA Rojas, E Maldonado, H Huerta, JC Tapia, ... Journal of Cellular Biochemistry 117 (2), 334-343, 2016 | 7 | 2016 |
Ketogenic diet administration later in life improves memory by modifying the synaptic cortical proteome via the PKA signaling pathway in aging mice D Acuña-Catalán, S Shah, C Wehrfritz, M Nomura, A Acevedo, C Olmos, ... Cell Reports Medicine 5 (6), 2024 | 6 | 2024 |
Transactivation activity and nucleocytoplasmic transport of β-catenin are independently regulated by its C-terminal end JL Maturana, I Niechi, E Silva, H Huerta, R Cataldo, S Härtel, LF Barros, ... Gene 573 (1), 115-122, 2015 | 4 | 2015 |
Necroptosis inhibition counteracts axonal degeneration, cognitive decline and key hallmarks of aging, promoting brain rejuvenation MS Arrázola, M Lira, G Quiroz, S Iqbal, SL Eaton, RA Kline, DJ Lamont, ... bioRxiv, 2021.11. 10.468052, 2021 | 2 | 2021 |
Cancer cells with defective oxidative phosphorylation require endoplasmic reticulum–to–mitochondria Ca 2 transfer for survival C Cardenas, A Lovy, E Silva-Pavez, F Urra, C Mizzoni, ... | 1 | 2020 |
The IP3R inhibitor desmethylxestospongin B reduces tumor cell migration, invasion and metastasis by impairing lysosome acidification and β1-integrin recycling G Bustos, U Ahumada-Castro, E Silva-Pavez, H Huerta, A Puebla, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1871 (1), 167557, 2025 | | 2025 |
Calcium (Ca2+) fluxes at Mitochondria-ER Contact Sites (MERCS) are a new target of senolysis in Therapy-Induced Senescence (TIS). A Puebla-Huerta, H Huerta, C Quezada-Gutierrez, P Morgado-Caceres, ... bioRxiv, 2024.03. 31.587471, 2024 | | 2024 |
P296 Copper nanoparticles ameliorates Dysferlinopathy phenotype by promoting mitochondrial homeostasis H Huerta, C González, P Morgado-Cáceres, E Salas-Huenuleo, ... Neuromuscular Disorders 33, S117, 2023 | | 2023 |
Ketogenic diet administration later in life improves memory and regulates the synaptic cortical proteome through the cAMP/PKA signaling pathway in aging mice D Acuña-Catalán, S Shah, C Wehrfritz, M Nomura, A Acevedo, C Olmos, ... bioRxiv, 2023.09. 07.556691, 2023 | | 2023 |
Unfolded protein response IRE1/XBP1 signaling is required for healthy mammalian brain aging C Ibaceta-Gonzalez, CM Sabusap, F Bermedo-Garcia, P Mujica, ... The EMBO Journal, e111952, 2022 | | 2022 |