POINT technology illuminates the processing of polymerase-associated intact nascent transcripts R Sousa-Luis, G Dujardin, I Zukher, H Kimura, C Weldon, ... Molecular cell 81 (9), 1935-1950. e6, 2021 | 68 | 2021 |
Counteracting chromatin effects of a splicing-correcting antisense oligonucleotide improves its therapeutic efficacy in spinal muscular atrophy LE Marasco, G Dujardin, R Sousa-Luís, YH Liu, JN Stigliano, ... Cell 185 (12), 2057-2070. e15, 2022 | 51 | 2022 |
Transcriptome profiling of human pluripotent stem cell‐derived cerebellar organoids reveals faster commitment under dynamic conditions TP Silva, R Sousa‐Luís, TG Fernandes, EP Bekman, CAV Rodrigues, ... Biotechnology and Bioengineering 118 (7), 2781-2803, 2021 | 26 | 2021 |
Elongation roadblocks mediated by dCas9 across human genes modulate transcription and nascent RNA processing I Zukher, G Dujardin, R Sousa-Luís, NJ Proudfoot Nature Structural & Molecular Biology 30 (10), 1536-1548, 2023 | 6 | 2023 |
DNA-directed termination of mammalian RNA polymerase II L Davidson, JO Rouvière, R Sousa-Luís, T Nojima, NJ Proudfoot, ... Genes & Development, 2024 | 3 | 2024 |
Pseudouridylation: A new player in co-transcriptional splicing regulation R Sousa-Luís, M Carmo-Fonseca Molecular Cell 82 (3), 495-496, 2022 | 3 | 2022 |
Erosion of X-Chromosome Inactivation in female hiPSCs is heterogeneous and persists during differentiation AC Raposo, P Caldas, M Arez, J Jeremias, P Barbosa, R Sousa-Luis, ... bioRxiv, 2024.03. 15.585169, 2024 | | 2024 |