MicroRNA-directed transcriptional gene silencing in mammalian cells DH Kim, P Sætrom, O Snøve Jr, JJ Rossi Proceedings of the National Academy of Sciences 105 (42), 16230-16235, 2008 | 911 | 2008 |
An integrated expression atlas of miRNAs and their promoters in human and mouse D De Rie, I Abugessaisa, T Alam, E Arner, P Arner, H Ashoor, G Åström, ... Nature biotechnology 35 (9), 872-878, 2017 | 569 | 2017 |
MicroRNAs in disease and potential therapeutic applications HS Soifer, JJ Rossi, P Sætrom Molecular therapy 15 (12), 2070-2079, 2007 | 512 | 2007 |
Distance constraints between microRNA target sites dictate efficacy and cooperativity P Sætrom, BSE Heale, O Snøve Jr, L Aagaard, J Alluin, JJ Rossi Nucleic acids research 35 (7), 2333-2342, 2007 | 457 | 2007 |
Novel long noncoding RNAs are regulated by angiotensin II in vascular smooth muscle cells A Leung, C Trac, W Jin, L Lanting, A Akbany, P Sætrom, DE Schones, ... Circulation research 113 (3), 266-278, 2013 | 331 | 2013 |
Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol LA Lange, Y Hu, H Zhang, C Xue, EM Schmidt, ZZ Tang, C Bizon, ... The American Journal of Human Genetics 94 (2), 233-245, 2014 | 241 | 2014 |
Cell cycle regulation of human DNA repair and chromatin remodeling genes R Mjelle, SA Hegre, PA Aas, G Slupphaug, F Drabløs, P Sætrom, ... DNA repair 30, 53-67, 2015 | 232 | 2015 |
Circular RNAs are depleted of polymorphisms at microRNA binding sites LF Thomas, P Sætrom Bioinformatics 30 (16), 2243-2246, 2014 | 201 | 2014 |
Comparison of approaches for rational siRNA design leading to a new efficient and transparent method O Matveeva, Y Nechipurenko, L Rossi, B Moore, P Sætrom, AY Ogurtsov, ... Nucleic acids research 35 (8), e63, 2007 | 190 | 2007 |
Regulation of inflammatory phenotype in macrophages by a diabetes-induced long noncoding RNA MA Reddy, Z Chen, JT Park, M Wang, L Lanting, Q Zhang, K Bhatt, ... Diabetes 63 (12), 4249-4261, 2014 | 175 | 2014 |
MicroRNAs–targeting and target prediction T Saito, P Sætrom New biotechnology 27 (3), 243-249, 2010 | 173 | 2010 |
The importance of p53 pathway genetics in inherited and somatic cancer genomes G Stracquadanio, X Wang, MD Wallace, AM Grawenda, P Zhang, J Hewitt, ... Nature reviews Cancer 16 (4), 251-265, 2016 | 168 | 2016 |
A risk variant in an miR-125b binding site in BMPR1B is associated with breast cancer pathogenesis P Saetrom, J Biesinger, SM Li, D Smith, LF Thomas, K Majzoub, GE Rivas, ... Cancer research 69 (18), 7459-7465, 2009 | 168 | 2009 |
Weighted sequence motifs as an improved seeding step in microRNA target prediction algorithms OLA SaeTrom, O Snøve, P Sætrom Rna 11 (7), 995-1003, 2005 | 162 | 2005 |
A comparison of siRNA efficacy predictors P Sætrom, O Snøve Jr Biochemical and Biophysical Research Communications 321 (1), 247-253, 2004 | 150 | 2004 |
Engineering and optimization of the miR-106b cluster for ectopic expression of multiplexed anti-HIV RNAs LA Aagaard, J Zhang, KJ von Eije, H Li, P Sætrom, M Amarzguioui, ... Gene therapy 15 (23), 1536-1549, 2008 | 146 | 2008 |
Epigenetics and microRNAs P Saetrom, O Snøve, JJ Rossi Pediatric research 61 (7), 17-23, 2007 | 138 | 2007 |
Reliable prediction of Drosha processing sites improves microRNA gene prediction SA Helvik, O Snøve Jr, P Sætrom Bioinformatics 23 (2), 142-149, 2007 | 135 | 2007 |
Novel RNA oligonucleotide improves liver function and inhibits liver carcinogenesis in vivo V Reebye, P Sætrom, PJ Mintz, KW Huang, P Swiderski, L Peng, C Liu, ... Hepatology 59 (1), 216-227, 2014 | 131 | 2014 |
Predicting the efficacy of short oligonucleotides in antisense and RNAi experiments with boosted genetic programming P Sætrom Bioinformatics 20 (17), 3055-3063, 2004 | 109 | 2004 |