Discovery and characterization of ZUFSP/ZUP1, a distinct deubiquitinase class important for genome stability D Kwasna, SAA Rehman, J Natarajan, S Matthews, R Madden, ... Molecular Cell 70 (1), 150-164. e6, 2018 | 198 | 2018 |
VgrG and PAAR proteins define distinct versions of a functional type VI secretion system FR Cianfanelli, J Alcoforado Diniz, M Guo, V De Cesare, M Trost, ... PLoS pathogens 12 (6), e1005735, 2016 | 179 | 2016 |
Inhibition of USP10 induces degradation of oncogenic FLT3 EL Weisberg, NJ Schauer, J Yang, I Lamberto, L Doherty, S Bhatt, ... Nature chemical biology 13 (12), 1207-1215, 2017 | 114 | 2017 |
Deubiquitinating enzyme amino acid profiling reveals a class of ubiquitin esterases V De Cesare, D Carbajo Lopez, PD Mabbitt, AJ Fletcher, M Soetens, ... Proceedings of the National Academy of Sciences 118 (4), e2006947118, 2021 | 78 | 2021 |
The MALDI-TOF E2/E3 ligase assay as universal tool for drug discovery in the ubiquitin pathway V De Cesare, C Johnson, V Barlow, J Hastie, A Knebel, M Trost Cell chemical biology 25 (9), 1117-1127. e4, 2018 | 72 | 2018 |
Synthesis of isomeric phosphoubiquitin chains reveals that phosphorylation controls deubiquitinase activity and specificity N Huguenin-Dezot, V De Cesare, J Peltier, A Knebel, YA Kristaryianto, ... Cell reports 16 (4), 1180-1193, 2016 | 70 | 2016 |
Lithocholic acid hydroxyamide destabilizes cyclin D1 and induces G0/G1 arrest by inhibiting deubiquitinase USP2a K Magiera, M Tomala, K Kubica, V De Cesare, M Trost, BJ Zieba, ... Cell chemical biology 24 (4), 458-470. e18, 2017 | 52 | 2017 |
High-throughput matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry–based deubiquitylating enzyme assay for drug discovery V De Cesare, J Moran, R Traynor, A Knebel, MS Ritorto, M Trost, ... Nature Protocols 15 (12), 4034-4057, 2020 | 40 | 2020 |
Systematic reconstruction of the complete two-component sensorial network in Staphylococcus aureus B Rapun-Araiz, AF Haag, V De Cesare, C Gil, P Dorado-Morales, ... Msystems 5 (4), 10.1128/msystems. 00511-20, 2020 | 40 | 2020 |
The COP9 signalosome is involved in the regulation of lipid metabolism and of transition metals uptake in Saccharomyces cerevisiae V Licursi, C Salvi, V De Cesare, T Rinaldi, B Mattei, C Fabbri, G Serino, ... The FEBS journal 281 (1), 175-190, 2014 | 20 | 2014 |
Inhibiting multiple deubiquitinases to reduce androgen receptor expression in prostate cancer cells A de Las Pozas, T Reiner, V De Cesare, M Trost, C Perez-Stable Scientific reports 8 (1), 13146, 2018 | 15 | 2018 |
Comprehensive approach to study branched ubiquitin chains reveals roles for K48-K63 branches in VCP/p97-related processes SM Lange, MR McFarland, F Lamoliatte, D Kwaśna, L Shen, I Wallace, ... BioRxiv, 2023.01. 10.523363, 2023 | 11 | 2023 |
Characterization of protease activity of Nsp3 from SARS-CoV-2 and its in vitro inhibition by nanobodies LA Armstrong, SM Lange, V De Cesare, SP Matthews, RS Nirujogi, I Cole, ... BioRxiv, 2020.12. 09.417741, 2020 | 5 | 2020 |
High-throughput MALDI-TOF mass spectrometry-based deubiquitylating enzyme assay for drug discovery V De Cesare, P Davies Deubiquitinases: Methods and Protocols, 123-134, 2022 | 4 | 2022 |
Discovery and characterization of noncanonical E2-conjugating enzymes SA Abdul Rehman, C Cazzaniga, E Di Nisio, O Antico, A Knebel, ... Science Advances 10 (13), eadh0123, 2024 | 3 | 2024 |
Elaboration of a MALDI-TOF mass spectrometry-based assay of parkin activity and high-throughput screening platform for parkin activators R Traynor, J Moran, M Stevens, A Knebel, B Behrouz, K Merchant, ... bioRxiv, 2022.03. 04.482851, 2022 | 2 | 2022 |
Role of the COP9 signalosome in transcription modulation of genes involved in lipid metabolism and ergosterol biosynthesis in S. cerevisiae V DE CESARE, V Di Maria, C Salvi, V Licursi, T Rinaldi, G Serino, ... THE FEBS JOURNAL 278 (1), 83-83, 2011 | 2 | 2011 |
Design and high-throughput implementation of MALDI-TOF/MS-based assays for Parkin E3 ligase activity R Traynor, J Moran, M Stevens, O Antico, A Knebel, B Behrouz, ... Cell Reports Methods 4 (2), 2024 | 1 | 2024 |
MALDI-TOF Mass Spectrometry for interrogating ubiquitin enzymes V De Cesare Frontiers in Molecular Biosciences 10, 1184934, 2023 | 1 | 2023 |
VCP/p97-associated proteins are binders and debranching enzymes of K48–K63-branched ubiquitin chains SM Lange, MR McFarland, F Lamoliatte, T Carroll, L Krshnan, ... Nature Structural & Molecular Biology, 1-16, 2024 | | 2024 |