The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA IC Allen, MA Scull, CB Moore, EK Holl, E McElvania-TeKippe, DJ Taxman, ... Immunity 30 (4), 556-565, 2009 | 1307 | 2009 |
The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer IC Allen, EME TeKippe, RMT Woodford, JM Uronis, EK Holl, AB Rogers, ... Journal of Experimental Medicine 207 (5), 1045-1056, 2010 | 886 | 2010 |
Natural, incidental, and engineered nanomaterials and their impacts on the Earth system MF Hochella Jr, DW Mogk, J Ranville, IC Allen, GW Luther, LC Marr, ... Science 363 (6434), eaau8299, 2019 | 632 | 2019 |
NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling IC Allen, JE Wilson, M Schneider, JD Lich, RA Roberts, JC Arthur, ... Immunity 36 (5), 742-754, 2012 | 549 | 2012 |
Staphylococcus aureus α-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells RR Craven, X Gao, IC Allen, D Gris, JB Wardenburg, ... PloS one 4 (10), e7446, 2009 | 503 | 2009 |
NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways IC Allen, CB Moore, M Schneider, Y Lei, BK Davis, MA Scull, D Gris, ... Immunity 34 (6), 854-865, 2011 | 404 | 2011 |
NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and-independent pathways SB Willingham, IC Allen, DT Bergstralh, WJ Brickey, MTH Huang, ... The Journal of Immunology 183 (3), 2008-2015, 2009 | 393 | 2009 |
The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB M Schneider, AG Zimmermann, RA Roberts, L Zhang, KV Swanson, ... Nature immunology 13 (9), 823-831, 2012 | 334 | 2012 |
Staphylococcus aureus α-Hemolysin Mediates Virulence in a Murine Model of Severe Pneumonia Through Activation of the NLRP3 Inflammasome C Kebaier, RR Chamberland, IC Allen, X Gao, PM Broglie, JD Hall, ... Journal of Infectious Diseases 205 (5), 807-817, 2012 | 290 | 2012 |
TLR2/MyD88/NF-κB pathway, reactive oxygen species, potassium efflux activates NLRP3/ASC inflammasome during respiratory syncytial virus infection J Segovia, A Sabbah, V Mgbemena, SY Tsai, TH Chang, MT Berton, ... PloS one 7 (1), e29695, 2012 | 282 | 2012 |
Granuloma Formation and Host Defense in Chronic Mycobacterium tuberculosis Infection Requires PYCARD/ASC but Not NLRP3 or Caspase-1 E McElvania TeKippe, IC Allen, PD Hulseberg, JT Sullivan, JR McCann, ... PloS one 5 (8), e12320, 2010 | 195 | 2010 |
High-frequency irreversible electroporation is an effective tumor ablation strategy that induces immunologic cell death and promotes systemic anti-tumor immunity VM Ringel-Scaia, N Beitel-White, MF Lorenzo, RM Brock, KE Huie, ... EBioMedicine 44, 112-125, 2019 | 174 | 2019 |
The inflammasome component NLRP3 impairs antitumor vaccine by enhancing the accumulation of tumor-associated myeloid-derived suppressor cells HW Van Deventer, JE Burgents, QP Wu, RMT Woodford, WJ Brickey, ... Cancer research 70 (24), 10161-10169, 2010 | 166 | 2010 |
Cutting edge: NLRP12 controls dendritic and myeloid cell migration to affect contact hypersensitivity JC Arthur, JD Lich, Z Ye, IC Allen, D Gris, JE Wilson, M Schneider, ... The Journal of Immunology 185 (8), 4515-4519, 2010 | 165 | 2010 |
Emerging roles for noncanonical NF-κB signaling in the modulation of inflammatory bowel disease pathobiology DK McDaniel, K Eden, VM Ringel, IC Allen Inflammatory bowel diseases 22 (9), 2265-2279, 2016 | 156 | 2016 |
The NLRP1 inflammasome attenuates colitis and colitis-associated tumorigenesis TM Williams, RA Leeth, DE Rothschild, SL Coutermarsh-Ott, DK McDaniel, ... The Journal of Immunology 194 (7), 3369-3380, 2015 | 156 | 2015 |
Nanoscale bacteria‐enabled autonomous drug delivery system (NanoBEADS) enhances intratumoral transport of nanomedicine SB Suh, A Jo, MA Traore, Y Zhan, SL Coutermarsh‐Ott, VM Ringel‐Scaia, ... Advanced Science 6 (3), 1801309, 2019 | 140 | 2019 |
The pro-inflammatory chemokines CXCL9, CXCL10 and CXCL11 are upregulated following SARS-CoV-2 infection in an AKT-dependent manner V Callahan, S Hawks, MA Crawford, CW Lehman, HA Morrison, ... Viruses 13 (6), 1062, 2021 | 118 | 2021 |
Photo-triggered release of 5-fluorouracil from a MOF drug delivery vehicle KR Stefaniak, CC Epley, JJ Novak, ML McAndrew, HD Cornell, J Zhu, ... Chemical Communications 54 (55), 7617-7620, 2018 | 114 | 2018 |
Beyond the inflammasome: regulatory NOD-like receptor modulation of the host immune response following virus exposure S Coutermarsh-Ott, K Eden, IC Allen Journal of General Virology 97 (4), 825-838, 2016 | 114 | 2016 |