| The structural modification of natural products for novel drug discovery H Yao, J Liu, S Xu, Z Zhu, J Xu Expert opinion on drug discovery 12 (2), 121-140, 2017 | 250 | 2017 |
| Multi-target design strategies for the improved treatment of Alzheimer's disease P Zhang, S Xu, Z Zhu, J Xu European journal of medicinal chemistry 176, 228-247, 2019 | 207 | 2019 |
| Tubulin inhibitors targeting the colchicine binding site: a perspective of privileged structures W Li, H Sun, S Xu, Z Zhu, J Xu Future medicinal chemistry 9 (15), 1765-1794, 2017 | 141 | 2017 |
| Discovery of novel quinoline–chalcone derivatives as potent antitumor agents with microtubule polymerization inhibitory activity W Li, F Xu, W Shuai, H Sun, H Yao, C Ma, S Xu, H Yao, Z Zhu, DH Yang, ... Journal of medicinal chemistry 62 (2), 993-1013, 2018 | 123 | 2018 |
| Elucidation of xenobiotic metabolism pathways in human skin and human skin models by proteomic profiling S van Eijl, Z Zhu, J Cupitt, M Gierula, C Götz, E Fritsche, RJ Edwards PloS one 7 (7), e41721, 2012 | 103 | 2012 |
| Gastroretentive technologies in tandem with controlled-release strategies: A potent answer to oral drug bioavailability and patient compliance implications NN Vrettos, CJ Roberts, Z Zhu Pharmaceutics 13 (10), 1591, 2021 | 84 | 2021 |
| Small molecules as inhibitors of PCSK9: Current status and future challenges S Xu, S Luo, Z Zhu, J Xu European journal of medicinal chemistry 162, 212-233, 2019 | 74 | 2019 |
| Design, synthesis and biological evaluation of quinoline-indole derivatives as anti-tubulin agents targeting the colchicine binding site W Li, W Shuai, H Sun, F Xu, Y Bi, J Xu, C Ma, H Yao, Z Zhu, S Xu European Journal of Medicinal Chemistry 163, 428-442, 2019 | 73 | 2019 |
| Design, synthesis and biological evaluation of pyridine-chalcone derivatives as novel microtubule-destabilizing agents F Xu, W Li, W Shuai, L Yang, Y Bi, C Ma, H Yao, S Xu, Z Zhu, J Xu European journal of medicinal chemistry 173, 1-14, 2019 | 60 | 2019 |
| New insights into neuroinflammation involved in pathogenic mechanism of Alzheimer’s disease and its potential for therapeutic intervention T Li, L Lu, E Pember, X Li, B Zhang, Z Zhu Cells 11 (12), 1925, 2022 | 59 | 2022 |
| Discovery of novel tacrine–pyrimidone hybrids as potent dual AChE/GSK-3 inhibitors for the treatment of Alzheimer’s disease H Yao, G Uras, P Zhang, S Xu, Y Yin, J Liu, S Qin, X Li, S Allen, R Bai, ... Journal of Medicinal Chemistry 64 (11), 7483-7506, 2021 | 55 | 2021 |
| Expression of P450 enzymes in rat whole skin and cultured epidermal keratinocytes Z Zhu, SA Hotchkiss, AR Boobis, RJ Edwards Biochemical and biophysical research communications 297 (1), 65-70, 2002 | 45 | 2002 |
| Discovery of norbornene as a novel hydrophobic tag applied in protein degradation S Xie, F Zhan, J Zhu, Y Sun, H Zhu, J Liu, J Chen, Z Zhu, DH Yang, ... Angewandte Chemie 135 (13), e202217246, 2023 | 44 | 2023 |
| Discovery of novel antitumor nitric oxide-donating β-elemene hybrids through inhibiting the PI3K/Akt pathway J Chen, T Wang, S Xu, P Zhang, A Lin, L Wu, H Yao, W Xie, Z Zhu, J Xu European Journal of Medicinal Chemistry 135, 414-423, 2017 | 44 | 2017 |
| Design, synthesis, and biological evaluation of NAD (P) H: Quinone oxidoreductase (NQO1)-targeted oridonin prodrugs possessing indolequinone moiety for hypoxia-selective activation S Xu, H Yao, L Pei, M Hu, D Li, Y Qiu, G Wang, L Wu, H Yao, Z Zhu, J Xu European journal of medicinal chemistry 132, 310-321, 2017 | 44 | 2017 |
| Mineral metabolism and ferroptosis in non-alcoholic fatty liver diseases C Ma, L Han, Z Zhu, CH Pang, G Pan Biochemical Pharmacology 205, 115242, 2022 | 43 | 2022 |
| Discovery of novel quinazolines as potential anti-tubulin agents occupying three zones of colchicine domain W Li, Y Yin, W Shuai, F Xu, H Yao, J Liu, K Cheng, J Xu, Z Zhu, S Xu Bioorganic chemistry 83, 380-390, 2019 | 40 | 2019 |
| Design, synthesis and biological evaluation of novel nitric oxide-donating protoberberine derivatives as antitumor agents J Chen, T Wang, S Xu, A Lin, H Yao, W Xie, Z Zhu, J Xu European journal of medicinal chemistry 132, 173-183, 2017 | 40 | 2017 |
| Increased expression of histone proteins during estrogen-mediated cell proliferation Z Zhu, RJ Edwards, AR Boobis Environmental health perspectives 117 (6), 928-934, 2009 | 39 | 2009 |
| Discovery of novel vinyl sulfone derivatives as anti-tumor agents with microtubule polymerization inhibitory and vascular disrupting activities W Li, Y Yin, H Yao, W Shuai, H Sun, S Xu, J Liu, H Yao, Z Zhu, J Xu European Journal of Medicinal Chemistry 157, 1068-1080, 2018 | 37 | 2018 |
