关注
Connor Arkinson
Connor Arkinson
未知所在单位机构
在 berkeley.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Parkin function in Parkinson's disease
C Arkinson, H Walden
Science 360 (6386), 267-268, 2018
812018
Differential functions of FANCI and FANCD2 ubiquitination stabilize ID2 complex on DNA
ML Rennie, K Lemonidis, C Arkinson, VK Chaugule, M Clarke, J Streetley, ...
EMBO reports 21 (7), e50133, 2020
372020
Structural basis of FANCD2 deubiquitination by USP1− UAF1
ML Rennie, C Arkinson, VK Chaugule, R Toth, H Walden
Nature Structural & Molecular Biology 28 (4), 356-364, 2021
352021
Allosteric targeting of the Fanconi anemia ubiquitin-conjugating enzyme Ube2T by fragment screening
FE Morreale, A Bortoluzzi, VK Chaugule, C Arkinson, H Walden, A Ciulli
Journal of medicinal chemistry 60 (9), 4093-4098, 2017
352017
Mechanism, specificity, and function of FANCD2‐FANCI ubiquitination and deubiquitination
K Lemonidis, C Arkinson, ML Rennie, H Walden
The FEBS Journal 289 (16), 4811-4829, 2022
312022
Allosteric mechanism for site-specific ubiquitination of FANCD2
VK Chaugule, C Arkinson, ML Rennie, O Kämäräinen, R Toth, H Walden
Nature chemical biology 16 (3), 291-301, 2020
252020
Specificity for deubiquitination of monoubiquitinated FANCD2 is driven by the N-terminus of USP1
C Arkinson, VK Chaugule, R Toth, H Walden
Life Science Alliance 1 (5), 2018
222018
The Ufd1 cofactor determines the linkage specificity of polyubiquitin chain engagement by the AAA+ ATPase Cdc48
C Williams, KC Dong, C Arkinson, A Martin
Molecular cell 83 (5), 759-769. e7, 2023
172023
Enzymatic preparation of monoubiquitinated FANCD2 and FANCI proteins
VK Chaugule, C Arkinson, R Toth, H Walden
Methods in Enzymology 618, 73-104, 2019
142019
Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site
ML Rennie, C Arkinson, VK Chaugule, H Walden
Science Advances 8 (39), eabq6353, 2022
112022
Structural and biochemical basis of interdependent FANCI‐FANCD2 ubiquitination
K Lemonidis, ML Rennie, C Arkinson, VK Chaugule, M Clarke, J Streetley, ...
The EMBO Journal 42 (3), e111898, 2023
82023
Allosteric network in Ube2T drives specificity for RING E3 catalysed ubiquitin signals
VK Chaugule, C Arkinson, R Toth, H Walden
bioRxiv, 429076, 2018
32018
Profiling ubiquitin signalling with UBIMAX reveals DNA damage- and SCFβ-Trcp1-dependent ubiquitylation of the actin-organizing protein Dbn1
CS Colding-Christensen, ES Kakulidis, J Arroyo-Gomez, IA Hendriks, ...
Nature Communications 14 (1), 8293, 2023
22023
Structural and Biochemical Insights into the Mechanism of Action of the Clinical USP1 Inhibitor, KSQ-4279
ML Rennie, M Gundogdu, C Arkinson, S Liness, S Frame, H Walden
Journal of Medicinal Chemistry, 2024
2024
Cryo-EM structure of the CDK2-cyclin A-CDC25A complex
RJ Rowland, S Korolchuk, M Salamina, NJ Tatum, JR Ault, S Hart, ...
Nature Communications, 2024
2024
Nub1 traps unfolded FAT10 for ubiquitin-independent degradation by the 26S proteasome
C Arkinson, KC Dong, CL Gee, SM Costello, S Marqusee, A Martin
bioRxiv, 2024.06. 12.598715, 2024
2024
Preparation of site-specifically fluorophore-labeled polyubiquitin chains for FRET studies of Cdc48 substrate processing
C Williams, KC Dong, C Arkinson, A Martin
STAR protocols 4 (4), 102659, 2023
2023
Structural and biochemical basis of FANCI-FANCD2 interdependent ubiquitination
K Lemonidis, ML Rennie, C Arkinson, VK Chaugule, M Clarke, J Streetley, ...
bioRxiv, 2022.04. 07.487446, 2022
2022
Regulation and substrate specificity of the USP1-UAF1 deubiquitinase complex
C Arkinson
University of Glasgow, 2020
2020
Validation Report Service
P Leone, C Bebeacua, O Opota, C Kellenberger, B Klaholz, C Cambillau, ...
系统目前无法执行此操作,请稍后再试。
文章 1–20