COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options TJ Guzik, SA Mohiddin, A Dimarco, V Patel, K Savvatis, FM Marelli-Berg, ... Cardiovascular research 116 (10), 1666-1687, 2020 | 1643 | 2020 |
Hypertrophic cardiomyopathy: genetics, pathogenesis, clinical manifestations, diagnosis, and therapy AJ Marian, E Braunwald Circulation research 121 (7), 749-770, 2017 | 1191 | 2017 |
Identification of a genetic locus for familial atrial fibrillation R Brugada, T Tapscott, GZ Czernuszewicz, AJ Marian, A Iglesias, L Mont, ... New England Journal of Medicine 336 (13), 905-911, 1997 | 820 | 1997 |
Tissue Doppler imaging consistently detects myocardial abnormalities in patients with hypertrophic cardiomyopathy and provides a novel means for an early diagnosis before and … SF Nagueh, LL Bachinski, D Meyer, R Hill, WA Zoghbi, JW Tam, ... Circulation 104 (2), 128-130, 2001 | 769 | 2001 |
Suppression of canonical Wnt/β-catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular cardiomyopathy E Garcia-Gras, R Lombardi, MJ Giocondo, JT Willerson, MD Schneider, ... The Journal of clinical investigation 116 (7), 2012-2021, 2006 | 723 | 2006 |
Mavacamten for treatment of symptomatic obstructive hypertrophic cardiomyopathy (EXPLORER-HCM): a randomised, double-blind, placebo-controlled, phase 3 trial I Olivotto, A Oreziak, R Barriales-Villa, TP Abraham, A Masri, ... The Lancet 396 (10253), 759-769, 2020 | 699 | 2020 |
The molecular genetic basis for hypertrophic cardiomyopathy AJ Marian, R Roberts Journal of molecular and cellular cardiology 33 (4), 655-670, 2001 | 664 | 2001 |
Mutations in smooth muscle alpha-actin (ACTA2) cause coronary artery disease, stroke, and Moyamoya disease, along with thoracic aortic disease DC Guo, CL Papke, V Tran-Fadulu, ES Regalado, N Avidan, RJ Johnson, ... The American Journal of Human Genetics 84 (5), 617-627, 2009 | 604 | 2009 |
Angiotensin-converting enzyme polymorphism in hypertrophic cardiomyopathy and sudden cardiac death AJ Marian, QT Yu, R Workman, G Greve, R Roberts The Lancet 342 (8879), 1085-1086, 1993 | 509 | 1993 |
Simvastatin induces regression of cardiac hypertrophy and fibrosis and improves cardiac function in a transgenic rabbit model of human hypertrophic cardiomyopathy R Patel, SF Nagueh, N Tsybouleva, M Abdellatif, S Lutucuta, HA Kopelen, ... Circulation 104 (3), 317-324, 2001 | 502 | 2001 |
A variant of human paraoxonase/arylesterase (HUMPONA) gene is a risk factor for coronary artery disease. M Serrato, AJ Marian The Journal of clinical investigation 96 (6), 3005-3008, 1995 | 477 | 1995 |
Angiotensin II blockade reverses myocardial fibrosis in a transgenic mouse model of human hypertrophic cardiomyopathy DS Lim, S Lutucuta, P Bachireddy, K Youker, A Evans, M Entman, ... Circulation 103 (6), 789-791, 2001 | 474 | 2001 |
Pathogenesis of diverse clinical and pathological phenotypes in hypertrophic cardiomyopathy AJ Marian The Lancet 355 (9197), 58-60, 2000 | 355 | 2000 |
Recent advances in the molecular genetics of hypertrophic cardiomyopathy AJ Marian, R Roberts Circulation 92 (5), 1336-1347, 1995 | 328 | 1995 |
Tissue Doppler imaging predicts the development of hypertrophic cardiomyopathy in subjects with subclinical disease SF Nagueh, J McFalls, D Meyer, R Hill, WA Zoghbi, JW Tam, ... Circulation 108 (4), 395-398, 2003 | 320 | 2003 |
MYH11 mutations result in a distinct vascular pathology driven by insulin-like growth factor 1 and angiotensin II H Pannu, V Tran-Fadulu, CL Papke, S Scherer, Y Liu, C Presley, D Guo, ... Human molecular genetics 16 (20), 2453-2462, 2007 | 318 | 2007 |
Angiotensin-I converting enzyme genotypes and left ventricular hypertrophy in patients with hypertrophic cardiomyopathy M Lechin, MA Quiñones, A Omran, R Hill, QT Yu, H Rakowski, D Wigle, ... Circulation 92 (7), 1808-1812, 1995 | 308 | 1995 |
Endothelial lipase is a major genetic determinant for high-density lipoprotein concentration, structure, and metabolism K Ma, M Cilingiroglu, JD Otvos, CM Ballantyne, AJ Marian, L Chan Proceedings of the National Academy of Sciences 100 (5), 2748-2753, 2003 | 299 | 2003 |
Aldosterone, through novel signaling proteins, is a fundamental molecular bridge between the genetic defect and the cardiac phenotype of hypertrophic cardiomyopathy N Tsybouleva, L Zhang, S Chen, R Patel, S Lutucuta, S Nemoto, ... Circulation 109 (10), 1284-1291, 2004 | 294 | 2004 |
The hippo pathway is activated and is a causal mechanism for adipogenesis in arrhythmogenic cardiomyopathy SN Chen, P Gurha, R Lombardi, A Ruggiero, JT Willerson, AJ Marian Circulation research 114 (3), 454-468, 2014 | 285 | 2014 |