H19 induces abdominal aortic aneurysm development and progression DY Li, A Busch, H Jin, E Chernogubova, J Pelisek, J Karlsson, ... Circulation 138 (15), 1551-1568, 2018 | 212 | 2018 |
Molecular profiling of driver events in metastatic uveal melanoma J Karlsson, LM Nilsson, S Mitra, S Alsén, GV Shelke, VR Sah, ... Nature communications 11 (1), 1894, 2020 | 126 | 2020 |
The PEMDAC phase 2 study of pembrolizumab and entinostat in patients with metastatic uveal melanoma L Ny, H Jespersen, J Karlsson, S Alsén, S Filges, C All-Eriksson, ... Nature communications 12 (1), 5155, 2021 | 119 | 2021 |
Global analysis of somatic structural genomic alterations and their impact on gene expression in diverse human cancers B Alaei-Mahabadi, J Bhadury, JW Karlsson, JA Nilsson, E Larsson Proceedings of the National Academy of Sciences 113 (48), 13768-13773, 2016 | 71 | 2016 |
Patient-derived scaffolds uncover breast cancer promoting properties of the microenvironment G Landberg, P Fitzpatrick, P Isakson, E Jonasson, J Karlsson, E Larsson, ... Biomaterials 235, 119705, 2020 | 53 | 2020 |
Targeting filamin A reduces macrophage activity and atherosclerosis S Bandaru, C Ala, R Salimi, MK Akula, M Ekstrand, S Devarakonda, ... Circulation 140 (1), 67-79, 2019 | 50 | 2019 |
Supporting clinical decision making in advanced melanoma by preclinical testing in personalized immune-humanized xenograft mouse models L Ny, LY Rizzo, V Belgrano, J Karlsson, H Jespersen, L Carstam, ... Annals of Oncology 31 (2), 266-273, 2020 | 43 | 2020 |
A patient-derived xenograft pre-clinical trial reveals treatment responses and a resistance mechanism to karonudib in metastatic melanoma BO Einarsdottir, J Karlsson, EMV Söderberg, MF Lindberg, ... Cell Death & Disease 9 (8), 810, 2018 | 41 | 2018 |
Identification of breast cancer stem cell related genes using functional cellular assays combined with single-cell RNA sequencing in MDA-MB-231 cells E Jonasson, S Ghannoum, E Persson, J Karlsson, T Kroneis, E Larsson, ... Frontiers in genetics 10, 500, 2019 | 36 | 2019 |
The MTH1 inhibitor TH588 is a microtubule-modulating agent that eliminates cancer cells by activating the mitotic surveillance pathway N Gul, J Karlsson, C Tängemo, S Linsefors, S Tuyizere, R Perkins, C Ala, ... Scientific reports 9 (1), 14667, 2019 | 23 | 2019 |
Intussusceptive angiogenesis in human metastatic malignant melanoma A Pandita, M Ekstrand, S Bjursten, Z Zhao, P Fogelstrand, K Le Gal, L Ny, ... The American Journal of Pathology 191 (11), 2023-2038, 2021 | 21 | 2021 |
Transcriptomic characterization of the human cell cycle in individual unsynchronized cells J Karlsson, T Kroneis, E Jonasson, E Larsson, A Ståhlberg Journal of molecular biology 429 (24), 3909-3924, 2017 | 19 | 2017 |
Treatment with anti-HER2 chimeric antigen receptor tumor-infiltrating lymphocytes (CAR-TILs) is safe and associated with antitumor efficacy in mice and companion dogs EMV Forsberg, R Riise, S Saellström, J Karlsson, S Alsén, V Bucher, ... Cancers 15 (3), 648, 2023 | 16 | 2023 |
Epigenetic therapy to enhance therapeutic effects of PD-1 inhibition in therapy-resistant melanoma VR Sah, J Karlsson, H Jespersen, MF Lindberg, LM Nilsson, L Ny, ... Melanoma Research 32 (4), 241-248, 2022 | 15 | 2022 |
SARS-CoV-2 replicates and displays oncolytic properties in clear cell and papillary renal cell carcinoma OK Choong, R Jakobsson, AG Bergdahl, S Brunet, A Kärmander, ... PLoS One 18 (1), e0279578, 2023 | 12 | 2023 |
Mutational signature and transcriptomic classification analyses as the decisive diagnostic tools for a cancer of unknown primary RO Bagge, A Demir, J Karlsson, B Alaei-Mahabadi, BO Einarsdottir, ... JCO precision oncology 2, 1-25, 2018 | 11 | 2018 |
Characterization of cell-free breast cancer patient-derived scaffolds using liquid chromatography-mass spectrometry/mass spectrometry data and RNA sequencing data G Landberg, E Jonasson, A Gustafsson, P Fitzpatrick, P Isakson, ... Data in Brief 31, 105860, 2020 | 10 | 2020 |
The microenvironment of small intestinal neuroendocrine tumours contains lymphocytes capable of recognition and activation after expansion T Hofving, F Liang, J Karlsson, U Yrlid, JA Nilsson, O Nilsson, LM Nilsson Cancers 13 (17), 4305, 2021 | 7 | 2021 |
FocalScan: Scanning for altered genes in cancer based on coordinated DNA and RNA change J Karlsson, E Larsson Nucleic acids research 44 (19), e150-e150, 2016 | 5 | 2016 |
H-STS, L-STS and KRJ-I are not authentic GEPNET cell lines T Hofving, J Karlsson, O Nilsson, JA Nilsson Nature Genetics 51 (10), 1426-1427, 2019 | 4 | 2019 |