MYC promotes tryptophan uptake and metabolism by the kynurenine pathway in colon cancer N Venkateswaran, MC Lafita-Navarro, YH Hao, JA Kilgore, ... Genes & development 33 (17-18), 1236-1251, 2019 | 160 | 2019 |
Induction of LEF1 by MYC activates the WNT pathway and maintains cell proliferation YH Hao, MC Lafita-Navarro, L Zacharias, N Borenstein-Auerbach, M Kim, ... Cell Communication and Signaling 17, 1-16, 2019 | 71 | 2019 |
Nucleolar stress: From development to cancer MC Lafita-Navarro, M Conacci-Sorrell Seminars in cell & developmental biology 136, 64-74, 2023 | 56 | 2023 |
p21 as a transcriptional co-repressor of S-phase and mitotic control genes N Ferrándiz, JM Caraballo, L Garcia-Gutierrez, V Devgan, ... PLoS One 7 (5), e37759, 2012 | 52 | 2012 |
ODZ1 allows glioblastoma to sustain invasiveness through a Myc-dependent transcriptional upregulation of RhoA A Talamillo, L Grande, P Ruiz-Ontañon, C Velásquez, P Mollinedo, ... Oncogene 36 (12), 1733-1744, 2017 | 47 | 2017 |
Inhibition of the de novo pyrimidine biosynthesis pathway limits ribosomal RNA transcription causing nucleolar stress in glioblastoma cells MC Lafita-Navarro, N Venkateswaran, JA Kilgore, S Kanji, J Han, ... PLoS genetics 16 (11), e1009117, 2020 | 46 | 2020 |
Sin3b interacts with Myc and decreases Myc levels P Garcia-Sanz, A Quintanilla, MC Lafita, G Moreno-Bueno, ... Journal of Biological Chemistry 289 (32), 22221-22236, 2014 | 42 | 2014 |
The aryl hydrocarbon receptor regulates nucleolar activity and protein synthesis in MYC-expressing cells MC Lafita-Navarro, M Kim, N Borenstein-Auerbach, N Venkateswaran, ... Genes & development 32 (19-20), 1303-1308, 2018 | 38 | 2018 |
MXD1 localizes in the nucleolus, binds UBF and impairs rRNA synthesis M del Carmen Lafita-Navarro, R Blanco, J Mata-Garrido, J Liaño-Pons, ... Oncotarget 7 (43), 69536, 2016 | 30 | 2016 |
The transcription factors aryl hydrocarbon receptor and MYC cooperate in the regulation of cellular metabolism MC Lafita-Navarro, L Perez-Castro, LG Zacharias, S Barnes, ... Journal of Biological Chemistry 295 (35), 12398-12407, 2020 | 24 | 2020 |
The MNT transcription factor autoregulates its expression and supports proliferation in MYC-associated factor X (MAX)-deficient cells MC Lafita-Navarro, J Liaño-Pons, A Quintanilla, I Varela, R Blanco, ... Journal of Biological Chemistry 295 (7), 2001-2017, 2020 | 14 | 2020 |
Regulation of nucleolar activity by MYC IN Brown, MC Lafita-Navarro, M Conacci-Sorrell Cells 11 (3), 574, 2022 | 13 | 2022 |
The AHR target gene scinderin activates the WNT pathway by facilitating the nuclear translocation of β-catenin L Perez-Castro, N Venkateswaran, R Garcia, YH Hao, MC Lafita-Navarro, ... Journal of cell science 135 (20), jcs260028, 2022 | 8 | 2022 |
NUMB inactivation confers resistance to imatinib in chronic myeloid leukemia cells E García-Alegría, MC Lafita-Navarro, R Aguado, L Garcia-Gutierrez, ... Cancer Letters 375 (1), 92-99, 2016 | 8 | 2016 |
Tryptophan fuels MYC-dependent liver tumorigenesis through indole 3-pyruvate synthesis N Venkateswaran, R Garcia, MC Lafita-Navarro, YH Hao, L Perez-Castro, ... Nature communications 15 (1), 4266, 2024 | 1 | 2024 |
ZNF692 organizes a hub specialized in 40S ribosomal subunit maturation enhancing translation in rapidly proliferating cells MC Lafita-Navarro, YH Hao, C Jiang, S Jang, TC Chang, IN Brown, ... Cell reports 42 (10), 2023 | 1 | 2023 |
A novel role of MNT as a negative regulator of REL and the NF-κB pathway J Liaño-Pons, MC Lafita-Navarro, L García-Gaipo, C Colomer, ... Oncogenesis 10 (1), 5, 2021 | 1 | 2021 |
MYC-Mediated Inhibition of ARNT2 Uncovers a Key Tumor Suppressor in Glioblastoma M Conacci-Sorrell, YH Hao, N Borenstein-Auerbach, A Grichuk, L Li, ... | | 2024 |
Targeting of neuroblastoma cells through Kynurenine‐AHR pathway inhibition IL Dos Santos, M Mitchell, PAS Nogueira, MC Lafita‐Navarro, ... The FEBS Journal 291 (10), 2172-2190, 2024 | | 2024 |
ZNF692 regulates nucleolar morphology by interacting with NPM1 and modifying its self-assembly properties IN Brown, A Levario, C Jiang, W Stachera, E Rodriguez, YH Hao, ... Journal of Biological Chemistry 300 (3), 2024 | | 2024 |