Adipose-derived circulating miRNAs regulate gene expression in other tissues T Thomou, MA Mori, JM Dreyfuss, M Konishi, M Sakaguchi, C Wolfrum, ... Nature 542 (7642), 450-455, 2017 | 1390 | 2017 |
Insulin regulates astrocyte gliotransmission and modulates behavior W Cai, C Xue, M Sakaguchi, M Konishi, A Shirazian, HA Ferris, ME Li, ... The Journal of clinical investigation 128 (7), 2914-2926, 2018 | 198 | 2018 |
Insulin signaling in the hippocampus and amygdala regulates metabolism and neurobehavior M Soto, W Cai, M Konishi, CR Kahn Proceedings of the National Academy of Sciences 116 (13), 6379-6384, 2019 | 189 | 2019 |
Antibiotic effects on gut microbiota and metabolism are host dependent S Fujisaka, S Ussar, C Clish, S Devkota, JM Dreyfuss, M Sakaguchi, ... The Journal of clinical investigation 126 (12), 4430-4443, 2016 | 168 | 2016 |
Adipocyte dynamics and reversible metabolic syndrome in mice with an inducible adipocyte-specific deletion of the insulin receptor M Sakaguchi, S Fujisaka, W Cai, JN Winnay, M Konishi, BT O'Neill, M Li, ... Cell Metabolism 25 (2), 448-462, 2017 | 128 | 2017 |
Endothelial insulin receptors differentially control insulin signaling kinetics in peripheral tissues and brain of mice M Konishi, M Sakaguchi, SM Lockhart, W Cai, ME Li, EP Homan, ... Proceedings of the National Academy of Sciences 114 (40), E8478-E8487, 2017 | 127 | 2017 |
Fos activation in hypothalamic neurons during cold or warm exposure: projections to periaqueductal gray matter K Yoshida, M Konishi, K Nagashima, CB Saper, K Kanosue Neuroscience 133 (4), 1039-1046, 2005 | 99 | 2005 |
Effects of fasting on thermoregulatory processes and the daily oscillations in rats K Nagashima, S Nakai, K Matsue, M Konishi, M Tanaka, K Kanosue American Journal of Physiology-Regulatory, Integrative and Comparative …, 2003 | 71 | 2003 |
Multi-dimensional transcriptional remodeling by physiological insulin in vivo TM Batista, R Garcia-Martin, W Cai, M Konishi, BT O’Neill, M Sakaguchi, ... Cell reports 26 (12), 3429-3443. e3, 2019 | 70 | 2019 |
The involvement of Cry1 and Cry2 genes in the regulation of the circadian body temperature rhythm in mice K Nagashima, K Matsue, M Konishi, C Iidaka, K Miyazaki, N Ishida, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2005 | 49 | 2005 |
Brain regions expressing Fos during thermoregulatory behavior in rats M Maruyama, M Nishi, M Konishi, Y Takashige, K Nagashima, T Kiyohara, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2003 | 40 | 2003 |
Synthesis and evaluation of novel stearoyl-CoA desaturase 1 inhibitors: 1′-{6-[5-(pyridin-3-ylmethyl)-1, 3, 4-oxadiazol-2-yl] pyridazin-3-yl}-3, 4-dihydrospiro [chromene-2, 4 … Y Uto, Y Ueno, Y Kiyotsuka, Y Miyazawa, H Kurata, T Ogata, M Yamada, ... European journal of medicinal chemistry 45 (11), 4788-4796, 2010 | 38 | 2010 |
Novel and potent inhibitors of stearoyl-CoA desaturase-1. Part II: Identification of 4-ethylamino-3-(2-hydroxyethoxy)-N-[5-(3-trifluoromethylbenzyl) thiazol-2-yl] benzamide and … Y Uto, T Ogata, Y Kiyotsuka, Y Miyazawa, Y Ueno, H Kurata, T Deguchi, ... Bioorganic & medicinal chemistry letters 19 (15), 4159-4166, 2009 | 36 | 2009 |
Novel spiropiperidine-based stearoyl-CoA desaturase-1 inhibitors: Identification of 1′-{6-[5-(pyridin-3-ylmethyl)-1, 3, 4-oxadiazol-2-yl] pyridazin-3-yl}-5-(trifluoromethyl)-3 … Y Uto, Y Kiyotsuka, Y Ueno, Y Miyazawa, H Kurata, T Ogata, T Deguchi, ... Bioorganic & medicinal chemistry letters 20 (2), 746-754, 2010 | 33 | 2010 |
Novel benzoylpiperidine-based stearoyl-CoA desaturase-1 inhibitors: Identification of 6-[4-(2-methylbenzoyl) piperidin-1-yl] pyridazine-3-carboxylic acid (2-hydroxy-2-pyridin-3 … Y Uto, T Ogata, Y Kiyotsuka, Y Ueno, Y Miyazawa, H Kurata, T Deguchi, ... Bioorganic & medicinal chemistry letters 20 (1), 341-345, 2010 | 32 | 2010 |
The median preoptic nucleus is involved in the facilitation of heat-escape/cold-seeking behavior during systemic salt loading in rats M Konishi, K Kanosue, M Kano, A Kobayashi, K Nagashima American Journal of Physiology-Regulatory, Integrative and Comparative …, 2007 | 25 | 2007 |
Synthesis and biological evaluation of novel chiral diazepine derivatives as bombesin receptor subtype-3 (BRS-3) agonists incorporating an antedrug approach T Matsufuji, K Shimada, S Kobayashi, M Ichikawa, A Kawamura, ... Bioorganic & Medicinal Chemistry 23 (1), 89-104, 2015 | 24 | 2015 |
Systemic salt loading decreases body temperature and increases heat‐escape/cold‐seeking behaviour via the central AT1 and V1 receptors in rats M Konishi, K Nagashima, K Kanosue The Journal of physiology 545 (1), 289-296, 2002 | 21 | 2002 |
Discovery of novel pyridazine derivatives as glucose transporter type 4 (GLUT4) translocation activators T Tsuji, M Yamaguchi, J Kuroyanagi, S Furuzono, M Konishi, K Terayama, ... Bioorganic & Medicinal Chemistry Letters 29 (14), 1785-1790, 2019 | 20 | 2019 |
Increased heat-escape/cold-seeking behavior following hypertonic saline injection in rats K Nagashima, S Nakai, M Konishi, L Su, K Kanosue American Journal of Physiology-Regulatory, Integrative and Comparative …, 2001 | 20 | 2001 |