Structure of the human receptor tyrosine kinase met in complex with the Listeria invasion protein InlB HH Niemann, V Jäger, PJG Butler, J van den Heuvel, S Schmidt, ... Cell 130 (2), 235-246, 2007 | 197 | 2007 |
Extracellular NAD+ enhances PARP-dependent DNA repair capacity independently of CD73 activity A Wilk, F Hayat, R Cunningham, J Li, S Garavaglia, L Zamani, DM Ferraris, ... Scientific reports 10 (1), 651, 2020 | 77 | 2020 |
Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment R Miggiano, M Rizzi, DM Ferraris Pathogens 9 (5), 385, 2020 | 76 | 2020 |
Ligand-mediated dimerization of the Met receptor tyrosine kinase by the bacterial invasion protein InlB DM Ferraris, E Gherardi, Y Di, DW Heinz, HH Niemann Journal of molecular biology 395 (3), 522-532, 2010 | 59 | 2010 |
Single-molecule photobleaching reveals increased MET receptor dimerization upon ligand binding in intact cells MS Dietz, D Haße, DM Ferraris, A Göhler, HH Niemann, M Heilemann BMC biophysics 6, 1-9, 2013 | 56 | 2013 |
Imidazo[1,2-a]pyridine Derivatives as Aldehyde Dehydrogenase Inhibitors: Novel Chemotypes to Target Glioblastoma Stem Cells L Quattrini, ELM Gelardi, V Coviello, S Sartini, DM Ferraris, M Mori, ... Journal of Medicinal Chemistry 63 (9), 4603-4616, 2020 | 54 | 2020 |
Development of Potent Inhibitors of the Mycobacterium tuberculosis Virulence Factor Zmp1 and Evaluation of Their Effect on Mycobacterial Survival inside … M Paolino, M Brindisi, A Vallone, S Butini, G Campiani, C Nannicini, ... ChemMedChem 13 (5), 422-430, 2018 | 42 | 2018 |
Mycobacterium tuberculosis Molecular Determinants of Infection, Survival Strategies, and Vulnerable Targets DM Ferraris, R Miggiano, F Rossi, M Rizzi Pathogens 7 (1), 17, 2018 | 41 | 2018 |
Crystal structure of Mycobacterium tuberculosis zinc-dependent metalloprotease-1 (Zmp1), a metalloprotease involved in pathogenicity DM Ferraris, D Sbardella, A Petrera, S Marini, B Amstutz, M Coletta, ... Journal of Biological Chemistry 286 (37), 32475-32482, 2011 | 41 | 2011 |
The synthesis of kynurenic acid in mammals: An updated kynurenine aminotransferase structural KATalogue F Rossi, R Miggiano, DM Ferraris, M Rizzi Frontiers in molecular biosciences 6, 7, 2019 | 40 | 2019 |
Expanding benzoxazole-based inosine 5′-monophosphate dehydrogenase (IMPDH) inhibitor structure–activity as potential antituberculosis agents S Chacko, HIM Boshoff, V Singh, DM Ferraris, DR Gollapalli, M Zhang, ... Journal of medicinal chemistry 61 (11), 4739-4756, 2018 | 40 | 2018 |
A selective competitive inhibitor of aldehyde dehydrogenase 1A3 hinders cancer cell growth, invasiveness and stemness in vitro ELM Gelardi, G Colombo, F Picarazzi, DM Ferraris, A Mangione, ... Cancers 13 (2), 356, 2021 | 36 | 2021 |
Functional characterization of the Mycobacterium tuberculosis zinc metallopeptidase Zmp1 and identification of potential substrates A Petrera, B Amstutz, M Gioia, J Hähnlein, A Baici, P Selchow, ... Biological chemistry 393 (7), 631-640, 2012 | 33 | 2012 |
Structures of citrate synthase and malate dehydrogenase of Mycobacterium tuberculosis DM Ferraris, R Spallek, W Oehlmann, M Singh, M Rizzi Proteins: Structure, Function, and Bioinformatics 83 (2), 389-394, 2015 | 32 | 2015 |
Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis S Donini, DM Ferraris, R Miggiano, A Massarotti, M Rizzi Scientific reports 7 (1), 1180, 2017 | 30 | 2017 |
Synthesis and structure–activity relationship of 1-(5-isoquinolinesulfonyl) piperazine analogues as inhibitors of Mycobacterium tuberculosis IMPDH V Singh, A Pacitto, S Donini, DM Ferraris, S Boros, E Illyés, B Szokol, ... European journal of medicinal chemistry 174, 309-329, 2019 | 28 | 2019 |
Discovery of the first potent and selective Mycobacterium tuberculosis Zmp1 inhibitor M Mori, F Moraca, D Deodato, DM Ferraris, P Selchow, P Sander, M Rizzi, ... Bioorganic & medicinal chemistry letters 24 (11), 2508-2511, 2014 | 28 | 2014 |
Hit discovery of Mycobacterium tuberculosis inosine 5′-monophosphate dehydrogenase, GuaB2, inhibitors NU Sahu, V Singh, DM Ferraris, M Rizzi, PS Kharkar Bioorganic & medicinal chemistry letters 28 (10), 1714-1718, 2018 | 27 | 2018 |
Biochemical and structural investigations on phosphoribosylpyrophosphate synthetase from Mycobacterium smegmatis S Donini, S Garavaglia, DM Ferraris, R Miggiano, S Mori, K Shibayama, ... PLoS One 12 (4), e0175815, 2017 | 23 | 2017 |
Design, synthesis, SAR and biological investigation of 3-(carboxymethyl) rhodanine and aminothiazole inhibitors of Mycobacterium tuberculosis Zmp1 M Mori, D Deodato, M Kasula, DM Ferraris, A Sanna, A De Logu, M Rizzi, ... Bioorganic & Medicinal Chemistry Letters 28 (4), 637-641, 2018 | 22 | 2018 |