关注
Esteban Orellana
Esteban Orellana
Geisel Medical School at Dartmouth College
在 dartmouth.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Sulforhodamine B (SRB) assay in cell culture to investigate cell proliferation
EA Orellana, AL Kasinski
Bio-protocol 6 (21), e1984-e1984, 2016
4122016
A combinatorial microRNA therapeutics approach to suppressing non-small cell lung cancer
AL Kasinski, K Kelnar, C Stahlhut, E Orellana, J Zhao, E Shimer, S Dysart, ...
Oncogene 34 (27), 3547-3555, 2015
2372015
METTL1-mediated m7G modification of Arg-TCT tRNA drives oncogenic transformation
EA Orellana, Q Liu, E Yankova, M Pirouz, E De Braekeleer, W Zhang, ...
Molecular cell 81 (16), 3323-3338. e14, 2021
1912021
MicroRNAs in cancer: a historical perspective on the path from discovery to therapy
EA Orellana, AL Kasinski
Cancers 7 (3), 1388-1405, 2015
1492015
METTL4 is an snRNA m6Am methyltransferase that regulates RNA splicing
H Chen, L Gu, EA Orellana, Y Wang, J Guo, QI Liu, L Wang, Z Shen, H Wu, ...
Cell research 30 (6), 544-547, 2020
1082020
Synthetic lethality of Wnt pathway activation and asparaginase in drug-resistant acute leukemias
L Hinze, M Pfirrmann, S Karim, J Degar, C McGuckin, D Vinjamur, ...
Cancer cell 35 (4), 664-676. e7, 2019
952019
FolamiRs: Ligand-targeted, vehicle-free delivery of microRNAs for the treatment of cancer
EA Orellana, S Tenneti, L Rangasamy, LT Lyle, PS Low, AL Kasinski
Science translational medicine 9 (401), eaam9327, 2017
882017
tRNA dysregulation and disease
EA Orellana, E Siegal, RI Gregory
Nature Reviews Genetics 23 (11), 651-664, 2022
682022
Biosynthesis and genomic analysis of medium-chain hydrocarbon production by the endophytic fungal isolate Nigrograna mackinnonii E5202H
JJ Shaw, DJ Spakowicz, RS Dalal, JH Davis, NA Lehr, BF Dunican, ...
Applied microbiology and biotechnology 99, 3715-3728, 2015
572015
Structural basis of regulated m7G tRNA modification by METTL1–WDR4
J Li, L Wang, Q Hahn, RP Nowak, T Viennet, EA Orellana, ...
Nature 613 (7943), 391-397, 2023
372023
Enhancing microRNA activity through increased endosomal release mediated by nigericin
EA Orellana, AM Abdelaal, L Rangasamy, S Tenneti, S Myoung, PS Low, ...
Molecular Therapy-Nucleic Acids 16, 505-518, 2019
302019
In tobacco BY-2 cells xyloglucan oligosaccharides alter the expression of genes involved in cell wall metabolism, signalling, stress responses, cell division and …
L González-Pérez, L Perrotta, A Acosta, E Orellana, N Spadafora, L Bruno, ...
Molecular biology reports 41, 6803-6816, 2014
292014
New Mechanism for Release of Endosomal Contents: Osmotic Lysis via Nigericin-Mediated K+/H+ Exchange
L Rangasamy, V Chelvam, AK Kanduluru, M Srinivasarao, NA Bandara, ...
Bioconjugate chemistry 29 (4), 1047-1059, 2018
282018
Identification and validation of microRNAs that synergize with miR-34a–a basis for combinatorial microRNA therapeutics
EA Orellana, C Li, A Lisevick, AL Kasinski
Cell Cycle 18 (15), 1798-1811, 2019
212019
Sulforhodamine B (SRB) assay in cell culture to investigate cell proliferation. Bio Protoc. 2016
EA Orellana, AL Kasinski
141984
No vehicle, no problem
EA Orellana, AL Kasinski
Oncotarget 8 (57), 96470, 2017
52017
Selective targeting of chemically modified miR-34a to prostate cancer using a small molecule ligand and an endosomal escape agent
AM Abdelaal, IS Sohal, SG Iyer, K Sudarshan, EA Orellana, KE Ozcan, ...
Molecular Therapy-Nucleic Acids 35 (2), 2024
2024
A noncatalytic role for mettl1 in oncogenic translation in soft tissue sarcoma
RH Ali, B Silverman, EA Orellana, A Kennedy, C Bowers, A Gutierrez, ...
Cancer Research 83 (7_Supplement), 3500-3500, 2023
2023
S859 GENOME‐WIDE CRISPR‐CAS9 SCREEN REVEALS SYNTHETIC LETHALITY OF WNT PATHWAY ACTIVATION AND ASPARAGINASE IN DRUG‐RESISTANT ACUTE LEUKEMIAS
L Hinze, M Pfirrmann, S Karim, J Degar, C McGuckin, D Vinjamur, ...
HemaSphere 3, 384, 2019
2019
Enhancing miRNA therapeutic efficacy through combinatorial targeting and vehicle free delivery
EA Orellana
Purdue University, 2018
2018
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