Structural snapshots of human HDAC8 provide insights into the class I histone deacetylases JR Somoza, RJ Skene, BA Katz, C Mol, JD Ho, AJ Jennings, C Luong, ... Structure 12 (7), 1325-1334, 2004 | 842 | 2004 |
Flexibility of the NSAID binding site in the structure of human cyclooxygenase-2 C Luong, A Miller, J Barnett, J Chow, C Ramesha, MF Browner Nature structural biology 3 (11), 927-933, 1996 | 793 | 1996 |
Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies K Newton, ML Matsumoto, IE Wertz, DS Kirkpatrick, JR Lill, J Tan, ... Cell 134 (4), 668-678, 2008 | 660 | 2008 |
K11-linked polyubiquitination in cell cycle control revealed by a K11 linkage-specific antibody ML Matsumoto, KE Wickliffe, KC Dong, C Yu, I Bosanac, D Bustos, L Phu, ... Molecular cell 39 (3), 477-484, 2010 | 479 | 2010 |
Effect of outpatient pharmacists' non‐dispensing roles on patient outcomes and prescribing patterns N Nkansah, O Mostovetsky, C Yu, T Chheng, J Beney, CM Bond, L Bero Cochrane database of systematic reviews, 2010 | 478 | 2010 |
Specific Btk inhibition suppresses B cell–and myeloid cell–mediated arthritis JA Di Paolo, T Huang, M Balazs, J Barbosa, KH Barck, BJ Bravo, ... Nature chemical biology 7 (1), 41-50, 2011 | 386 | 2011 |
USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria CN Cunningham, JM Baughman, L Phu, JS Tea, C Yu, M Coons, ... Nature cell biology 17 (2), 160-169, 2015 | 336 | 2015 |
Crystal structures of MMP-1 and-13 reveal the structural basis for selectivity of collagenase inhibitors B Lovejoy, AR Welch, S Carr, C Luong, C Broka, R Hendricks, ... Nature structural biology 6 (3), 217-221, 1999 | 313 | 1999 |
Ubiquitin binding to A20 ZnF4 is required for modulation of NF-κB signaling I Bosanac, IE Wertz, B Pan, C Yu, S Kusam, C Lam, L Phu, Q Phung, ... Molecular cell 40 (4), 548-557, 2010 | 220 | 2010 |
Activation mechanism of oncogenic deletion mutations in BRAF, EGFR, and HER2 SA Foster, DM Whalen, A Özen, MJ Wongchenko, JP Yin, I Yen, ... Cancer cell 29 (4), 477-493, 2016 | 211 | 2016 |
Design of potent selective zinc-mediated serine protease inhibitors BA Katz, JM Clark, JS Finer-Moore, TE Jenkins, CR Johnson, MJ Ross, ... Nature 391 (6667), 608-612, 1998 | 201 | 1998 |
Development of serine protease inhibitors displaying a multicentered short (< 2.3 Å) hydrogen bond binding mode: Inhibitors of urokinase-type plasminogen activator and factor Xa E Verner, BA Katz, JR Spencer, D Allen, J Hataye, W Hruzewicz, HC Hui, ... Journal of medicinal chemistry 44 (17), 2753-2771, 2001 | 162 | 2001 |
Battling Btk mutants with noncovalent inhibitors that overcome Cys481 and Thr474 mutations AR Johnson, PB Kohli, A Katewa, E Gogol, LD Belmont, R Choy, ... ACS chemical biology 11 (10), 2897-2907, 2016 | 147 | 2016 |
Phosphorylation of Dishevelled by protein kinase RIPK4 regulates Wnt signaling XD Huang, JC McGann, BY Liu, RN Hannoush, JR Lill, V Pham, ... Science 339 (6126), 1441-1445, 2013 | 133 | 2013 |
Engineering and structural characterization of a linear polyubiquitin-specific antibody ML Matsumoto, KC Dong, C Yu, L Phu, X Gao, RN Hannoush, ... Journal of molecular biology 418 (3-4), 134-144, 2012 | 123 | 2012 |
Structural basis for selectivity of a small molecule, S1-binding, submicromolar inhibitor of urokinase-type plasminogen activator BA Katz, R Mackman, C Luong, K Radika, A Martelli, PA Sprengeler, ... Chemistry & biology 7 (4), 299-312, 2000 | 122 | 2000 |
Exploiting subsite S1 of trypsin-like serine proteases for selectivity: potent and selective inhibitors of urokinase-type plasminogen activator RL Mackman, BA Katz, JG Breitenbucher, HC Hui, E Verner, C Luong, ... Journal of medicinal chemistry 44 (23), 3856-3871, 2001 | 113 | 2001 |
The structure of the extracellular region of human hepsin reveals a serine protease domain and a novel scavenger receptor cysteine-rich (SRCR) domain JR Somoza, JD Ho, C Luong, M Ghate, PA Sprengeler, K Mortara, ... Structure 11 (9), 1123-1131, 2003 | 105 | 2003 |
Engineering inhibitors highly selective for the S1 sites of Ser190 trypsin-like serine protease drug targets BA Katz, PA Sprengeler, C Luong, E Verner, K Elrod, M Kirtley, J Janc, ... Chemistry & Biology 8 (11), 1107-1121, 2001 | 95 | 2001 |
Preparation of distinct ubiquitin chain reagents of high purity and yield KC Dong, E Helgason, C Yu, L Phu, DP Arnott, I Bosanac, DM Compaan, ... Structure 19 (8), 1053-1063, 2011 | 88 | 2011 |