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Fashe
Fashe
UNC Eshelman School of Pharmacy
在 email.unc.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Species-Specific Differences in the in Vitro Metabolism of Lasiocarpine
MM Fashe, RO Juvonen, A Petsalo, J Rasanen, M Pasanen
Chemical research in toxicology 28 (10), 2034-2044, 2015
352015
In Silico Prediction of the Site of Oxidation by Cytochrome P450 3A4 That Leads to the Formation of the Toxic Metabolites of Pyrrolizidine Alkaloids
MM Fashe, RO Juvonen, A Petsalo, J Vepsäläinen, M Pasanen, ...
Chemical Research in Toxicology 28 (4), 702-710, 2015
312015
Identification of a New Reactive Metabolite of Pyrrolizidine Alkaloid Retrorsine: (3H-Pyrrolizin-7-yl)methanol
MM Fashe, RO Juvonen, A Petsalo, M Rahnasto-Rilla, S Auriola, ...
Chemical Research in Toxicology 27 (11), 1950-1957, 2014
252014
Nuclear receptor CAR-ERα signaling regulates the estrogen sulfotransferase gene in the liver
MJ Yi, M Fashe, S Arakawa, R Moore, T Sueyoshi, M Negishi
Scientific Reports 10 (1), 5001, 2020
172020
Rational design of novel CYP2A6 inhibitors
N Tani, RO Juvonen, H Raunio, M Fashe, J Leppänen, B Zhao, ...
Bioorganic & medicinal chemistry 22 (23), 6655-6664, 2014
172014
Phenobarbital‐induced phosphorylation converts nuclear receptor RORα from a repressor to an activator of the estrogen sulfotransferase gene Sult1e1 in mouse …
M Fashe, T Hashiguchi, MJ Yi, R Moore, M Negishi
FEBS letters 592 (16), 2760-2768, 2018
142018
The impact of pregnancy on antihypertensive drug metabolism and pharmacokinetics: Current status and future directions
IR Mulrenin, JE Garcia, MM Fashe, MS Loop, MA Daubert, RP Urrutia, ...
Expert opinion on drug metabolism & toxicology 17 (11), 1261-1279, 2021
132021
Gendered vulnerability, perception and adaptation options of smallholder farmers to climate change in eastern Ethiopia
MM Maja, AA Idiris, AT Terefe, MM Fashe
Earth Systems and Environment 7 (1), 189-209, 2023
112023
Impact of pregnancy related hormones on drug metabolizing enzyme and transport protein concentrations in human hepatocytes
MM Fashe, JK Fallon, TA Miner, JB Tiley, PC Smith, CR Lee
Frontiers in Pharmacology 13, 1004010, 2022
102022
Sex-specific expression mechanism of hepatic estrogen inactivating enzyme and transporters in diabetic women
M Fashe, MJ Yi, T Sueyoshi, M Negishi
Biochemical pharmacology 190, 114662, 2021
92021
A phosphorylation-deficient mutant of retinoid X receptor α at Thr 167 alters fasting response and energy metabolism in mice
T Sueyoshi, T Sakuma, S Shindo, M Fashe, T Kanayama, M Ray, R Moore, ...
Laboratory Investigation 99 (10), 1470-1483, 2019
82019
Pregnancy related hormones increase CYP3A mediated buprenorphine metabolism in human hepatocytes: A comparison to CYP3A substrates nifedipine and midazolam
MM Fashe, TA Miner, JK Fallon, AP Schauer, C Sykes, PC Smith, CR Lee
Frontiers in pharmacology 14, 1218703, 2023
42023
Ser100-phosphorylated RORα orchestrates CAR and HNF4α to form active chromatin complex in response to phenobarbital to regulate induction of CYP2B6
M Fashe, T Hashiguchi, M Negishi, T Sueyoshi
Molecular Pharmacology 97 (3), 191-201, 2020
42020
New glutathione conjugate of pyrrolizidine alkaloids produced by human cytosolic enzyme‐dependent reactions in vitro
F Muluneh, MR Häkkinen, R El‐Dairi, M Pasanen, RO Juvonen
Rapid Communications in Mass Spectrometry 32 (16), 1344-1352, 2018
42018
In vitro sulfonation of 7-hydroxycoumarin derivatives in liver cytosol of human and six animal species
RO Juvonen, O Pentikäinen, J Huuskonen, J Timonen, O Kärkkäinen, ...
Xenobiotica 50 (8), 885-893, 2020
32020
Impact of Sex and Pregnancy on Hepatic CYP3A4 Expression and Activity in a Humanized Mouse Model
MM Fashe, TA Miner, VL Collazo, JT Grieco, JK Fallon, KD Jackson, ...
Drug Metabolism and Disposition, 100025, 2024
2024
Impact of Pregnancy on the Pharmacokinetics and Metabolism of Nicotinamide in Humans
MM Fashe, TV Le, MN Gower, IR Mulrenin, KF Dorman, S Smith, ...
Clinical Pharmacology & Therapeutics 115 (3), 556-564, 2024
2024
Nuclear Receptors CAR, ERα and RORα Communicate via Phosphorylation to Differentially Regulate the SULT1E1 Gene Expression in Diabetic and Nondiabetic Human Livers
MM Fashe, M Negishi
The FASEB Journal 34 (S1), 1-1, 2020
2020
Rational design of novel CYP2A6 inhibitors
H Raunio, N Tani, R Juvonen, M Fashe, J Leppänen, B Zhao, S Miksys, ...
Toxicology Letters, S181-S182, 2013
2013
Phenobarbital-induced phosphorylation converts nuclear receptor RORa from a repressor to an activator of the estrogen sulfotransferase gene Sult1e1 in mouse livers
M Fashe, T Hashiguchi, MJ Yi, R Moore, M Negishi
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