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Eric Ortlund
Eric Ortlund
Emory University School of Medicine
在 emory.edu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Rapid generation of neutralizing antibody responses in COVID-19 patients
MS Suthar, MG Zimmerman, RC Kauffman, G Mantus, SL Linderman, ...
Cell Reports Medicine 1 (3), 2020
5562020
Crystal structure of an ancient protein: evolution by conformational epistasis
EA Ortlund, JT Bridgham, MR Redinbo, JW Thornton
Science 317 (5844), 1544-1548, 2007
5032007
Glucocorticoid receptor control of transcription: precision and plasticity via allostery
ER Weikum, MT Knuesel, EA Ortlund, KR Yamamoto
Nature reviews Molecular cell biology 18 (3), 159-174, 2017
4752017
The nuclear receptor superfamily: A structural perspective
ER Weikum, X Liu, EA Ortlund
Protein Science 27 (11), 1876-1892, 2018
4552018
An epistatic ratchet constrains the direction of glucocorticoid receptor evolution
JT Bridgham, EA Ortlund, JW Thornton
Nature 461 (7263), 515-519, 2009
4522009
The structure, function and evolution of proteins that bind DNA and RNA
WH Hudson, EA Ortlund
Nature reviews Molecular cell biology 15 (11), 749-760, 2014
3742014
Evolutionary history and metabolic insights of ancient mammalian uricases
JT Kratzer, MA Lanaspa, MN Murphy, C Cicerchi, CL Graves, PA Tipton, ...
Proceedings of the National Academy of Sciences 111 (10), 3763-3768, 2014
3692014
A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects
JM Lee, YK Lee, JL Mamrosh, SA Busby, PR Griffin, MC Pathak, ...
Nature 474 (7352), 506-510, 2011
2852011
Functional anatomy of phospholipid binding and regulation of phosphoinositide homeostasis by proteins of the sec14 superfamily
G Schaaf, EA Ortlund, KR Tyeryar, CJ Mousley, KE Ile, TA Garrett, J Ren, ...
Molecular cell 29 (2), 191-206, 2008
2682008
Protein evolution by molecular tinkering: diversification of the nuclear receptor superfamily from a ligand-dependent ancestor
JT Bridgham, GN Eick, C Larroux, K Deshpande, MJ Harms, ...
PLoS biology 8 (10), e1000497, 2010
2612010
Lysosomal signaling molecules regulate longevity in Caenorhabditis elegans
A Folick, HD Oakley, Y Yu, EH Armstrong, M Kumari, L Sanor, DD Moore, ...
Science 347 (6217), 83-86, 2015
2572015
The structural basis of direct glucocorticoid-mediated transrepression
WH Hudson, C Youn, EA Ortlund
Nature structural & molecular biology 20 (1), 53-58, 2013
2372013
Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP
EA Ortlund, Y Lee, IH Solomon, JM Hager, R Safi, Y Choi, Z Guan, ...
Nature structural & molecular biology 12 (4), 357-363, 2005
2282005
APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes
JW Blanchard, LA Akay, J Davila-Velderrain, D von Maydell, H Mathys, ...
Nature 611 (7937), 769-779, 2022
2182022
Molecular transducers of physical activity consortium (MoTrPAC): mapping the dynamic responses to exercise
JA Sanford, CD Nogiec, ME Lindholm, JN Adkins, D Amar, S Dasari, ...
Cell 181 (7), 1464-1474, 2020
1942020
Identification of a lipid scrambling domain in ANO6/TMEM16F
K Yu, JM Whitlock, K Lee, EA Ortlund, Y Yuan Cui, HC Hartzell
Elife 4, e06901, 2015
1872015
Evolution of minimal specificity and promiscuity in steroid hormone receptors
GN Eick, JK Colucci, MJ Harms, EA Ortlund, JW Thornton
PLoS genetics 8 (11), e1003072, 2012
1432012
Structural basis for ligand regulation of the fatty acid-binding protein 5, peroxisome proliferator-activated receptor β/δ (FABP5-PPARβ/δ) signaling pathway
EH Armstrong, D Goswami, PR Griffin, N Noy, EA Ortlund
Journal of Biological Chemistry 289 (21), 14941-14954, 2014
1422014
Hydrophobic environment is a key factor for the stability of thermophilic proteins
MM Gromiha, MC Pathak, K Saraboji, EA Ortlund, EA Gaucher
Proteins: Structure, Function, and Bioinformatics 81 (4), 715-721, 2013
1412013
Evolution of DNA specificity in a transcription factor family produced a new gene regulatory module
AN McKeown, JT Bridgham, DW Anderson, MN Murphy, EA Ortlund, ...
Cell 159 (1), 58-68, 2014
1272014
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