A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera C James, V Ugo, JP Le Couédic, J Staerk, F Delhommeau, C Lacout, ... nature 434 (7037), 1144-1148, 2005 | 4589 | 2005 |
Mutation in TET2 in Myeloid Cancers F Delhommeau, S Dupont, VD Valle, C James, S Trannoy, A Massé, ... New England Journal of Medicine 360 (22), 2289-2301, 2009 | 2176 | 2009 |
TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis C Quivoron, L Couronné, V Della Valle, CK Lopez, I Plo, O Wagner-Ballon, ... Cancer cell 20 (1), 25-38, 2011 | 1014 | 2011 |
c-Mpl ligand is a humoral regulator of megakaryocytopoiesis F Wendling, E Maraskovsky, N Debili, C Florindo, M Teepe, M Titeux, ... Nature 369 (6481), 571-574, 1994 | 826 | 1994 |
Genetic basis and molecular pathophysiology of classical myeloproliferative neoplasms W Vainchenker, R Kralovics Blood, The Journal of the American Society of Hematology 129 (6), 667-679, 2017 | 672 | 2017 |
JAK/STAT signaling in hematological malignancies W Vainchenker, SN Constantinescu Oncogene 32 (21), 2601-2613, 2013 | 600 | 2013 |
Prognostic score including gene mutations in chronic myelomonocytic leukemia R Itzykson, O Kosmider, A Renneville, V Gelsi-Boyer, M Meggendorfer, ... Journal of clinical oncology 31 (19), 2428-2436, 2013 | 580 | 2013 |
JAK2V617F expression in murine hematopoietic cells leads to MPD mimicking human PV with secondary myelofibrosis C Lacout, DF Pisani, M Tulliez, FM Gachelin, W Vainchenker, JL Villeval blood 108 (5), 1652-1660, 2006 | 559 | 2006 |
TET2 mutations and their clinical correlates in polycythemia vera, essential thrombocythemia and myelofibrosis A Tefferi, A Pardanani, KH Lim, O Abdel-Wahab, TL Lasho, J Patel, ... Leukemia 23 (5), 905-911, 2009 | 535 | 2009 |
Megakaryocytic and erythrocytic lineages share specific transcription factors PH Romeo, MH Prandini, V Joulin, V Mignotte, M Prenant, W Vainchenker, ... Nature 344 (6265), 447-449, 1990 | 527 | 1990 |
New mutations and pathogenesis of myeloproliferative neoplasms W Vainchenker, F Delhommeau, SN Constantinescu, OA Bernard Blood, The Journal of the American Society of Hematology 118 (7), 1723-1735, 2011 | 522 | 2011 |
Oligodeoxynucleotides antisense to the proto-oncogene c-mpl specifically inhibit in vitro megakaryocytopoiesis N Methia, F Louache, W Vainchenker, F Wendling | 482 | 1993 |
NK cell activation by dendritic cells (DCs) requires the formation of a synapse leading to IL-12 polarization in DCs C Borg, A Jalil, D Laderach, K Maruyama, H Wakasugi, S Charrier, ... Blood 104 (10), 3267-3275, 2004 | 437 | 2004 |
Platelet formation is the consequence of caspase activation within megakaryocytes S De Botton, S Sabri, E Daugas, Y Zermati, JE Guidotti, O Hermine, ... Blood, The Journal of the American Society of Hematology 100 (4), 1310-1317, 2002 | 431 | 2002 |
Mutations of ASXL1 gene in myeloproliferative neoplasms N Carbuccia, A Murati, V Trouplin, M Brecqueville, J Adelaide, J Rey, ... Leukemia 23 (11), 2183-2186, 2009 | 429 | 2009 |
Myeloproliferative neoplasms: molecular pathophysiology, essential clinical understanding, and treatment strategies A Tefferi, W Vainchenker Journal of clinical oncology 29 (5), 573-582, 2011 | 422 | 2011 |
Specific involvement of caspases in the differentiation of monocytes into macrophages O Sordet, C Rébé, S Plenchette, Y Zermati, O Hermine, W Vainchenker, ... Blood, The Journal of the American Society of Hematology 100 (13), 4446-4453, 2002 | 392 | 2002 |
Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy M Castedo, JL Perfettini, T Roumier, A Valent, H Raslova, K Yakushijin, ... Oncogene 23 (25), 4362-4370, 2004 | 380 | 2004 |
Cloning, characterization, and functional studies of human and mouse glycoprotein VI: a platelet-specific collagen receptor from the immunoglobulin superfamily M Jandrot-Perrus, S Busfield, AH Lagrue, X Xiong, N Debili, T Chickering, ... Blood, The Journal of the American Society of Hematology 96 (5), 1798-1807, 2000 | 364 | 2000 |
Thrombopoietin receptor activation by myeloproliferative neoplasm associated calreticulin mutants I Chachoua, C Pecquet, M El-Khoury, H Nivarthi, RI Albu, C Marty, ... Blood, The Journal of the American Society of Hematology 127 (10), 1325-1335, 2016 | 363 | 2016 |