Amyloid-β pathology and APOE genotype modulate retinoid X receptor agonist activity in vivo LM Tai, KP Koster, J Luo, SH Lee, Y Wang, NC Collins, MB Aissa, ... Journal of Biological Chemistry 289 (44), 30538-30555, 2014 | 98 | 2014 |
Novel selective estrogen receptor downregulators (SERDs) developed against treatment-resistant breast cancer R Xiong, J Zhao, LM Gutgesell, Y Wang, S Lee, B Karumudi, H Zhao, Y Lu, ... Journal of medicinal chemistry 60 (4), 1325-1342, 2017 | 90 | 2017 |
Effects of aromatase inhibition versus gonadectomy on hippocampal complex amyloid pathology in triple transgenic mice CR Overk, PY Lu, YT Wang, J Choi, JW Shaw, GR Thatcher, EJ Mufson Neurobiology of disease 45 (1), 479-487, 2012 | 54 | 2012 |
Characterization of reactive intermediates generated during photolysis of 4-acetoxy-4-aryl-2, 5-cyclohexadienones: Oxenium ions and aryloxy radicals YT Wang, KJ Jin, SH Leopold, J Wang, HL Peng, MS Platz, J Xue, ... Journal of the American Chemical Society 130 (47), 16021-16030, 2008 | 48 | 2008 |
Hyperoxia-induced p47phox activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P1&2 signaling axis in lung endothelium A Harijith, S Pendyala, DL Ebenezer, AW Ha, P Fu, YT Wang, K Ma, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 311 (2 …, 2016 | 42 | 2016 |
Proteomic Profiling of Nitrosative Stress: Protein S-Oxidation Accompanies S-Nitrosylation YT Wang, SC Piyankarage, DL Williams, GRJ Thatcher ACS chemical biology 9 (3), 821-830, 2014 | 40 | 2014 |
Direct detection of a transient oxenium ion in water generated by laser flash photolysis YT Wang, J Wang, MS Platz, M Novak Journal of the American Chemical Society 129 (47), 14566-14567, 2007 | 37 | 2007 |
NO-SSRIs: nitric oxide chimera drugs incorporating a selective serotonin reuptake inhibitor S Abdul-Hay, IT Schiefer, REP Chandrasena, M Li, R Abdelhamid, ... ACS medicinal chemistry letters 2 (9), 656-661, 2011 | 24 | 2011 |
Prodrugs Bioactivated to Quinones Target NF-κB and Multiple Protein Networks: Identification of the Quinonome EN Pierce, SC Piyankarage, T Dunlap, V Litosh, MI Siklos, YT Wang, ... Chemical research in toxicology 29 (7), 1151-1159, 2016 | 19 | 2016 |
A Research Project in the Organic Instructional Laboratory Involving the Suzuki-Miyaura Cross Coupling Reaction M Novak, YT Wang, MW Ambrogio, CA Chan, HE Davis, KS Goodwin, ... Chemical Education 20, 414-418, 2007 | 17 | 2007 |
Raloxifene and desmethylarzoxifene block estrogen-induced malignant transformation of human breast epithelial cells I Kastrati, PD Edirisinghe, LPMP Hemachandra, ER Chandrasena, J Choi, ... PLoS One 6 (11), e27876, 2011 | 15 | 2011 |
Chemistry of 4-Alkylaryloxenium Ion “Precursors”: Sound and Fury Signifying Something? M Novak, AM Brinster, JN Dickhoff, JM Erb, MP Jones, SH Leopold, ... The Journal of Organic Chemistry 72 (26), 9954-9962, 2007 | 15 | 2007 |
Hydrolysis and photolysis of 4-Acetoxy-4-(benzothiazol-2-yl)-2, 5-cyclohexadien-1-one, a model anti-tumor quinol ester YT Wang, KJ Jin, LR Myers, SA Glover, M Novak The Journal of organic chemistry 74 (12), 4463-4471, 2009 | 14 | 2009 |
Design, Synthesis, Molecular Modeling, and Biological Evaluation of Novel Amine-based Histone Deacetylase Inhibitors PPA Abdelkarim H, Neelarapu R, Madriaga A, Vaidya AS, Kastrati I, Karumudi B ... ChemMedChem 12 (24), 2030-2043, 2017 | 13 | 2017 |
Unexpected hormonal activity of a catechol equine estrogen metabolite reveals reversible glutathione conjugation KW Peng, M Chang, YT Wang, Z Wang, Z Qin, JL Bolton, GRJ Thatcher Chemical research in toxicology 23 (8), 1374-1383, 2010 | 10 | 2010 |
Multiple Decomposition Pathways for the Oxenium Ion Precursor O-(4-(4′-Methylphenyl)phenyl)-N-methanesulfonylhydroxylamine YT Wang, M Novak The Journal of Organic Chemistry 74 (20), 7697-7706, 2009 | 7 | 2009 |
Nitrogen Oxides and Their Roles in Cancer Etiology YT Wang, DD Thomas Current Pharmacology Reports 3 (4), 151-161, 2017 | 5 | 2017 |
Aryl Nitrenium Ions in Aqueous Solution M Novak, YT Wang Nitrenes and Nitrenium Ions, 117-165, 2013 | 2 | 2013 |
Quantitative Profiling of Reversible Cysteome Modification Under Nitrosative Stress YT Wang, SC Piyankarage, GRJ Thatcher Analysis of Post-Translational Modifications and Proteolysis in Neuroscience …, 2016 | | 2016 |
Abstract P3-05-23: Novel, non-uterotrophic, selective estrogen mimics cause regression of tamoxifen-resistant breast cancer in 2D and 3D cultures and in mouse xenograft models GRJ Thatcher, R Xiong, HK Patel, J Zhao, X Liang, Y Wang, ME Molloy, ... Cancer Research 75 (9_Supplement), P3-05-23-P3-05-23, 2015 | | 2015 |