Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity CW Li, SO Lim, W Xia, HH Lee, LC Chan, CW Kuo, KH Khoo, SS Chang, ... Nature communications 7 (1), 12632, 2016 | 920 | 2016 |
p53 regulates epithelial–mesenchymal transition and stem cell properties through modulating miRNAs CJ Chang, CH Chao, W Xia, JY Yang, Y Xiong, CW Li, WH Yu, ... Nature cell biology 13 (3), 317-323, 2011 | 884 | 2011 |
PARP inhibitor upregulates PD-L1 expression and enhances cancer-associated immunosuppression S Jiao, W Xia, H Yamaguchi, Y Wei, MK Chen, JM Hsu, JL Hsu, WH Yu, ... Clinical Cancer Research 23 (14), 3711-3720, 2017 | 870 | 2017 |
Metformin promotes antitumor immunity via endoplasmic-reticulum-associated degradation of PD-L1 JH Cha, WH Yang, W Xia, Y Wei, LC Chan, SO Lim, CW Li, T Kim, ... Molecular cell 71 (4), 606-620. e7, 2018 | 587 | 2018 |
Eradication of triple-negative breast cancer cells by targeting glycosylated PD-L1 CW Li, SO Lim, EM Chung, YS Kim, AH Park, J Yao, JH Cha, W Xia, ... Cancer cell 33 (2), 187-201. e10, 2018 | 473 | 2018 |
Removal of N-linked glycosylation enhances PD-L1 detection and predicts anti-PD-1/PD-L1 therapeutic efficacy HH Lee, YN Wang, W Xia, CH Chen, KM Rau, L Ye, Y Wei, CK Chou, ... Cancer cell 36 (2), 168-178. e4, 2019 | 278 | 2019 |
IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion LC Chan, CW Li, W Xia, JM Hsu, HH Lee, JH Cha, HL Wang, WH Yang, ... The Journal of clinical investigation 129 (8), 3324-3338, 2019 | 257 | 2019 |
EGFR Signaling Enhances Aerobic Glycolysis in Triple-Negative Breast Cancer Cells to Promote Tumor Growth and Immune Escape HMC Lim SO, Li CW, Xia W, Lee HH, Chang SS, Shen J, Hsu JL, Raftery D ... Cancer Research 76, 1284-1296, 2016 | 237 | 2016 |
TYRO3 induces anti–PD-1/PD-L1 therapy resistance by limiting innate immunity and tumoral ferroptosis Z Jiang, SO Lim, M Yan, JL Hsu, J Yao, Y Wei, SS Chang, H Yamaguchi, ... The Journal of clinical investigation 131 (8), 2021 | 181 | 2021 |
COPI-mediated retrograde trafficking from the Golgi to the ER regulates EGFR nuclear transport YN Wang, H Wang, H Yamaguchi, HJ Lee, HH Lee, MC Hung Biochemical and biophysical research communications 399 (4), 498-504, 2010 | 172 | 2010 |
p53 acetylation is crucial for its transcription-independent proapoptotic functions H Yamaguchi, NT Woods, LG Piluso, HH Lee, J Chen, KN Bhalla, ... Journal of Biological Chemistry 284 (17), 11171-11183, 2009 | 153 | 2009 |
The translocon Sec61β localized in the inner nuclear membrane transports membrane-embedded EGF receptor to the nucleus YN Wang, H Yamaguchi, L Huo, Y Du, HJ Lee, HH Lee, H Wang, JM Hsu, ... Journal of Biological Chemistry 285 (49), 38720-38729, 2010 | 140 | 2010 |
PRMT1-mediated methylation of the EGF receptor regulates signaling and cetuximab response. HMC Liao HW, Hsu JM, Xia W, Wang HL, Wang YN, Chang WC, Arold ST, Chou CK ... The Journal of Clinical Investigation 125, 4529-4543, 2015 | 135 | 2015 |
The impact of PD-L1 N-linked glycosylation on cancer therapy and clinical diagnosis YN Wang, HH Lee, JL Hsu, D Yu, MC Hung Journal of biomedical science 27, 1-11, 2020 | 114 | 2020 |
Targeting glycosylated PD-1 induces potent antitumor immunity L Sun, CW Li, EM Chung, R Yang, YS Kim, AH Park, YJ Lai, Y Yang, ... Cancer research 80 (11), 2298-2310, 2020 | 111 | 2020 |
Small-molecule MMP2/MMP9 inhibitor SB-3CT modulates tumor immune surveillance by regulating PD-L1 Y Ye, X Kuang, Z Xie, L Liang, Z Zhang, Y Zhang, F Ma, Q Gao, R Chang, ... Genome medicine 12, 1-19, 2020 | 100 | 2020 |
Membrane-bound trafficking regulates nuclear transport of integral epidermal growth factor receptor (EGFR) and ErbB-2 YN Wang, HH Lee, HJ Lee, Y Du, H Yamaguchi, MC Hung Journal of Biological Chemistry 287 (20), 16869-16879, 2012 | 95 | 2012 |
Induction of the early growth response 1 gene by Epstein-Barr virus lytic transactivator Zta Y Chang, HH Lee, YT Chen, J Lu, SY Wu, CW Chen, K Takada, CH Tsai Journal of virology 80 (15), 7748-7755, 2006 | 78 | 2006 |
Angiogenin/ribonuclease 5 is an EGFR ligand and a serum biomarker for erlotinib sensitivity in pancreatic cancer YN Wang, HH Lee, CK Chou, WH Yang, Y Wei, CT Chen, J Yao, JL Hsu, ... Cancer Cell 33 (4), 752-769. e8, 2018 | 73 | 2018 |
Epidermal growth factor receptor potentiates MCM7-mediated DNA replication through tyrosine phosphorylation of Lyn kinase in human cancers TH Huang, L Huo, YN Wang, W Xia, Y Wei, SS Chang, WC Chang, ... Cancer cell 23 (6), 796-810, 2013 | 68 | 2013 |