| Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway S Yano, H Tokumitsu, TR Soderling Nature 396 (6711), 584-587, 1998 | 809 | 1998 |
| KN-62, 1-[N, O-bis (5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpiperazi ne, a specific inhibitor of Ca2+/calmodulin-dependent protein kinase II. H Tokumitsu, T Chijiwa, M Hagiwara, A Mizutani, M Terasawa, H Hidaka Journal of Biological Chemistry 265 (8), 4315-4320, 1990 | 764 | 1990 |
| Calmodulin-kinases: modulators of neuronal development and plasticity GA Wayman, YS Lee, H Tokumitsu, A Silva, TR Soderling Neuron 59 (6), 914-931, 2008 | 682 | 2008 |
| Regulation of mitogen-activated protein kinases by a calcium/calmodulin-dependent protein kinase cascade. H Enslen, H Tokumitsu, PJ Stork, RJ Davis, TR Soderling Proceedings of the National Academy of Sciences 93 (20), 10803-10808, 1996 | 390 | 1996 |
| STO-609, a specific inhibitor of the Ca2+/calmodulin-dependent protein kinase kinase H Tokumitsu, H Inuzuka, Y Ishikawa, M Ikeda, I Saji, R Kobayashi Journal of Biological Chemistry 277 (18), 15813-15818, 2002 | 324 | 2002 |
| A novel target recognition revealed by calmodulin in complex with Ca2+-calmodulin-dependent kinase kinase M Osawa, H Tokumitsu, MB Swindells, H Kurihara, M Orita, T Shibanuma, ... Nature structural biology 6 (9), 819-824, 1999 | 318 | 1999 |
| Characterization of a Ca2+/Calmodulin-dependent Protein Kinase Cascade: MOLECULAR CLONING AND EXPRESSION OF CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE (∗) H Tokumitsu, H Enslen, TR Soderling Journal of Biological Chemistry 270 (33), 19320-19324, 1995 | 297 | 1995 |
| NFATx, a novel member of the nuclear factor of activated T cells family that is expressed predominantly in the thymus ES Masuda, Y Naito, H Tokumitsu, D Campbell, F Saito, C Hannum, ... Molecular and Cellular Biology 15 (5), 2697-2706, 1995 | 259 | 1995 |
| Regulation of axonal extension and growth cone motility by calmodulin-dependent protein kinase I GA Wayman, S Kaech, WF Grant, M Davare, S Impey, H Tokumitsu, ... Journal of Neuroscience 24 (15), 3786-3794, 2004 | 225 | 2004 |
| Activation mechanisms for Ca2+/calmodulin-dependent protein kinase IV. Identification of a brain CaM-kinase IV kinase. H Tokumitsu, DA Brickey, J Glod, H Hidaka, J Sikela, TR Soderling Journal of Biological Chemistry 269 (46), 28640-28647, 1994 | 189 | 1994 |
| Identification of Mouse ULK1, a Novel Protein Kinase Structurally Related toC. elegansUNC-51 J Yan, H Kuroyanagi, A Kuroiwa, Y Matsuda, H Tokumitsu, T Tomoda, ... Biochemical and biophysical research communications 246 (1), 222-227, 1998 | 181 | 1998 |
| Requirements for Calcium and Calmodulin in the Calmodulin Kinase Activation Cascade (∗) H Tokumitsu, TR Soderling Journal of Biological Chemistry 271 (10), 5617-5622, 1996 | 162 | 1996 |
| Analysis of CaM-kinase signaling in cells GA Wayman, H Tokumitsu, MA Davare, TR Soderling Cell calcium 50 (1), 1-8, 2011 | 156 | 2011 |
| The granulocyte-macrophage colony-stimulating factor promoter cis-acting element CLE0 mediates induction signals in T cells and is recognized by factors related to AP1 and NFAT ES Masuda, H Tokumitsu, A Tsuboi, J Shlomai, P Hung, KI Arai, N Arai Molecular and cellular biology, 1993 | 154 | 1993 |
| A CaMK cascade activates CRE‐mediated transcription in neurons of Caenorhabditis elegans Y Kimura, EE Corcoran, K Eto, K Gengyo‐Ando, M Muramatsu, ... EMBO reports, 2002 | 138 | 2002 |
| Target-induced conformational adaptation of calmodulin revealed by the crystal structure of a complex with nematode Ca2+/calmodulin-dependent kinase kinase peptide H Kurokawa, M Osawa, H Kurihara, N Katayama, H Tokumitsu, ... Journal of molecular biology 312 (1), 59-68, 2001 | 122 | 2001 |
| Inhibitory cross-talk by cAMP kinase on the calmodulin-dependent protein kinase cascade GA Wayman, H Tokumitsu, TR Soderling Journal of Biological Chemistry 272 (26), 16073-16076, 1997 | 113 | 1997 |
| A calcyclin-associated protein is a newly identified member of the Ca2+/phospholipid-binding proteins, annexin family. H Tokumitsu, A Mizutani, H Minami, R Kobayashi, H Hidaka Journal of Biological Chemistry 267 (13), 8919-8924, 1992 | 112 | 1992 |
| Compartmentalized AMPK signaling illuminated by genetically encoded molecular sensors and actuators T Miyamoto, E Rho, V Sample, H Akano, M Magari, T Ueno, K Gorshkov, ... Cell reports 11 (4), 657-670, 2015 | 107 | 2015 |
| Differential regulatory mechanism of Ca2+/calmodulin-dependent protein kinase kinase isoforms H Tokumitsu, M Iwabu, Y Ishikawa, R Kobayashi Biochemistry 40 (46), 13925-13932, 2001 | 107 | 2001 |
