Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production MJ White, K McArthur, D Metcalf, RM Lane, JC Cambier, MJ Herold, ... Cell 159 (7), 1549-1562, 2014 | 832 | 2014 |
BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis K McArthur, LW Whitehead, JM Heddleston, L Li, BS Padman, V Oorschot, ... Science 359 (6378), eaao6047, 2018 | 724 | 2018 |
TDP-43 triggers mitochondrial DNA release via mPTP to activate cGAS/STING in ALS CH Yu, S Davidson, CR Harapas, JB Hilton, MJ Mlodzianoski, ... Cell 183 (3), 636-649. e18, 2020 | 564 | 2020 |
NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells SL Masters, M Gerlic, D Metcalf, S Preston, M Pellegrini, JA O’Donnell, ... Immunity 37 (6), 1009-1023, 2012 | 321 | 2012 |
The mitochondrial apoptotic effectors BAX/BAK activate caspase-3 and-7 to trigger NLRP3 inflammasome and caspase-8 driven IL-1β activation JE Vince, D De Nardo, W Gao, AJ Vince, C Hall, K McArthur, D Simpson, ... Cell reports 25 (9), 2339-2353. e4, 2018 | 190 | 2018 |
Apoptotic caspases: multiple or mistaken identities? K McArthur, BT Kile Trends in cell biology 28 (6), 475-493, 2018 | 167 | 2018 |
Apoptosis in megakaryocytes and platelets: the life and death of a lineage K McArthur, S Chappaz, BT Kile Blood, The Journal of the American Society of Hematology 131 (6), 605-610, 2018 | 122 | 2018 |
IL‐6 promotes acute and chronic inflammatory disease in the absence of SOCS3 BA Croker, H Kiu, M Pellegrini, J Toe, S Preston, D Metcalf, JA O'donnell, ... Immunology and cell biology 90 (1), 124-129, 2012 | 74 | 2012 |
Autophagy induced during apoptosis degrades mitochondria and inhibits type I interferon secretion LM Lindqvist, D Frank, K McArthur, TA Dite, M Lazarou, JS Oakhill, BT Kile, ... Cell Death & Differentiation 25 (4), 784-796, 2018 | 50 | 2018 |
Translation inhibitors induce cell death by multiple mechanisms and Mcl-1 reduction is only a minor contributor LM Lindqvist, I Vikström, JM Chambers, K McArthur, M Ann Anderson, ... Cell death & disease 3 (10), e409-e409, 2012 | 50 | 2012 |
Activation of cGAS-dependent antiviral responses by DNA intercalating agents G Pépin, C Nejad, BJ Thomas, J Ferrand, K McArthur, PG Bardin, ... Nucleic acids research 45 (1), 198-205, 2017 | 43 | 2017 |
A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis MF van Delft, S Chappaz, Y Khakham, CT Bui, MA Debrincat, KN Lowes, ... Nature chemical biology 15 (11), 1057-1066, 2019 | 38 | 2019 |
BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis. Science 359, eaao6047 K McArthur, LW Whitehead, JM Heddleston, L Li, BS Padman, V Oorschot, ... | 30 | 2018 |
The reinvention of twentieth century microscopy for three‐dimensional imaging LW Whitehead, K McArthur, ND Geoghegan, KL Rogers Immunology and Cell Biology 95 (6), 520-524, 2017 | 27 | 2017 |
HSP90 Inhibition Suppresses Lipopolysaccharide-Induced Lung Inflammation In Vivo A Lilja, CE Weeden, K McArthur, T Nguyen, A Donald, ZX Wong, ... PLoS One 10 (1), e0114975, 2015 | 25 | 2015 |
Pharmacologic reduction of mitochondrial iron triggers a noncanonical BAX/BAK-dependent cell death S Garciaz, AA Guirguis, S Müller, FC Brown, YC Chan, A Motazedian, ... Cancer Discovery 12 (3), 774-791, 2022 | 21 | 2022 |
Epigenetic activation of plasmacytoid DCs drives IFNAR-dependent therapeutic differentiation of AML JM Salmon, I Todorovski, KL Stanley, C Bruedigam, CJ Kearney, ... Cancer Discovery 12 (6), 1560-1579, 2022 | 14 | 2022 |
Apoptotic mitochondria prime anti-tumour immunity K McArthur, BT Kile Cell death discovery 6 (1), 98, 2020 | 13 | 2020 |
Defining a therapeutic window for kinase inhibitors in leukemia to avoid neutropenia K McArthur, AA D’Cruz, D Segal, K Lackovic, AF Wilks, JA O’Donnell, ... Oncotarget 8 (35), 57948, 2017 | 5 | 2017 |
Homeostatic apoptosis prevents competition-induced atrophy in follicular B cells S Chappaz, K McArthur, L Kealy, CW Law, M Tailler, RM Lane, ... Cell Reports 36 (3), 2021 | 3 | 2021 |