A community-driven global reconstruction of human metabolism I Thiele, N Swainston, RMT Fleming, A Hoppe, S Sahoo, MK Aurich, ... Nature biotechnology 31 (5), 419, 2013 | 1184 | 2013 |
Distinguishing enzyme structures from non-enzymes without alignments PD Dobson, AJ Doig Journal of molecular biology 330 (4), 771-783, 2003 | 720 | 2003 |
A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology MJ Herrgård, N Swainston, P Dobson, WB Dunn, KY Arga, M Arvas, ... Nature biotechnology 26 (10), 1155, 2008 | 679 | 2008 |
Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule? PD Dobson, DB Kell Nature reviews Drug discovery 7 (3), 205, 2008 | 562 | 2008 |
Mass spectrometry tools and metabolite-specific databases for molecular identification in metabolomics M Brown, WB Dunn, P Dobson, Y Patel, CL Winder, S Francis-McIntyre, ... Analyst 134 (7), 1322-1332, 2009 | 320 | 2009 |
Recon 2.2: from reconstruction to model of human metabolism N Swainston, K Smallbone, H Hefzi, PD Dobson, J Brewer, M Hanscho, ... Metabolomics 12 (7), 109, 2016 | 311 | 2016 |
Predicting enzyme class from protein structure without alignments PD Dobson, AJ Doig Journal of molecular biology 345 (1), 187-199, 2005 | 209 | 2005 |
Pharmaceutical drug transport: the issues and the implications that it is essentially carrier-mediated only DB Kell, PD Dobson, SG Oliver Drug discovery today 16 (15-16), 704-714, 2011 | 203 | 2011 |
The promiscuous binding of pharmaceutical drugs and their transporter-mediated uptake into cells: what we (need to) know and how we can do so DB Kell, PD Dobson, E Bilsland, SG Oliver Drug discovery today 18 (5-6), 218-239, 2013 | 162 | 2013 |
‘Metabolite-likeness’ as a criterion in the design and selection of pharmaceutical drug libraries PD Dobson, Y Patel, DB Kell Drug Discovery Today 14 (1-2), 31-40, 2009 | 149 | 2009 |
Further developments towards a genome-scale metabolic model of yeast PD Dobson, K Smallbone, D Jameson, E Simeonidis, K Lanthaler, P Pir, ... BMC Systems Biology 4 (1), 145, 2010 | 141 | 2010 |
Integration of metabolic databases for the reconstruction of genome-scale metabolic networks K Radrich, Y Tsuruoka, P Dobson, A Gevorgyan, N Swainston, G Baart, ... BMC systems biology 4 (1), 114, 2010 | 114 | 2010 |
Implications of the Dominant Role of Transporters in Drug Uptake by Cells (Supplementary Material) PD Dobson, K Lanthaler, SG Oliver, DB Kell Current topics in medicinal chemistry 9 (2), 163-181, 2009 | 99 | 2009 |
Prediction of protein function in the absence of significant sequence similarity PD Dobson, YD Cai, BJ Stapley, AJ Doig Current medicinal chemistry 11 (16), 2135-2142, 2004 | 75 | 2004 |
Genome-wide assessment of the carriers involved in the cellular uptake of drugs: a model system in yeast K Lanthaler, E Bilsland, PD Dobson, HJ Moss, P Pir, DB Kell, SG Oliver BMC biology 9 (1), 70, 2011 | 70 | 2011 |
Length preferences and periodicity in β‐strands. Antiparallel edge β‐sheets are more likely to finish in non‐hydrogen bonded rings S Penel, RG Morrison, PD Dobson, RJ Mortishire‐Smith, AJ Doig Protein engineering 16 (12), 957-961, 2003 | 52 | 2003 |
Mining metabolites: extracting the yeast metabolome from the literature C Nobata, PD Dobson, SA Iqbal, P Mendes, J Tsujii, DB Kell, ... Metabolomics 7 (1), 94-101, 2011 | 51 | 2011 |
biochem4j: Integrated and extensible biochemical knowledge through graph databases N Swainston, R Batista-Navarro, P Carbonell, PD Dobson, M Dunstan, ... PLoS One 12 (7), e0179130, 2017 | 48 | 2017 |
The cellular uptake of pharmaceutical drugs is mainly carrier-mediated and is thus an issue not so much of biophysics but of systems biology DB Kell, PD Dobson Proc Int Beilstein Symposium on Systems Chemistry, 2009 | 25 | 2009 |
Text mining meets workflow: linking U-Compare with Taverna Y Kano, P Dobson, M Nakanishi, J Tsujii, S Ananiadou Bioinformatics 26 (19), 2486-2487, 2010 | 24 | 2010 |