Recent advances in the use of cell-penetrating peptides for medical and biological applications SB Fonseca, MP Pereira, SO Kelley Advanced drug delivery reviews 61 (11), 953-964, 2009 | 705 | 2009 |
Targeting mitochondrial DNA with a platinum-based anticancer agent SP Wisnovsky, JJ Wilson, RJ Radford, MP Pereira, MR Chan, RR Laposa, ... Chemistry & biology 20 (11), 1323-1328, 2013 | 229 | 2013 |
Lesions in Teichoic Acid Biosynthesis in Staphylococcus aureus Lead to a Lethal Gain of Function in the Otherwise Dispensable Pathway MA D'Elia, MP Pereira, YS Chung, W Zhao, A Chau, TJ Kenney, ... Journal of bacteriology 188 (12), 4183-4189, 2006 | 223 | 2006 |
Molecular vehicles for mitochondrial chemical biology and drug delivery S Rin Jean, DV Tulumello, SP Wisnovsky, EK Lei, MP Pereira, SO Kelley ACS chemical biology 9 (2), 323-333, 2014 | 145 | 2014 |
Rerouting chlorambucil to mitochondria combats drug deactivation and resistance in cancer cells SB Fonseca, MP Pereira, R Mourtada, M Gronda, KL Horton, R Hurren, ... Chemistry & biology 18 (4), 445-453, 2011 | 125 | 2011 |
Mitochondrial ATP fuels ABC transporter-mediated drug efflux in cancer chemoresistance EL Giddings, DP Champagne, MH Wu, JM Laffin, TM Thornton, ... Nature communications 12 (1), 2804, 2021 | 123 | 2021 |
Are essential genes really essential? MA D’Elia, MP Pereira, ED Brown Trends in microbiology 17 (10), 433-438, 2009 | 99 | 2009 |
Maximizing the therapeutic window of an antimicrobial drug by imparting mitochondrial sequestration in human cells MP Pereira, SO Kelley Journal of the American Chemical Society 133 (10), 3260-3263, 2011 | 74 | 2011 |
Tuning the activity of Mitochondria‐Penetrating peptides for delivery or disruption KL Horton, MP Pereira, KM Stewart, SB Fonseca, SO Kelley ChemBioChem 13 (3), 476-485, 2012 | 72 | 2012 |
High-Throughput Screening Identifies Novel Inhibitors of the Acetyltransferase Activity of Escherichia coli GlmU MP Pereira, JE Blanchard, C Murphy, SL Roderick, ED Brown Antimicrobial agents and chemotherapy 53 (6), 2306-2311, 2009 | 63 | 2009 |
Tuning the intracellular bacterial targeting of peptidic vectors. EK Lei, MP Pereira, SO Kelley Angewandte Chemie International Edition 52 (37), 2013 | 62 | 2013 |
Bifunctional catalysis by CDP-ribitol synthase: convergent recruitment of reductase and cytidylyltransferase activities in Haemophilus influenzae and Staphylococcus aureus MP Pereira, ED Brown Biochemistry 43 (37), 11802-11812, 2004 | 45 | 2004 |
Re-directing an alkylating agent to mitochondria alters drug target and cell death mechanism R Mourtada, SB Fonseca, SP Wisnovsky, MP Pereira, X Wang, R Hurren, ... PloS one 8 (4), e60253, 2013 | 43 | 2013 |
Peptide targeting of an antibiotic prodrug toward phagosome-entrapped mycobacteria MP Pereira, J Shi, SO Kelley ACS infectious diseases 1 (12), 586-592, 2015 | 42 | 2015 |
The wall teichoic acid polymerase TagF efficiently synthesizes poly (glycerol phosphate) on the TagB product lipid III MP Pereira, JW Schertzer, MA D'Elia, KP Koteva, DW Hughes, GD Wright, ... Chembiochem 9 (9), 1385-1390, 2008 | 39 | 2008 |
Duplication of Teichoic Acid Biosynthetic Genes in Staphylococcus aureus Leads to Functionally Redundant Poly(Ribitol Phosphate) Polymerases MP Pereira, MA D'Elia, J Troczynska, ED Brown Journal of bacteriology 190 (16), 5642-5649, 2008 | 33 | 2008 |
Structural modifications of mitochondria-targeted chlorambucil alter cell death mechanism but preserve MDR evasion SR Jean, MP Pereira, SO Kelley Molecular Pharmaceutics 11 (8), 2675-2682, 2014 | 27 | 2014 |
The wall teichoic acid polymerase TagF is non-processive in vitro and amenable to study using steady state kinetic analysis EWC Sewell, MP Pereira, ED Brown Journal of Biological Chemistry 284 (32), 21132-21138, 2009 | 23 | 2009 |
Isolation of DNA Aptamers for CDP‐Ribitol Synthase, and Characterization of Their Inhibitory and Structural Properties A Allali‐Hassani, MP Pereira, NK Navani, ED Brown, Y Li Chembiochem 8 (17), 2052-2057, 2007 | 11 | 2007 |
Magnetic resonance tells microbiology where to go; bacterial teichoic acid protects liquid water at sub-zero temperatures CV Rice, JR Wickham, MA Eastman, W Harrison, MP Pereira, ED Brown Instruments, Methods, and Missions for Astrobiology XI 7097, 183-192, 2008 | 8 | 2008 |