| Mechanisms of receptor tyrosine kinase activation in cancer Z Du, CM Lovly Molecular cancer 17 (1), 1-13, 2018 | 888 | 2018 |
| Epigenetic inactivation of the CpG demethylase TET1 as a DNA methylation feedback loop in human cancers L Li, C Li, H Mao, Z Du, WY Chan, P Murray, B Luo, ATC Chan, TSK Mok, ... Scientific reports 6 (1), 1-13, 2016 | 137 | 2016 |
| On-target resistance to the mutant-selective EGFR inhibitor osimertinib can develop in an allele-specific manner dependent on the original EGFR-activating mutation BP Brown, YK Zhang, D Westover, Y Yan, H Qiao, V Huang, Z Du, ... Clinical Cancer Research 25 (11), 3341-3351, 2019 | 96 | 2019 |
| Characterization of the nasopharyngeal carcinoma methylome identifies aberrant disruption of key signaling pathways and methylated tumor suppressor genes L Li, Y Zhang, Y Fan, K Sun, X Su, Z Du, SW Tsao, TKS Loh, H Sun, ... Epigenomics, 155-173, 2015 | 68 | 2015 |
| RET Germline Mutations Identified by Exome Sequencing in a Chinese Multiple Endocrine Neoplasia Type 2A/Familial Medullary Thyroid Carcinoma Family XP Qi, JM Ma, ZF Du, RB Ying, J Fei, HY Jin, JS Han, JQ Wang, XL Chen, ... PloS one 6 (5), e20353, 2011 | 60 | 2011 |
| Structure–function analysis of oncogenic EGFR Kinase Domain Duplication reveals insights into activation and a potential approach for therapeutic targeting Z Du, BP Brown, S Kim, D Ferguson, DC Pavlick, G Jayakumaran, ... Nature Communications 12 (1), 1-15, 2021 | 56 | 2021 |
| Genetic diagnosis of autosomal dominant polycystic kidney disease by targeted capture and next-generation sequencing: utility and limitations XP Qi, ZF Du, JM Ma, XL Chen, Q Zhang, J Fei, XM Wei, D Chen, HP Ke, ... Gene 516 (1), 93-100, 2013 | 45 | 2013 |
| Epigenomic characterization of a p53-regulated 3p22. 2 tumor suppressor that inhibits STAT3 phosphorylation via protein docking and is frequently methylated in esophageal and … L Li, J Xu, G Qiu, J Ying, Z Du, T Xiang, KY Wong, G Srivastava, XF Zhu, ... Theranostics 8 (1), 61, 2018 | 40 | 2018 |
| RET Proto-Oncogene Genetic Screening of Families with Multiple Endocrine Neoplasia Type 2 Optimizes Diagnostic and Clinical Management in China XP Qi, XL Chen, JM Ma, ZF Du, J Fei, CP Yang, J Cheng, QZ Song, ... Thyroid 22 (12), 1257-1265, 2012 | 40 | 2012 |
| Dickkopf-related protein 2 induces G0/G1 arrest and apoptosis through suppressing Wnt/β-catenin signaling and is frequently methylated in breast cancer J Mu, T Hui, B Shao, L Li, Z Du, L Lu, L Ye, S Li, Q Li, Q Xiao, Z Qiu, ... Oncotarget 8 (24), 39443, 2017 | 38 | 2017 |
| Prophylactic thyroidectomy for MEN 2-related medullary thyroid carcinoma based on predictive testing for RET proto-oncogene mutation and basal serum calcitonin in China XP Qi, JQ Zhao, ZF Du, RR Yang, JM Ma, J Fei, J Cheng, JS Han, HY Jin, ... European Journal of Surgical Oncology (EJSO) 39 (9), 1007-1012, 2013 | 29 | 2013 |
| Tumor suppressive BTB/POZ zinc-finger protein ZBTB28 inhibits oncogenic BCL6/ZBTB27 signaling to maintain p53 transcription in multiple carcinogenesis T Xiang, J Tang, L Li, W Peng, Z Du, X Wang, Q Li, H Xu, L Xiong, C Xu, ... Theranostics 9 (26), 8182, 2019 | 27 | 2019 |
| The epigenetic modifier CHD5 functions as a novel tumor suppressor for renal cell carcinoma and is predominantly inactivated by promoter CpG methylation Z Du, L Li, X Huang, J Jin, S Huang, Q Zhang, Q Tao Oncotarget 7 (16), 21618, 2016 | 26 | 2016 |
| Whole exome sequencing implicates PTCH1 and COL17A1 genes in ossification of the posterior longitudinal ligament of the cervical spine in Chinese patients W Wei, HL He, CY Chen, Y Zhao, HL Jiang, WT Liu, ZF Du, XL Chen, ... Genet Mol Res 13 (1), 1794-1804, 2014 | 26 | 2014 |
| A novel mutation within the 2B rod domain of keratin 9 in a Chinese pedigree with epidermolytic palmoplantar keratoderma combined with knuckle pads and camptodactyly ZF Du, W Wei, YF Wang, XL Chen, CY Chen, WT Liu, JJ Lu, LG Mao, ... European Journal of Dermatology 21 (5), 675-679, 2011 | 23 | 2011 |
| Case report: a p. C618S RET proto-oncogene germline mutation in a large Chinese pedigree with familial medullary thyroid carcinoma XP Qi, RB Ying, JM Ma, WT Liu, ZF Du, J Fei, CP Yang, QZ Song, HY Jin, ... Familial cancer 11 (1), 131-136, 2012 | 18 | 2012 |
| Detection of somatic and germline mosaicism for the LAMP2 gene mutation c. 808dupG in a Chinese family with Danon disease XL Chen, Y Zhao, HP Ke, WT Liu, ZF Du, XN Zhang Gene 507 (2), 174-176, 2012 | 14 | 2012 |
| A Small Indel Mutant Mouse Model of Epidermolytic Palmoplantar Keratoderma and Its Application to Mutant-specific shRNA Therapy YS Lyu, P Shi, XL Chen, YX Tang, YF Wang, RR Liu, XR Luan, Y Fang, ... Molecular Therapy-Nucleic Acids 5, e299, 2016 | 13 | 2016 |
| Two novel de novo mutations of KRT6A and KRT16 genes in two Chinese pachyonychia congenita pedigrees with fissured tongue or diffuse plantar keratoderma. ZF Du, CM Xu, Y Zhao, WT Liu, XL Chen, CY Chen, H Fang, HP Ke, ... European journal of dermatology: EJD 22 (4), 476-480, 2012 | 10 | 2012 |
| Genetic diagnosis of a Chinese multiple endocrine neoplasia type 2A family through whole genome sequencing ZF Du, PF Li, JQ Zhao, ZL Cao, F Li, JM Ma, XP Qi Journal of Biosciences 42 (2), 209-218, 2017 | 9 | 2017 |
