Chemoenzymatic asymmetric synthesis of fluoxetine, atomoxetine, nisoxetine, and duloxetine RK Rej, T Das, S Hazra, S Nanda Tetrahedron: Asymmetry 24 (15-16), 913-918, 2013 | 46 | 2013 |
Targeting the estrogen receptor for the treatment of breast cancer: recent advances and challenges RK Rej, JE Thomas, RK Acharyya, JM Rae, S Wang Journal of Medicinal Chemistry 66 (13), 8339-8381, 2023 | 30 | 2023 |
EEDi-5285: an exceptionally potent, efficacious, and orally active small-molecule inhibitor of embryonic ectoderm development RK Rej, C Wang, J Lu, M Wang, E Petrunak, KP Zawacki, D McEachern, ... Journal of medicinal chemistry 63 (13), 7252-7267, 2020 | 27 | 2020 |
Stereoselective synthesis of a novel natural carbasugar and analogues from hydroxymethylated cycloalkenone scaffolds R Rej, N Jana, S Kar, S Nanda Tetrahedron: Asymmetry 23 (5), 364-372, 2012 | 21 | 2012 |
Asymmetric synthesis of naturally occurring nonenolide xyolide through cross metathesis and macrolactonization reaction RK Rej, A Jana, S Nanda Tetrahedron 70 (16), 2634-2642, 2014 | 20 | 2014 |
Asymmetric synthesis of dihydroartemisinic acid through intramolecular Stetter reaction RK Rej, RK Acharyya, S Nanda Tetrahedron 72 (32), 4931-4937, 2016 | 19 | 2016 |
Chemoenzymatic Asymmetric Total Synthesis of Nonanolide (Z)‐Cytospolides D, E and Their Stereoisomers RK Rej, S Nanda European Journal of Organic Chemistry 2014 (4), 860-871, 2014 | 18 | 2014 |
Exploration of Ring Rearrangement Metathesis Reaction: A General and Flexible Approach for the Rapid Construction [5,n]-Fused Bicyclic Systems en Route to … RK Acharyya, RK Rej, S Nanda The Journal of organic chemistry 83 (4), 2087-2103, 2018 | 17 | 2018 |
Discovery of EEDi-5273 as an exceptionally potent and orally efficacious EED inhibitor capable of achieving complete and persistent tumor regression RK Rej, C Wang, J Lu, M Wang, E Petrunak, KP Zawacki, D McEachern, ... Journal of medicinal chemistry 64 (19), 14540-14556, 2021 | 15 | 2021 |
Asymmetric synthesis of cytospolides C and D through successful exploration of stereoselective Julia–Kocienski olefination and Suzuki reaction followed by macrolactonization RK Rej, R Kumar, S Nanda Tetrahedron 71 (21), 3185-3194, 2015 | 14 | 2015 |
Discovery of ERD-3111 as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader with Strong Antitumor Activity Z Chen, B Hu, RK Rej, D Wu, RK Acharyya, M Wang, T Xu, J Lu, ... Journal of Medicinal Chemistry 66 (17), 12559-12585, 2023 | 13 | 2023 |
Asymmetric total synthesis of (−)-mangiferaelactone by using an appropriately substituted thiophene as a masked synthon for C-alkyl glycoside R Kumar, RK Rej, S Nanda Tetrahedron: Asymmetry 26 (14), 751-759, 2015 | 12 | 2015 |
A Metathetic Approach to [5/5/6] Aza-Tricyclic Core of Dendrobine, Kopsanone, and Lycopalhine A Type of Alkaloids S Kotha, S Pulletikurti Synthesis 51 (21), 3981-3988, 2019 | 10 | 2019 |
Therapies for the treatment of advanced/metastatic estrogen receptor-positive breast cancer: current situation and future directions RK Rej, J Roy, SR Allu Cancers 16 (3), 552, 2024 | 6 | 2024 |
Enantiopure hydroxymethylated cycloalkenols as privileged small molecular multifunctional scaffolds for the asymmetric synthesis of carbocycles R Kumar, RK Rej, J Halder, H Mandal, S Nanda Tetrahedron: Asymmetry 27 (11-12), 498-512, 2016 | 6 | 2016 |
Asymmetric synthesis of naturally occurring (−)-seimatopolides A and B RK Rej, P Pal, S Nanda Tetrahedron 70 (30), 4457-4470, 2014 | 6 | 2014 |
Preparation of imidazopyrimidines as EED inhibitors and the use thereof S Wang, R Rej, C Wang, M Wang, J Lu, CY Yang, E Fernandez-Salas, ... US Patent WO2,021,011,713, 2021 | 3 | 2021 |
Structure-based discovery of a highly potent and orally active small-molecule inhibitor of embryonic ectoderm development (EED) capable of achieving complete tumor regression RK Rej, C Wang, J Lu, M Wang, C Wang, EF Salas, J Stuckey, E Petrunak, ... ACS National Meeting & Exposition, Philadelphia, 2020 | 1 | 2020 |
Mdm2 protein degraders S Wang, Y Li, J Yang, A Aguilar, B Zhou, J Hu, F Xu, R Rej, X Han US Patent 2,017,176,957, 2017 | 1* | 2017 |
Monofunctional intermediates for ligand-dependent target protein degradation S Wang, Y Li, A Aguilar, B Zhou, J Hu, F Xu, QIN Chong, Y Hu, W Xiang, ... US Patent WO 2,017,176,958, 2017 | 1 | 2017 |