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Rohan Kalyan Rej
Rohan Kalyan Rej
Research Investigator, University of Michigan
在 umich.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Chemoenzymatic asymmetric synthesis of fluoxetine, atomoxetine, nisoxetine, and duloxetine
RK Rej, T Das, S Hazra, S Nanda
Tetrahedron: Asymmetry 24 (15-16), 913-918, 2013
462013
Targeting the estrogen receptor for the treatment of breast cancer: recent advances and challenges
RK Rej, JE Thomas, RK Acharyya, JM Rae, S Wang
Journal of Medicinal Chemistry 66 (13), 8339-8381, 2023
302023
EEDi-5285: an exceptionally potent, efficacious, and orally active small-molecule inhibitor of embryonic ectoderm development
RK Rej, C Wang, J Lu, M Wang, E Petrunak, KP Zawacki, D McEachern, ...
Journal of medicinal chemistry 63 (13), 7252-7267, 2020
272020
Stereoselective synthesis of a novel natural carbasugar and analogues from hydroxymethylated cycloalkenone scaffolds
R Rej, N Jana, S Kar, S Nanda
Tetrahedron: Asymmetry 23 (5), 364-372, 2012
212012
Asymmetric synthesis of naturally occurring nonenolide xyolide through cross metathesis and macrolactonization reaction
RK Rej, A Jana, S Nanda
Tetrahedron 70 (16), 2634-2642, 2014
202014
Asymmetric synthesis of dihydroartemisinic acid through intramolecular Stetter reaction
RK Rej, RK Acharyya, S Nanda
Tetrahedron 72 (32), 4931-4937, 2016
192016
Chemoenzymatic Asymmetric Total Synthesis of Nonanolide (Z)‐Cytospolides D, E and Their Stereoisomers
RK Rej, S Nanda
European Journal of Organic Chemistry 2014 (4), 860-871, 2014
182014
Exploration of Ring Rearrangement Metathesis Reaction: A General and Flexible Approach for the Rapid Construction [5,n]-Fused Bicyclic Systems en Route to …
RK Acharyya, RK Rej, S Nanda
The Journal of organic chemistry 83 (4), 2087-2103, 2018
172018
Discovery of EEDi-5273 as an exceptionally potent and orally efficacious EED inhibitor capable of achieving complete and persistent tumor regression
RK Rej, C Wang, J Lu, M Wang, E Petrunak, KP Zawacki, D McEachern, ...
Journal of medicinal chemistry 64 (19), 14540-14556, 2021
152021
Asymmetric synthesis of cytospolides C and D through successful exploration of stereoselective Julia–Kocienski olefination and Suzuki reaction followed by macrolactonization
RK Rej, R Kumar, S Nanda
Tetrahedron 71 (21), 3185-3194, 2015
142015
Discovery of ERD-3111 as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader with Strong Antitumor Activity
Z Chen, B Hu, RK Rej, D Wu, RK Acharyya, M Wang, T Xu, J Lu, ...
Journal of Medicinal Chemistry 66 (17), 12559-12585, 2023
132023
Asymmetric total synthesis of (−)-mangiferaelactone by using an appropriately substituted thiophene as a masked synthon for C-alkyl glycoside
R Kumar, RK Rej, S Nanda
Tetrahedron: Asymmetry 26 (14), 751-759, 2015
122015
A Metathetic Approach to [5/5/6] Aza-Tricyclic Core of Dendrobine, Kopsanone, and Lycopalhine A Type of Alkaloids
S Kotha, S Pulletikurti
Synthesis 51 (21), 3981-3988, 2019
102019
Therapies for the treatment of advanced/metastatic estrogen receptor-positive breast cancer: current situation and future directions
RK Rej, J Roy, SR Allu
Cancers 16 (3), 552, 2024
62024
Enantiopure hydroxymethylated cycloalkenols as privileged small molecular multifunctional scaffolds for the asymmetric synthesis of carbocycles
R Kumar, RK Rej, J Halder, H Mandal, S Nanda
Tetrahedron: Asymmetry 27 (11-12), 498-512, 2016
62016
Asymmetric synthesis of naturally occurring (−)-seimatopolides A and B
RK Rej, P Pal, S Nanda
Tetrahedron 70 (30), 4457-4470, 2014
62014
Preparation of imidazopyrimidines as EED inhibitors and the use thereof
S Wang, R Rej, C Wang, M Wang, J Lu, CY Yang, E Fernandez-Salas, ...
US Patent WO2,021,011,713, 2021
32021
Structure-​based discovery of a highly potent and orally active small-​molecule inhibitor of embryonic ectoderm development (EED) capable of achieving complete tumor regression
RK Rej, C Wang, J Lu, M Wang, C Wang, EF Salas, J Stuckey, E Petrunak, ...
ACS National Meeting & Exposition, Philadelphia, 2020
12020
Mdm2 protein degraders
S Wang, Y Li, J Yang, A Aguilar, B Zhou, J Hu, F Xu, R Rej, X Han
US Patent 2,017,176,957, 2017
1*2017
Monofunctional intermediates for ligand-dependent target protein degradation
S Wang, Y Li, A Aguilar, B Zhou, J Hu, F Xu, QIN Chong, Y Hu, W Xiang, ...
US Patent WO 2,017,176,958, 2017
12017
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