Surfing the p53 network B Vogelstein, D Lane, AJ Levine Nature 408 (6810), 307-310, 2000 | 9156 | 2000 |
p53, guardian of the genome. DP Lane Nature 358 (6381), 1992 | 7796 | 1992 |
T antigen is bound to a host protein in SY40-transformed cells DP Lane, LV Crawford Nature 278 (5701), 261-263, 1979 | 3900 | 1979 |
p53 in health and disease KH Vousden, DP Lane Nature reviews Molecular cell biology 8 (4), 275-283, 2007 | 2824 | 2007 |
Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections: An index of cell proliferation with evidence of deregulated expression in some, neoplasms PA Hall, DA Levison, AL Woods, CCW Yu, DB Kellock, JA Watkins, ... The Journal of pathology 162 (4), 285-294, 1990 | 2030 | 1990 |
Increased expression of mutant forms of p53 oncogene in primary lung cancer R Iggo, J Bartek, D Lane, K Gatter, AL Harris The Lancet 335 (8691), 675-679, 1990 | 1364 | 1990 |
p53 mutations in colorectal cancer. NR Rodrigues, A Rowan, ME Smith, IB Kerr, WF Bodmer, JV Gannon, ... Proceedings of the National Academy of Sciences 87 (19), 7555-7559, 1990 | 1340 | 1990 |
Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form. JV Gannon, R Greaves, R Iggo, DP Lane The EMBO journal 9 (5), 1595-1602, 1990 | 1305 | 1990 |
Regulation of the specific DNA binding function of p53 TR Hupp, DW Meek, CA Midgley, DP Lane Cell 71 (5), 875-886, 1992 | 1304 | 1992 |
p53: oncogene or anti-oncogene DP Lane, S Benchimol Genes Dev 4 (1), 1-8, 1990 | 1173 | 1990 |
Awakening guardian angels: drugging the p53 pathway CJ Brown, S Lain, CS Verma, AR Fersht, DP Lane Nature Reviews Cancer 9 (12), 862-873, 2009 | 1121 | 2009 |
p53 isoforms can regulate p53 transcriptional activity JC Bourdon, K Fernandes, F Murray-Zmijewski, G Liu, A Diot, ... Genes & development 19 (18), 2122-2137, 2005 | 1085 | 2005 |
Differential induction of transcriptionally active p53 following UV or lonizing radiation: Defects in chromosome instability syndromes? X Lu, DP Lane Cell 75 (4), 765-778, 1993 | 1052 | 1993 |
A laboratory manual ED Harlow, D Lane New York: Cold Spring Harbor Laboratory 579, 44, 1988 | 966* | 1988 |
Antibody fragments from a ‘single pot’phage display library as immunochemical reagents. A Nissim, HR Hoogenboom, IM Tomlinson, G Flynn, C Midgley, D Lane, ... The EMBO journal 13 (3), 692-698, 1994 | 932 | 1994 |
Monoclonal antibody analysis of the proliferating cell nuclear antigen (PCNA) Structural conservation and the detection of a nucleolar form NH Waseem, DP Lane Journal of Cell Science 96 (1), 121-129, 1990 | 906 | 1990 |
Drugging the p53 pathway: understanding the route to clinical efficacy KH Khoo, CS Verma, DP Lane Nature reviews Drug discovery 13 (3), 217-236, 2014 | 881 | 2014 |
High levels of p53 protein in UV-irradiated normal human skin. PA Hall, PH McKee, HD Menage, R Dover, DP Lane Oncogene 8 (1), 203-207, 1993 | 880 | 1993 |
SUMO‐1 modification activates the transcriptional response of p53 MS Rodriguez, JMP Desterro, S Lain, CA Midgley, DP Lane, RT Hay The EMBO journal, 1999 | 843 | 1999 |
Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines. J Bartek, R Iggo, J Gannon, DP Lane Oncogene 5 (6), 893-899, 1990 | 810 | 1990 |