An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing JC Tanny, GJ Dowd, J Huang, H Hilz, D Moazed Cell 99 (7), 735-745, 1999 | 517 | 1999 |
Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs SD Taverna, S Ilin, RS Rogers, JC Tanny, H Lavender, H Li, L Baker, ... Molecular cell 24 (5), 785-796, 2006 | 399 | 2006 |
Steps in assembly of silent chromatin in yeast: Sir3-independent binding of a Sir2/Sir4 complex to silencers and role for Sir2-dependent deacetylation GJ Hoppe, JC Tanny, AD Rudner, SA Gerber, S Danaie, SP Gygi, ... Molecular and cellular biology 22 (12), 4167-4180, 2002 | 382 | 2002 |
Coupling of histone deacetylation to NAD breakdown by the yeast silencing protein Sir2: Evidence for acetyl transfer from substrate to an NAD breakdown product JC Tanny, D Moazed Proceedings of the National Academy of Sciences 98 (2), 415-420, 2001 | 367 | 2001 |
Assembly of the SIR complex and its regulation by O-acetyl-ADP-ribose, a product of NAD-dependent histone deacetylation GG Liou, JC Tanny, RG Kruger, T Walz, D Moazed Cell 121 (4), 515-527, 2005 | 330 | 2005 |
Histone chaperone Asf1 is required for histone H3 lysine 56 acetylation, a modification associated with S phase in mitosis and meiosis J Recht, T Tsubota, JC Tanny, RL Diaz, JM Berger, X Zhang, BA Garcia, ... Proceedings of the National Academy of Sciences 103 (18), 6988-6993, 2006 | 302 | 2006 |
Ubiquitylation of histone H2B controls RNA polymerase II transcription elongation independently of histone H3 methylation JC Tanny, H Erdjument-Bromage, P Tempst, CD Allis Genes & development 21 (7), 835-847, 2007 | 177 | 2007 |
A Cdk9–PP1 switch regulates the elongation–termination transition of RNA polymerase II PK Parua, GT Booth, M Sansó, B Benjamin, JC Tanny, JT Lis, RP Fisher Nature 558 (7710), 460-464, 2018 | 153 | 2018 |
Components of the ESCRT pathway, DFG16, and YGR122w are required for Rim101 to act as a corepressor with Nrg1 at the negative regulatory element of the DIT1 gene of … K Rothfels, JC Tanny, E Molnar, H Friesen, C Commisso, J Segall Molecular and cellular biology 25 (15), 6772-6788, 2005 | 101 | 2005 |
Budding yeast silencing complexes and regulation of Sir2 activity by protein-protein interactions JC Tanny, DS Kirkpatrick, SA Gerber, SP Gygi, D Moazed Molecular and cellular biology 24 (16), 6931-6946, 2004 | 88 | 2004 |
Structure of the coiled-coil dimerization motif of Sir4 and its interaction with Sir3 JF Chang, BE Hall, JC Tanny, D Moazed, D Filman, T Ellenberger Structure 11 (6), 637-649, 2003 | 80 | 2003 |
A positive feedback loop links opposing functions of P-TEFb/Cdk9 and histone H2B ubiquitylation to regulate transcript elongation in fission yeast M Sansó, KM Lee, L Viladevall, PÉ Jacques, V Pagé, S Nagy, A Racine, ... PLoS genetics 8 (8), e1002822, 2012 | 63 | 2012 |
A model for step‐wise assembly of heterochromatin in yeast D Moazed, AD Rudner, J Huang, GJ Hoppe, JC Tanny Reversible Protein Acetylation: Novartis Foundation Symposium 259 259, 48-62, 2004 | 63 | 2004 |
The PAF complex and Prf1/Rtf1 delineate distinct Cdk9-dependent pathways regulating transcription elongation in fission yeast J Mbogning, S Nagy, V Page, B Schwer, S Shuman, RP Fisher, JC Tanny PLoS genetics 9 (12), e1004029, 2013 | 60 | 2013 |
A nucleosome turnover map reveals that the stability of histone H4 Lys20 methylation depends on histone recycling in transcribed chromatin JP Svensson, M Shukla, V Menendez-Benito, U Norman-Axelsson, ... Genome research 25 (6), 872-883, 2015 | 59 | 2015 |
Therapeutic targeting of the general RNA polymerase II transcription machinery RD Martin, TE Hébert, JC Tanny International Journal of Molecular Sciences 21 (9), 3354, 2020 | 47 | 2020 |
Chromatin modification by the RNA Polymerase II elongation complex JC Tanny Transcription 5 (5), e988093, 2014 | 44 | 2014 |
Signal profiling of the β1AR reveals coupling to novel signalling pathways and distinct phenotypic responses mediated by β1AR and β2AR V Lukasheva, D Devost, C Le Gouill, Y Namkung, RD Martin, JM Longpré, ... Scientific reports 10 (1), 8779, 2020 | 31 | 2020 |
Dopamine D1 receptor signalling in dyskinetic Parkinsonian rats revealed by fiber photometry using FRET-based biosensors J Jones-Tabah, H Mohammad, S Hadj-Youssef, LEH Kim, RD Martin, ... Scientific Reports 10 (1), 14426, 2020 | 27 | 2020 |
Cdk9 and H2Bub1 signal to Clr6-CII/Rpd3S to suppress aberrant antisense transcription M Sansó, PK Parua, D Pinto, JP Svensson, V Pagé, DA Bitton, ... Nucleic acids research 48 (13), 7154-7168, 2020 | 25 | 2020 |