RNA/DNA hybrid interactome identifies DXH9 as a molecular player in transcriptional termination and R-loop-associated DNA damage A Cristini, M Groh, MS Kristiansen, N Gromak Cell reports 23 (6), 1891-1905, 2018 | 367 | 2018 |
N6-methyladenosine regulates the stability of RNA:DNA hybrids in human cells A Abakir, TC Giles, A Cristini, JM Foster, N Dai, M Starczak, ... Nature genetics 52 (1), 48-55, 2020 | 186 | 2020 |
Dual processing of R-loops and topoisomerase I induces transcription-dependent DNA double-strand breaks A Cristini, G Ricci, S Britton, S Salimbeni, SN Huang, J Marinello, ... Cell reports 28 (12), 3167-3181. e6, 2019 | 140 | 2019 |
Senataxin: genome guardian at the interface of transcription and neurodegeneration M Groh, LO Albulescu, A Cristini, N Gromak Journal of molecular biology 429 (21), 3181-3195, 2017 | 138 | 2017 |
DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions A Cristini, JH Park, G Capranico, G Legube, G Favre, O Sordet Nucleic acids research 44 (3), 1161-1178, 2016 | 57 | 2016 |
Dynamic effects of topoisomerase I inhibition on R-loops and short transcripts at active promoters J Marinello, S Bertoncini, I Aloisi, A Cristini, G Malagoli Tagliazucchi, ... PLoS One 11 (1), e0147053, 2016 | 53 | 2016 |
RNase H2, mutated in Aicardi‐Goutières syndrome, resolves co-transcriptional R-loops to prevent DNA breaks and inflammation A Cristini, M Tellier, F Constantinescu, C Accalai, LO Albulescu, ... Nature communications 13 (1), 2961, 2022 | 49 | 2022 |
RhoB promotes γH2AX dephosphorylation and DNA double-strand break repair K Mamouni, A Cristini, J Guirouilh-Barbat, S Monferran, A Lemarié, ... Molecular and cellular biology 34 (16), 3144-3155, 2014 | 49 | 2014 |
RhoB promotes cancer initiation by protecting keratinocytes from UVB-induced apoptosis but limits tumor aggressiveness N Meyer, A Peyret-Lacombe, B Canguilhem, C Médale-Giamarchi, ... Journal of Investigative Dermatology 134 (1), 203-212, 2014 | 33 | 2014 |
APOBEC3B regulates R-loops and promotes transcription-associated mutagenesis in cancer JL McCann, A Cristini, EK Law, SY Lee, M Tellier, MA Carpenter, C Beghè, ... Nature Genetics 55 (10), 1721-1734, 2023 | 17 | 2023 |
PARP-1-dependent RND1 transcription induced by topoisomerase I cleavage complexes confers cellular resistance to camptothecin L Mouly, K Mamouni, R Gence, A Cristini, J Cherier, A Castinel, ... Cell Death & Disease 9 (9), 931, 2018 | 10 | 2018 |
Transcription-dependent DNA double-strand breaks and human disease A Cristini, N Gromak, O Sordet Molecular & Cellular Oncology 7 (2), 1691905, 2020 | 9 | 2020 |
R-loop homeostasis and cancer mutagenesis promoted by the DNA cytosine deaminase APOBEC3B JL McCann, A Cristini, EK Law, SY Lee, M Tellier, MA Carpenter, C Beghè, ... BioRxiv, 2021.08. 30.458235, 2021 | 8 | 2021 |
Transcription-associated DNA breaks and cancer: A matter of DNA topology A Cristini, M Géraud, O Sordet International Review of Cell and Molecular Biology 364, 195-240, 2021 | 7 | 2021 |
TDP1 mutation causing SCAN1 neurodegenerative syndrome hampers the repair of transcriptional DNA double-strand breaks M Geraud, A Cristini, S Salimbeni, N Bery, V Jouffret, M Russo, AC Ajello, ... Cell Reports 43 (5), 2024 | | 2024 |
DNA double-strand break formation and signalling in response to transcription-blocking topoisomerase I complexes| Theses. fr A Cristini Toulouse 3, 2015 | | 2015 |
DNA double-strand break formation and signalling in response to transcription-blocking topoisomerase I complexes A Cristini Université Paul Sabatier-Toulouse III, 2015 | | 2015 |
Dual Processing of R-Loops and Topoisomerase I Induces Transcription-Dependent DNA Double-Strand Breaks FEN generates SSB, A Cristini, G Ricci, S Britton, G Capranico, N Gromak, ... | | |