Response to ERBB3-Directed Targeted Therapy in NRG1-Rearranged Cancers A Drilon, R Somwar, BP Mangatt, H Edgren, P Desmeules, A Ruusulehto, ... Cancer discovery 8 (6), 686-695, 2018 | 189 | 2018 |
Activation of KRAS mediates resistance to targeted therapy in MET exon 14–mutant non–small cell lung cancer K Suzawa, M Offin, D Lu, C Kurzatkowski, M Vojnic, RS Smith, JK Sabari, ... Clinical Cancer Research 25 (4), 1248-1260, 2019 | 123 | 2019 |
Zenocutuzumab, a HER2xHER3 Bispecific Antibody, Is Effective Therapy for Tumors Driven by NRG1 Gene Rearrangements AM Schram, I Odintsov, M Espinosa-Cotton, I Khodos, WJ Sisso, ... Cancer Discovery 12 (5), 1233-1247, 2022 | 115 | 2022 |
Overcoming MET-dependent resistance to selective RET inhibition in patients with RET fusion–positive lung cancer by combining selpercatinib with crizotinib EY Rosen, ML Johnson, SE Clifford, R Somwar, JF Kherani, J Son, ... Clinical Cancer Research 27 (1), 34-42, 2021 | 114 | 2021 |
Acquired BRAF rearrangements induce secondary resistance to EGFR therapy in EGFR-mutated lung cancers M Vojnic, D Kubota, C Kurzatkowski, M Offin, K Suzawa, R Benayed, ... Journal of Thoracic Oncology 14 (5), 802-815, 2019 | 92 | 2019 |
NTRK kinase domain mutations in cancer variably impact sensitivity to type I and type II inhibitors R Somwar, NE Hofmann, B Smith, I Odintsov, M Vojnic, I Linkov, A Tam, ... Communications biology 3 (1), 776, 2020 | 52 | 2020 |
The Anti-HER3 mAb Seribantumab Effectively Inhibits Growth of Patient-Derived and Isogenic Cell Line and Xenograft Models with Oncogenic NRG1 Fusions I Odintsov, AJW Lui, WJ Sisso, E Gladstone, Z Liu, L Delasos, RI Kurth, ... Clinical Cancer Research 27 (11), 3154-3166, 2021 | 42 | 2021 |
Response to ERBB3-directed targeted therapy in NRG1-rearranged cancers. Cancer Discov. 2018; 8: 686–695. doi: 10.1158/2159-8290 A Drilon, R Somwar, BP Mangatt, H Edgren, P Desmeules, A Ruusulehto, ... CD-17-1004.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 33 | |
Novel patient-derived models of desmoplastic small round cell tumor confirm a targetable dependency on ERBB signaling RS Smith, I Odintsov, Z Liu, AJW Lui, T Hayashi, M Vojnic, Y Suehara, ... Disease Models & Mechanisms 15 (1), dmm047621, 2022 | 20 | 2022 |
Zenocutuzumab, a HER2xHER3 bispecific antibody, is effective therapy for tumors driven by NRG1 gene rearrangements. Cancer Discov. 2022; 12: 1233–47 AM Schram, I Odintsov, M Espinosa-Cotton, I Khodos, WJ Sisso, ... CD-21-1119, 0 | 18 | |
Intrathecal therapy for the management of leptomeningeal metastatic disease: a scoping review of the current literature and ongoing clinical trials P Palmisciano, G Watanabe, A Conching, C Ogasawara, M Vojnic, ... Journal of Neuro-Oncology 160 (1), 79-100, 2022 | 15 | 2022 |
Vepafestinib is a pharmacologically advanced RET-selective inhibitor with high CNS penetration and inhibitory activity against RET solvent front mutations I Miyazaki, I Odintsov, K Ishida, AJW Lui, M Kato, T Suzuki, T Zhang, ... Nature Cancer 4 (9), 1345-1361, 2023 | 14 | 2023 |
Comparison of TAS0953/HM06 and selpercatinib in RET fusion-driven preclinical disease models of intracranial metastases I Odintsov, AJW Lui, K Ishizawa, I Miyazaki, I Khodos, K Wakayama, ... J. Clin. Oncol 40, 2024, 2022 | 13 | 2022 |
RET inhibition in novel patient-derived models of RET fusion-positive lung adenocarcinoma reveals a role for MYC upregulation T Hayashi, I Odintsov, RS Smith, K Ishizawa, AJW Liu, L Delasos, ... Disease Models & Mechanisms 14 (2), dmm047779, 2021 | 13 | 2021 |
Abstract P233: TAS0953/HM06 is effective in preclinical models of diverse tumor types driven by RET alterations I Odintsov, RI Kurth, K Ishizawa, L Delasos, AJW Lui, I Khodos, CJ Hagen, ... Molecular Cancer Therapeutics 20 (12_Supplement), P233-P233, 2021 | 11 | 2021 |
The abscopal effect: inducing immunogenicity in the treatment of brain metastases secondary to lung cancer and melanoma JA Tracz, BM Donnelly, S Ngu, M Vojnic, AG Wernicke, RS D’Amico Journal of Neuro-Oncology 163 (1), 1-14, 2023 | 8 | 2023 |
Intraoperative awake language mapping correlates to preoperative connectomics imaging: An instructive case HA Shah, F Ablyazova, A Alrez, AG Wernicke, M Vojnic, JW Silverstein, ... Clinical Neurology and Neurosurgery 229, 107751, 2023 | 5 | 2023 |
Brain metastasis screening in the molecular age JK Tabor, A Onoichenco, V Narayan, AG Wernicke, RS D’Amico, M Vojnic Neuro-Oncology Advances 5 (1), vdad080, 2023 | 5 | 2023 |
Establishment of multiple novel patient-derived models of desmoplastic small round cell tumor enabling functional characterization of ERBB pathway signaling and pre-clinical … RS Smith, I Odintsov, Z Liu, AJW Lui, T Hayashi, M Vojnic, Y Suehara, ... bioRxiv, 2020.09. 22.308940, 2020 | 3 | 2020 |
A 33-Year-Old Man With Chest Pain M Ballenberger, M Vojnic, M Indaram, S Machnicki, M Harshan, ... Chest 161 (1), e43-e49, 2022 | 2 | 2022 |