Role of STAT3 signaling transduction pathways in cancer stem cell-associated chemoresistance PC Shih, KC Mei Drug Discovery Today 26 (6), 1450-1458, 2021 | 41 | 2021 |
Revisiting the development of small molecular inhibitors that directly target the signal transducer and activator of transcription 3 (STAT3) domains PC Shih Life sciences 242, 117241, 2020 | 34 | 2020 |
Pardaxin Activates Excessive Mitophagy and Mitochondria-Mediated Apoptosis in Human Ovarian Cancer by Inducing Reactive Oxygen Species YP Chen, PC Shih, CW Feng, CC Wu, KH Tsui, YH Lin, HM Kuo, ZH Wen Antioxidants 10 (12), 1883, 2021 | 24 | 2021 |
The role of the STAT3 signaling transduction pathways in radioresistance PC Shih Pharmacology & Therapeutics, 108118, 2022 | 22 | 2022 |
Sinularin, an Anti-Cancer Agent Causing Mitochondria-Modulated Apoptosis and Cytoskeleton Disruption in Human Hepatocellular Carcinoma CY Ko, PC Shih, PW Huang, YH Lee, YF Chen, MH Tai, CH Liu, ZH Wen, ... International Journal of Molecular Sciences 22 (8), 3946, 2021 | 19 | 2021 |
The antimicrobial peptide tilapia piscidin 3 induces mitochondria-modulated intrinsic apoptosis of osteosarcoma cells CH Yuan, YL Ma, PC Shih, CT Chen, SY Cheng, CY Pan, YH Jean, ... Biochemical Pharmacology 178, 114064, 2020 | 16 | 2020 |
TP3, an antimicrobial peptide, inhibits infiltration and motility of glioblastoma cells via modulating the tumor microenvironment YF Chen, PC Shih, HM Kuo, SN Yang, YY Lin, WF Chen, SJ Tzou, HT Liu, ... Cancer medicine 9 (11), 3918-3931, 2020 | 14 | 2020 |
Isoaaptamine increases ROS levels causing autophagy and mitochondria-mediated apoptosis in glioblastoma multiforme cells ZH Wen, HM Kuo, PC Shih, LC Hsu, JMJ Chuang, NF Chen, HW Sun, ... Biomedicine & Pharmacotherapy 160, 114359, 2023 | 13 | 2023 |
Sinularin Induces Oxidative Stress-Mediated Apoptosis and Mitochondrial Dysfunction, and Inhibits Angiogenesis in Glioblastoma Cells SY Hsu, ZH Wen, PC Shih, HM Kuo, SC Lin, HT Liu, YH Lee, YJ Wang, ... Antioxidants 11 (8), 1433, 2022 | 13 | 2022 |
A high-throughput fluorescence polarization assay for discovering inhibitors targeting the DNA-binding domain of signal transducer and activator of transcription 3 (STAT3) PC Shih, Y Yang, GN Parkinson, A Wilderspin, G Wells Oncotarget 9 (66), 32690, 2018 | 13 | 2018 |
Stellettin B-Induced Oral Cancer Cell Death via Endoplasmic Reticulum Stress–Mitochondrial Apoptotic and Autophagic Signaling Pathway TJ Kuo, YH Jean, PC Shih, SY Cheng, HM Kuo, YT Lee, YC Lai, ... International Journal of Molecular Sciences 23 (15), 8813, 2022 | 8 | 2022 |
Development of Ultrapure and Potent Tannic Acids as a Pan-coronal Antiviral Therapeutic PC Shih, YW Mao, JW Hu, HY Hsieh, TM Shih, LP Lu, WH Chang, ... ACS Pharmacology & Translational Science 5 (6), 400-412, 2022 | 8 | 2022 |
Current Status of Oligonucleotide-Based Protein Degraders PC Shih, M Naganuma, Y Demizu, M Naito Pharmaceutics 15 (3), 765, 2023 | 6 | 2023 |
Development of decoy oligonucleotide-warheaded chimeric molecules targeting STAT3 PC Shih, M Naganuma, G Tsuji, Y Demizu, M Naito Bioorganic & Medicinal Chemistry 95, 117507, 2023 | 5 | 2023 |
Ultrapure and potent tannic acid (UPPTA) is a novel inhibitor of D-amino acid oxidase to improve the N-methyl-D-aspartate function of CNS disorders YW Mao, LP Lu, PC Shih, JF Hsiao, V Wu, GE Tsai Phytomedicine Plus 3 (1), 100399, 2023 | 3 | 2023 |
The anti-angiogenic and anti-vasculogenic mimicry effects of GN25 in endothelial and glioma cells ZH Wen, L Chang, SN Yang, CL Yu, FY Tung, HM Kuo, IC Lu, CY Wu, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1871 (7), 119799, 2024 | | 2024 |
STAT3 phosphorylation inhibitor Bt354 exhibits anti‐neoplastic activity in glioblastoma multiforme cells YC Chiang, P Selvam, YX Liu, PC Shih, NF Chen, HM Kuo, HYH Lin, ... Environmental Toxicology 39 (6), 3292-3303, 2024 | | 2024 |
Perspective Chapter-NMDA Treatments for CNS Disorders CH Lin, PC Shih, GE Tsai IntechOpen, 2021 | | 2021 |