Modeling of TREX1-dependent autoimmune disease using human stem cells highlights L1 accumulation as a source of neuroinflammation CA Thomas, L Tejwani, CA Trujillo, PD Negraes, RH Herai, P Mesci, ... Cell Stem Cell 21 (3), 319-331. e8, 2017 | 293 | 2017 |
Cortical organoids model early brain development disrupted by 16p11. 2 copy number variants in autism J Urresti, P Zhang, P Moran-Losada, NK Yu, PD Negraes, CA Trujillo, ... Molecular psychiatry 26 (12), 7560-7580, 2021 | 92* | 2021 |
Blocking Zika virus vertical transmission P Mesci, A Macia, SM Moore, SA Shiryaev, A Pinto, CT Huang, L Tejwani, ... Scientific Reports 8 (1), 1-13, 2018 | 79 | 2018 |
Pharmacological reversal of synaptic and network pathology in human MECP2‐KO neurons and cortical organoids CA Trujillo, JW Adams, PD Negraes, C Carromeu, L Tejwani, A Acab, ... EMBO Molecular Medicine 13 (1), e12523, 2021 | 66 | 2021 |
Modeling neuro-immune interactions during Zika virus infection P Mesci, A Macia, CN LaRock, L Tejwani, IR Fernandes, NA Suarez, ... Human Molecular Genetics 27 (1), 41-52, 2018 | 59 | 2018 |
Pathogenic mechanisms underlying spinocerebellar ataxia type 1 L Tejwani, J Lim Cellular and Molecular Life Sciences 77 (20), 4015-4029, 2020 | 25 | 2020 |
Association of CACNA1C with bipolar disorder among the Pakistani population M Khalid, TM Driessen, JS Lee, L Tejwani, A Rasool, M Saqlain, PA Shiaq, ... Gene 664, 119-126, 2018 | 22 | 2018 |
Genetic risk of autism spectrum disorder in a Pakistani population M Khalid, H Raza, T M. Driessen, P J. Lee, L Tejwani, A Sami, M Nawaz, ... Genes 11 (10), 1206, 2020 | 20 | 2020 |
Differential effects of Wnt-β-catenin signaling in Purkinje cells and Bergmann glia in spinocerebellar ataxia type 1 K Luttik, L Tejwani, H Ju, T Driessen, CJLM Smeets, CR Edamakanti, ... Proceedings of the National Academy of Sciences 119 (34), e2208513119, 2022 | 10* | 2022 |
Microglia regulate brain progranulin levels through the endocytosis/lysosomal pathway T Dong, L Tejwani, Y Jung, H Kokubu, K Luttik, TM Driessen, J Lim JCI insight 6 (22), 2021 | 8 | 2021 |
Longitudinal single-cell transcriptional dynamics throughout neurodegeneration in SCA1 L Tejwani, NG Ravindra, C Lee, Y Cheng, B Nguyen, K Luttik, L Ni, ... Neuron, 2021.10. 22.465444, 2023 | 7 | 2023 |
Activity of retrotransposons in stem cells and differentiated cells A Macia, L Tejwani, P Mesci, A Muotri, JL Garcia-Perez Human Retrotransposons in Health and Disease, 127-156, 2017 | 5 | 2017 |
Reduction of nemo-like kinase increases lysosome biogenesis and ameliorates TDP-43–related neurodegeneration L Tejwani, Y Jung, H Kokubu, S Sowmithra, L Ni, C Lee, B Sanders, ... The Journal of Clinical Investigation 133 (16), 2023 | 4 | 2023 |
A Novel Missense Mutation in ERCC8 Co-Segregates with Cerebellar Ataxia in a Consanguineous Pakistani Family Z Gauhar, L Tejwani, U Abdullah, S Saeed, S Shafique, M Badshah, ... Cells 11 (19), 3090, 2022 | 1 | 2022 |
Lysosomal defects in Grn loss of function modulate microglial cell state and immune responses L Tejwani, G Di Paolo Alzheimer's Association International Conference, 2024 | | 2024 |
Exploring the role of protein quality control in aging and age-associated neurodegenerative diseases N Gogia, V Olmos, F Haidery, K Luttik, L Tejwani, J Lim Anti-Aging Drug Discovery on the Basis of Hallmarks of Aging, 139-171, 2022 | | 2022 |
Uncovering novel roles for glia in neurodegenerative diseases LL Tejwani | | 2021 |
Association of CACNA1C with Bipolar disorder among the Pakistani population. MK Madiha Khalid, TM Driessen, LJS Lee JongSeo, L Tejwani, ... | | 2018 |
Hunting for the mutant without the MAP (K) L Tejwani, J Lim Cell Research 27 (12), 1403-1404, 2017 | | 2017 |
Genome Editing in Stem Cells L Tejwani, CA Trujillo, CA Thomas, AR Muotri Working with Stem Cells, 287, 2016 | | 2016 |