The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria M Bosma, R Minnaard, LM Sparks, G Schaart, M Losen, MH De Baets, ... Histochemistry and cell biology 137, 205-216, 2012 | 193 | 2012 |
Perilipin 2 improves insulin sensitivity in skeletal muscle despite elevated intramuscular lipid levels M Bosma, MKC Hesselink, LM Sparks, S Timmers, MJ Ferraz, F Mattijssen, ... Diabetes 61 (11), 2679-2690, 2012 | 191 | 2012 |
Re-evaluating lipotoxic triggers in skeletal muscle: relating intramyocellular lipid metabolism to insulin sensitivity M Bosma, S Kersten, MKC Hesselink, P Schrauwen Progress in lipid research 51 (1), 36-49, 2012 | 169 | 2012 |
Overexpression of PLIN5 in skeletal muscle promotes oxidative gene expression and intramyocellular lipid content without compromising insulin sensitivity M Bosma, LM Sparks, GJ Hooiveld, JA Jorgensen, SM Houten, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2013 | 137 | 2013 |
Sequestration of fatty acids in triglycerides prevents endoplasmic reticulum stress in an in vitro model of cardiomyocyte lipotoxicity M Bosma, DH Dapito, Z Drosatos-Tampakaki, N Huiping-Son, LS Huang, ... Biochimica Et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2014 | 109 | 2014 |
Interleukin 34: a new modulator of human and experimental inflammatory bowel disease S Zwicker, GL Martinez, M Bosma, M Gerling, R Clark, M Majster, ... Clinical science 129 (3), 281-290, 2015 | 105 | 2015 |
Augmenting muscle diacylglycerol and triacylglycerol content by blocking fatty acid oxidation does not impede insulin sensitivity S Timmers, M Nabben, M Bosma, B Van Bree, E Lenaers, D Van Beurden, ... Proceedings of the National Academy of Sciences 109 (29), 11711-11716, 2012 | 102 | 2012 |
FNDC4 acts as an anti-inflammatory factor on macrophages and improves colitis in mice M Bosma, M Gerling, J Pasto, A Georgiadi, E Graham, O Shilkova, Y Iwata, ... Nature Communications 7 (1), 11314, 2016 | 82 | 2016 |
Lipid droplet dynamics in skeletal muscle M Bosma Experimental Cell Research 340 (2), 180-186, 2016 | 78 | 2016 |
Targeting of mitochondrial reactive oxygen species production does not avert lipid-induced insulin resistance in muscle tissue from mice S Paglialunga, B Van Bree, M Bosma, MP Valdecantos, ... Diabetologia 55, 2759-2768, 2012 | 53 | 2012 |
Decoration of intramyocellular lipid droplets with PLIN5 modulates fasting-induced insulin resistance and lipotoxicity in humans A Gemmink, M Bosma, HJH Kuijpers, J Hoeks, G Schaart, ... Diabetologia 59, 1040-1048, 2016 | 51 | 2016 |
Chemical imaging of lipid droplets in muscle tissues using hyperspectral coherent Raman microscopy N Billecke, G Rago, M Bosma, G Eijkel, A Gemmink, P Leproux, G Huss, ... Histochemistry and cell biology 141, 263-273, 2014 | 46 | 2014 |
Effects of Bezafibrate Treatment in a Patient and a Carrier With Mutations in the PNPLA2 Gene, Causing Neutral Lipid Storage Disease With Myopathy T van de Weijer, B Havekes, L Bilet, J Hoeks, L Sparks, M Bosma, ... Circulation Research 112 (5), e51-e54, 2013 | 46 | 2013 |
Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue A Georgiadi, V Lopez-Salazar, RE Merahbi, RA Karikari, X Ma, A Mourão, ... Nature communications 12 (1), 2999, 2021 | 35 | 2021 |
Expression analysis of Fibronectin Type III Domain‐Containing (FNDC) genes in inflammatory bowel disease and colorectal cancer T Wuensch, J Wizenty, J Quint, W Spitz, M Bosma, O Becker, A Adler, ... Gastroenterology research and practice 2019 (1), 3784172, 2019 | 35 | 2019 |
Perilipin 5 mediated lipid droplet remodelling revealed by coherent Raman imaging N Billecke, M Bosma, W Rock, F Fleissner, G Best, P Schrauwen, ... Integrative Biology 7 (4), 467-476, 2015 | 32 | 2015 |
ANT1-mediated fatty acid-induced uncoupling as a target for improving myocellular insulin sensitivity LM Sparks, A Gemmink, E Phielix, M Bosma, G Schaart, ... Diabetologia 59, 1030-1039, 2016 | 31 | 2016 |
Lipid homeostasis in exercise M Bosma Drug discovery today 19 (7), 1019-1023, 2014 | 31 | 2014 |
One-leg inactivity induces a reduction in mitochondrial oxidative capacity, intramyocellular lipid accumulation and reduced insulin signalling upon lipid infusion: a human … L Bilet, E Phielix, T van de Weijer, A Gemmink, M Bosma, ... Diabetologia 63, 1211-1222, 2020 | 29 | 2020 |
Reduced incorporation of fatty acids into triacylglycerol in myotubes from obese individuals with type 2 diabetes LM Sparks, M Bosma, B Brouwers, T van de Weijer, L Bilet, G Schaart, ... Diabetes 63 (5), 1583-1593, 2014 | 29 | 2014 |