Insights into GATA-1-mediated gene activation versus repression via genome-wide chromatin occupancy analysis M Yu, L Riva, H Xie, Y Schindler, TB Moran, Y Cheng, D Yu, R Hardison, ... Molecular cell 36 (4), 682-695, 2009 | 356 | 2009 |
Bridging high-throughput genetic and transcriptional data reveals cellular responses to alpha-synuclein toxicity E Yeger-Lotem, L Riva, LJ Su, AD Gitler, AG Cashikar, OD King, ... Nature genetics 41 (3), 316, 2009 | 335 | 2009 |
Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor SMA Islam, M Díaz-Gay, Y Wu, M Barnes, R Vangara, EN Bergstrom, ... Cell genomics 2 (11), 2022 | 177 | 2022 |
Silencer elements as possible inhibitors of pseudoexon splicing M Sironi, G Menozzi, L Riva, R Cagliani, GP Comi, N Bresolin, R Giorda, ... Nucleic acids research 32 (5), 1783-1791, 2004 | 171 | 2004 |
No unexpected CRISPR-Cas9 off-target activity revealed by trio sequencing of gene-edited mice V Iyer, K Boroviak, M Thomas, B Doe, L Riva, E Ryder, DJ Adams PLoS genetics 14 (7), e1007503, 2018 | 142 | 2018 |
In vivo functional platform targeting patient-derived xenografts identifies WDR5-Myc association as a critical determinant of pancreatic cancer A Carugo, G Genovese, S Seth, L Nezi, JL Rose, D Bossi, A Cicalese, ... Cell reports 16 (1), 133-147, 2016 | 135 | 2016 |
The mutational signature profile of known and suspected human carcinogens in mice L Riva, AR Pandiri, YR Li, A Droop, J Hewinson, MA Quail, V Iyer, ... Nature genetics 52 (11), 1189-1197, 2020 | 108 | 2020 |
INSPEcT: a computational tool to infer mRNA synthesis, processing and degradation dynamics from RNA-and 4sU-seq time course experiments S De Pretis, T Kress, MJ Morelli, GEM Melloni, L Riva, B Amati, ... Bioinformatics 31 (17), 2829-2835, 2015 | 73 | 2015 |
Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice Y Rose Li, KD Halliwill, CJ Adams, V Iyer, L Riva, R Mamunur, KY Jen, ... Nature communications 11 (1), 394, 2020 | 72 | 2020 |
In Vivo Genetic Screens of Patient-Derived Tumors Revealed Unexpected Frailty of the Transformed Phenotype D Bossi, A Cicalese, GI Dellino, L Luzi, L Riva, C D'Alesio, GR Diaferia, ... Cancer discovery 6 (6), 650-663, 2016 | 69 | 2016 |
A locus on 15q15-15qter influences dyslexia: further support from a transmission/disequilibrium study in an Italian speaking population C Marino, R Giorda, L Vanzin, M Nobile, ML Lorusso, C Baschirotto, ... Journal of Medical Genetics 41 (1), 42-46, 2004 | 66 | 2004 |
The hidden genomic landscape of acute myeloid leukemia: subclonal structure revealed by undetected mutations M Bodini, C Ronchini, L Giacò, A Russo, GEM Melloni, L Luzi, D Sardella, ... Blood, The Journal of the American Society of Hematology 125 (4), 600-605, 2015 | 65 | 2015 |
Skeletal muscle gene expression profiling in mitochondrial disorders M Crimi, A Bordoni, G Menozzi, L Riva, F Fortunate, S Galbiati, R Del Bo, ... The FASEB journal 19 (7), 1-30, 2005 | 64 | 2005 |
Polyglutamine expanded huntingtin dramatically alters the genome-wide binding of HSF1 L Riva, M Koeva, F Yildirim, L Pirhaji, D Dinesh, T Mazor, ML Duennwald, ... Journal of Huntington's disease 1 (1), 33-45, 2012 | 59 | 2012 |
Genomics of acute myeloid leukemia: the next generation L Riva, L Luzi, PG Pelicci Frontiers in oncology 2, 40, 2012 | 52 | 2012 |
RNAi screens identify CHD4 as an essential gene in breast cancer growth C D'Alesio, S Punzi, A Cicalese, L Fornasari, L Furia, L Riva, A Carugo, ... Oncotarget 7 (49), 80901, 2016 | 44 | 2016 |
DOTS-Finder: a comprehensive tool for assessing driver genes in cancer genomes GEM Melloni, AGE Ogier, S de Pretis, L Mazzarella, M Pelizzola, ... Genome medicine 6, 1-13, 2014 | 39 | 2014 |
Multi-site clonality analysis uncovers pervasive heterogeneity across melanoma metastases R Rabbie, N Ansari-Pour, O Cast, D Lau, F Scott, SJ Welsh, C Parkinson, ... Nature communications 11 (1), 1-12, 2020 | 34 | 2020 |
Peak shape clustering reveals biological insights MA Cremona, LM Sangalli, S Vantini, GI Dellino, PG Pelicci, P Secchi, ... BMC bioinformatics 16, 1-18, 2015 | 29 | 2015 |
Acute promyelocytic leukemias share cooperative mutations with other myeloid-leukemia subgroups L Riva, C Ronchini, M Bodini, F Lo-Coco, S Lavorgna, T Ottone, ... Blood Cancer Journal 3 (9), e147-e147, 2013 | 29 | 2013 |